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Howard Hughes Medical Investigators
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, film director, and philanthropist, known during his lifetime as one of the most financially successful individuals in the world. It is one of the largest private funding organizations for biological and medical research in the United States. HHMI spends about $1 million per HHMI Investigator per year, which amounts to annual investment in biomedical research of about $825 million. The institute has an endowment of $22.6 billion, making it the second-wealthiest philanthropic organization in the United States and the second-best endowed medical research foundation in the world. HHMI is the former owner of the Hughes Aircraft Company – an American aerospace firm which was divested to various firms over time. History The institute was fo ...
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Howard is an English-language given name originating from Old French Huard (or Houard) from a Germanic source similar to Old High German ''*Hugihard'' "heart-brave", or ''*Hoh-ward'', literally "high defender; chief guardian". It is also probably in some cases a confusion with the Old Norse cognate ''Haward'' (''Hávarðr''), which means "high guard" and as a surname also with the unrelated Hayward. In some rare cases it is from the Old English ''eowu hierde'' "ewe herd". In Anglo-Norman the French digram ''-ou-'' was often rendered as ''-ow-'' such as ''tour'' → ''tower'', ''flour'' (western variant form of ''fleur'') → ''flower'', etc. (with svarabakhti). A diminutive is "Howie" and its shortened form is "Ward" (most common in the 19th century). Between 1900 and 1960, Howard ranked in the U.S. Top 200; between 1960 and 1990, it ranked in the U.S. Top 400; between 1990 and 2004, it ranked in the U.S. Top 600. People with the given name Howard or its variants include: Given ...
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Internal Revenue Service
The Internal Revenue Service (IRS) is the revenue service for the United States federal government, which is responsible for collecting U.S. federal taxes and administering the Internal Revenue Code, the main body of the federal statutory tax law. It is an agency of the Department of the Treasury and led by the Commissioner of Internal Revenue, who is appointed to a five-year term by the President of the United States. The duties of the IRS include providing tax assistance to taxpayers; pursuing and resolving instances of erroneous or fraudulent tax filings; and overseeing various benefits programs, including the Affordable Care Act. The IRS originates from the Commissioner of Internal Revenue, a federal office created in 1862 to assess the nation's first income tax to fund the American Civil War. The temporary measure provided over a fifth of the Union's war expenses before being allowed to expire a decade later. In 1913, the Sixteenth Amendment to the U.S. Constitutio ...
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Ashburn, Virginia
Ashburn is a census-designated place (CDP) in Loudoun County, Virginia, United States. At the 2010 United States Census, its population was 43,511, up from 3,393 twenty years earlier. It is northwest of Washington, D.C., and part of the Washington metropolitan area. Ashburn is a major hub for Internet traffic, due to its many data centers. Andrew Blum characterized it as the "bullseye of America's Internet". History Ashburn was originally called "Farmwell" (variant names include "Old Farmwell" and "Farmwell Station") after a nearby mansion of that name owned by George Lee III. The name "Farmwell" first appeared in George Lee's October 1802 will and was used to describe the plantation he inherited from his father, Thomas Ludwell Lee II. A section of Farmwell plantation west of Ashburn Road, a tract, was purchased in 1841 as a summer home by John Janney, a Quaker lawyer who nearly became Vice President of the United States. Janney called the property "Ashburn Farm"; the name's ...
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General Motors
The General Motors Company (GM) is an American Multinational corporation, multinational Automotive industry, automotive manufacturing company headquartered in Detroit, Michigan, United States. It is the largest automaker in the United States and was the largest in the world for 77 years before losing the top spot to Toyota in 2008. General Motors operates manufacturing plants in eight countries. Its four core automobile brands are Chevrolet, Buick, GMC (automobile), GMC, and Cadillac. It also holds interests in Chinese brands Wuling Motors and Baojun as well as DMAX (engines), DMAX via joint ventures. Additionally, GM also owns the BrightDrop delivery vehicle manufacturer, GM Defense, a namesake Defense vehicles division which produces military vehicles for the United States government and military; the vehicle safety, security, and information services provider OnStar; the auto parts company ACDelco, a GM Financial, namesake financial lending service; and majority ownership in t ...
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Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ...
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Immunology
Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there is a difference of human immunology and comparative immunology in veterinary medicine and animal biosciences. Immunology measures, uses charts and differentiate in context in medicine the studies of immunity on cell and molecular level, and the immune system as part of the physiological level as its functioning is of major importance. In the different states of both health, occurring symptoms and diseases; the functioning of the immune system and immunological responses such as autoimmune diseases, allergic hypersensitivities, or in some cases malfunctioning of immune system as for example in immunological disorders or in immune deficiency, and the specific transplant rejection) Immunology has applications in numerous disciplines of ...
