Thomas Sakmar
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Thomas Sakmar
Thomas P. Sakmar (born 1956) is an American physician-scientist and the former acting president of The Rockefeller University. Prior to becoming acting president he was associate dean for graduate studies in the Tri-Institutional MD–PhD Program. Sakmar earned his A.B. in chemistry from University of Chicago and in 1982 received his M.D. from University of Chicago Pritzker School of Medicine. He carried out clinical training in internal medicine at Massachusetts General Hospital and postdoctoral training with H. Gobind Khorana at the Massachusetts Institute of Technology before starting the laboratory of molecular biology and biochemistry at The Rockefeller University in 1990. With 200 peer-reviewed research articles he is best known for his work on spectral tuning in photopigments and for developing drug discovery methods targeting G protein-coupled receptors. He has been a senior fellow of the Ellison Medical Foundation, an investigator of the Howard Hughes Medical Instit ...
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The Rockefeller University
The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classified among "R2: Doctoral Universities – High research activity." Rockefeller is the oldest biomedical research institute in the United States. In 2018, the faculty included 82 tenured and tenure-track members, including 37 members of the National Academy of Sciences, 17 members of the National Academy of Medicine, seven Lasker Award recipients, and five Nobel laureates. As of March 2022, a total of 26 Nobel laureates have been affiliated with Rockefeller University. The university is located on the Upper East Side of Manhattan, between 63rd and 68th streets on York Avenue. Richard P. Lifton became the university's eleventh president on September 1, 2016. The Rockefeller University Press publishes the ''Journal of Experimental Medicine'' ...
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Tri-Institutional MD–PhD Program
The Tri-Institutional MD-PhD Program is an MD-PhD program based in New York City that was formed by combining earlier MD-PhD programs that had their inceptions in 1972. The current version of the program, which is operated by Weill Cornell Medicine, The Rockefeller University, and the Memorial Sloan-Kettering Cancer Center's Sloan Kettering Institute, was created in 1991. Located in the Upper East Side of New York City, the program is currently directed by Dr. Katharine C. Hsu of the Memorial Sloan-Kettering Cancer Center. Profile Students who complete the program are awarded an M.D. from Weill Cornell Medical College and a Ph.D. from either Weill Cornell Medicine Graduate School of Medical Sciences, The Rockefeller University, or the Gerstner Sloan Kettering Graduate School of Biomedical Sciences. In 2019, the program processed over 500 applications for 18 spots. These positions are funded by the National Institutes of Health Medical Scientist Training Program (MSTP) for the fu ...
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Presidents Of Rockefeller University
President most commonly refers to: *President (corporate title) *President (education), a leader of a college or university * President (government title) President may also refer to: Automobiles * Nissan President, a 1966–2010 Japanese full-size sedan * Studebaker President, a 1926–1942 American full-size sedan * VinFast President, a 2020–present Vietnamese mid-size SUV Film and television *'' Præsidenten'', a 1919 Danish silent film directed by Carl Theodor Dreyer * ''The President'' (1928 film), a German silent drama * ''President'' (1937 film), an Indian film * ''The President'' (1961 film) * ''The Presidents'' (film), a 2005 documentary * ''The President'' (2014 film) * ''The President'' (South Korean TV series), a 2010 South Korean television series * ''The President'' (Palestinian TV series), a 2013 Palestinian reality television show *''The President Show'', a 2017 Comedy Central political satirical parody sitcom Music *The Presidents (American soul band) *The ...
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Howard Hughes Medical Investigators
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, film director, and philanthropist, known during his lifetime as one of the most financially successful individuals in the world. It is one of the largest private funding organizations for biological and medical research in the United States. HHMI spends about $1 million per HHMI Investigator per year, which amounts to annual investment in biomedical research of about $825 million. The institute has an endowment of $22.6 billion, making it the second-wealthiest philanthropic organization in the United States and the second-best endowed medical research foundation in the world. HHMI is the former owner of the Hughes Aircraft Company – an American aerospace firm which was divested to various firms over time. History The institute was fo ...
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1956 Births
Events January * January 1 – The Anglo-Egyptian Sudan, Anglo-Egyptian Condominium ends in Sudan. * January 8 – Operation Auca: Five U.S. evangelical Christian Missionary, missionaries, Nate Saint, Roger Youderian, Ed McCully, Jim Elliot and Pete Fleming, are killed for trespassing by the Huaorani people of Ecuador, shortly after making contact with them. * January 16 – Egyptian leader Gamal Abdel Nasser vows to reconquer Palestine (region), Palestine. * January 25–January 26, 26 – Finnish troops reoccupy Porkkala, after Soviet Union, Soviet troops vacate its military base. Civilians can return February 4. * January 26 – The 1956 Winter Olympics open in Cortina d'Ampezzo, Italy. February * February 11 – British Espionage, spies Guy Burgess and Donald Maclean (spy), Donald Maclean resurface in the Soviet Union, after being missing for 5 years. * February 14–February 25, 25 – The 20th Congress of the Communist Party of the Soviet Union is held in Mosc ...