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Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ...
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Pacific Rim
The Pacific Rim comprises the lands around the rim of the Pacific Ocean. The ''Pacific Basin'' includes the Pacific Rim and the islands in the Pacific Ocean. The Pacific Rim roughly overlaps with the geologic Pacific Ring of Fire. List of countries on the Pacific Rim This is a list of countries that are generally considered to be a part of the Pacific Rim, since they lie along the Pacific Ocean. Arranging from north to south, west to east in directional order. Oceania * Oceania (sovereign states) ** ** ** ** ** ** ** ** ** ** ** ** ** ** * Oceania ( dependent territories) ** British Overseas Territory *** ** External territory of Australia *** ** French overseas collectivities *** *** *** ** Insular Chile *** ** Realm of New Zealand *** *** *** ** United States insular areas *** *** *** ** United States *** Americas * North America ** ** ** ** ** ** ** ** ** * South America ** ** ** ** Asia * Russian Federation * Eas ...
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NATO Integrated Air Defense System
The NATO Integrated Air Defense System (short: NATINADS) is a command and control network combining radars and other facilities spread throughout the NATO alliance's air defence forces. It formed in the mid-1950s and became operational in 1962 as NADGE. It has been constantly upgraded since its formation, notably with the integration of Airborne Early Warning aircraft in the 1970s. The United Kingdom maintained its own network, but was fully integrated with the network since the introduction of the Linesman/Mediator network in the 1970s. Similarly, the German network maintained an independent nature through GEADGE. Development Development was approved by the NATO Military Committee in December 1955. The system was to be based on four air defense regions (ADRs) coordinated by SACEUR (Supreme Allied Commander Europe). Starting from 1956 early warning coverage was extended across Western Europe using 18 radar stations. This part of the system was completed by 1962. Linked to existin ...
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Bethesda, Maryland
Bethesda () is an unincorporated, census-designated place in southern Montgomery County, Maryland. It is located just northwest of Washington, D.C. It takes its name from a local church, the Bethesda Meeting House (1820, rebuilt 1849), which in turn took its name from Jerusalem's Pool of Bethesda. The National Institutes of Health's main campus and the Walter Reed National Military Medical Center are in Bethesda, in addition to a number of corporate and government headquarters. As an unincorporated community, Bethesda has no official boundaries. According to the 2020 U.S. census, the community had a total population of 68,056. History Bethesda is located in a region that was populated by the Piscataway and Nacotchtank tribes at the time of European colonization. Fur trader Henry Fleet became the first European to visit the area, reaching it by sailing up the Potomac River. He stayed with the Piscataway tribe from 1623 to 1627, either as a guest or prisoner (historical accounts ...
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Coconut Grove, Florida
Coconut Grove, also known colloquially as The Grove, is the oldest continuously inhabited neighborhood of Miami in Miami-Dade County, Florida. The neighborhood is roughly bound by North Prospect Drive to the south, LeJeune Road to the west, South Dixie Highway (US 1) and Rickenbacker Causeway to the north, and Biscayne Bay to the east. It is south of the neighborhoods of Brickell and The Roads and east of Coral Gables. The neighborhood's name has been sometimes spelled "Cocoanut Grove" but the definitive spelling "Coconut Grove" was established when the city was incorporated in 1919. What is today referred to as Coconut Grove was formed in 1925 when the city of Miami annexed two areas of about equal size, the city of Coconut Grove and most of the town of Silver Bluff. Coconut Grove approximately corresponds to the same area as the 33133 ZIP Code although the ZIP Code includes parts of Coral Way and Coral Gables and a small portion of ZIP Code 33129. The area is often referred ...
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The New York Times
''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid digital subscribers. It also is a producer of popular podcasts such as '' The Daily''. Founded in 1851 by Henry Jarvis Raymond and George Jones, it was initially published by Raymond, Jones & Company. The ''Times'' has won 132 Pulitzer Prizes, the most of any newspaper, and has long been regarded as a national " newspaper of record". For print it is ranked 18th in the world by circulation and 3rd in the U.S. The paper is owned by the New York Times Company, which is publicly traded. It has been governed by the Sulzberger family since 1896, through a dual-class share structure after its shares became publicly traded. A. G. Sulzberger, the paper's publisher and the company's chairman, is the fifth generation of the family to head the pa ...
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