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Rockefeller University
The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classified among "R2: Doctoral Universities – High research activity." Rockefeller is the oldest biomedical research institute in the United States. In 2018, the faculty included 82 tenured and tenure-track members, including 37 members of the National Academy of Sciences, 17 members of the National Academy of Medicine, seven Lasker Award recipients, and five Nobel laureates. As of March 2022, a total of 26 Nobel laureates have been affiliated with Rockefeller University. The university is located on the Upper East Side of Manhattan, between 63rd and 68th streets on York Avenue. Richard P. Lifton became the university's eleventh president on September 1, 2016. The Rockefeller University Press publishes the ''Journal of Experimental Medicine' ...
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Stockholm, Sweden
Stockholm () is the capital and largest city of Sweden as well as the largest urban area in Scandinavia. Approximately 980,000 people live in the municipality, with 1.6 million in the urban area, and 2.4 million in the metropolitan area. The city stretches across fourteen islands where Lake Mälaren flows into the Baltic Sea. Outside the city to the east, and along the coast, is the island chain of the Stockholm archipelago. The area has been settled since the Stone Age, in the 6th millennium BC, and was founded as a city in 1252 by Swedish statesman Birger Jarl. It is also the county seat of Stockholm County. For several hundred years, Stockholm was the capital of Finland as well (), which then was a part of Sweden. The population of the municipality of Stockholm is expected to reach one million people in 2024. Stockholm is the cultural, media, political, and economic centre of Sweden. The Stockholm region alone accounts for over a third of the country's GDP, ...
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University Of Copenhagen
The University of Copenhagen ( da, Københavns Universitet, KU) is a prestigious public university, public research university in Copenhagen, Copenhagen, Denmark. Founded in 1479, the University of Copenhagen is the second-oldest university in Scandinavia after Uppsala University, and ranks as one of the top universities in the Nordic countries, Europe and the world. Its establishment sanctioned by Pope Sixtus IV, the University of Copenhagen was founded by Christian I of Denmark as a Catholic teaching institution with a predominantly Theology, theological focus. In 1537, it was re-established by King Christian III as part of the Lutheran Reformation. Up until the 18th century, the university was primarily concerned with educating clergymen. Through various reforms in the 18th and 19th century, the University of Copenhagen was transformed into a modern, Secularism, secular university, with science and the humanities replacing theology as the main subjects studied and taught. Th ...
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Marie Krogh
Marie Krogh, née Jørgensen (25 December 1874 – 25 March 1943), was a Danish physician, physiologist and nutritionist. Life and work Birte Marie Krogh was born on 25 December 1874 in Vosegaard, Denmark, one of only four of nine children in her family to survive to adulthood. Due to family pressure, she was not able to attend a university-preparatory school until 1898, graduating three years later. While attending the University of Copenhagen, she met and married (1904) August Krogh, the future Nobel Laureate in physiology, in a physiology class. After Krogh graduated with her medical degree in 1907, the couple began their life-long collaboration with an expedition to Greenland to measure respiration and gas exchange in Inuit people, whose diet consisted almost exclusively of meat. Marie prematurely delivered a pair of sons in October 1908, but only one survived. Over the next two years, the couple used themselves as experimental subjects studying gas diffusion in the lungs. ...
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Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, film director, and philanthropist, known during his lifetime as one of the most financially successful individuals in the world. It is one of the largest private funding organizations for biological and medical research in the United States. HHMI spends about $1 million per HHMI Investigator per year, which amounts to annual investment in biomedical research of about $825 million. The institute has an endowment of $22.6 billion, making it the second-wealthiest philanthropic organization in the United States and the second-best endowed medical research foundation in the world. HHMI is the former owner of the Hughes Aircraft Company – an American aerospace firm which was divested to various firms over time. History The institute was fo ...
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Ellison Medical Foundation
The Ellison Medical Foundation, a 501(c)(3) Private Nonoperating Foundation, was founded in 1997 and is located in Bethesda, Maryland. The foundation supported research in the following discipline areas: biomedical research on aging, age-related diseases and disabilities. Its major philanthropic support came from Oracle CEO Larry Ellison. As of 2007, the Foundation owned 1.3 million shares of Oracle Corporation. The foundation is classified as NTEE The National Taxonomy of Exempt Entities (NTEE) is a used by the Internal Revenue Service (IRS) and NCCS to classify U.S. tax-exempt organizations. A specialist from the IRS assigns an NTEE code to each organization exempt under I.R.C. § 501(a) as ... T99—Other Philanthropy, Voluntarism, and Grantmaking Foundations N.E.C. Since 1998 the Ellison Medical Foundation has spent hundreds of millions of dollars funding fundamental research on the biology of ageing. $40 million per year was given to 25 Senior Scholars and 25 ...
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G Protein-coupled Receptor
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily-related proteins that are cell surface receptors that detect molecules outside the cell and activate cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Text was copied from this source, which is available under Attribution 2.5 Generic (CC BY 2.5) license. Ligands can bind either to extracellular N-terminus and loops (e.g. glutamate receptors) or to the binding site within transmembrane helices (Rhodopsin-like family). They are all activated by agonists although a spontaneous auto-activation of an empty receptor can also be observed. G protein-coupled receptors are found only in eukaryotes, including yeast, choanoflagellates, and ...
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