Thomas Goulard
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Thomas Goulard
Thomas Goulard (1697–1784) was a French surgeon famous for Goulard's extract, a solution of lead(II) acetate and lead(II) oxide which was formerly used as an astringent. Goulard was a surgeon and anatomist in Montpellier who specialized in genitourinary The genitourinary system, or urogenital system, are the organs of the reproductive system and the urinary system. These are grouped together because of their proximity to each other, their common embryological origin and the use of common pathwa ... disorders. His best known written work is titled ''Oeuvres de Chirurgie''. References 1697 births 1784 deaths French surgeons {{France-med-bio-stub 18th-century surgeons ...
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Saint-Nicolas-de-la-Grave
Saint-Nicolas-de-la-Grave (; Languedocien: ''Sent Micolau de la Grava'') is a commune in the Tarn-et-Garonne department in the Occitanie region in southern France. Antoine Laumet de La Mothe, sieur de Cadillac, the founder of the American city of Detroit was born here in 1658. History The surroundings of Saint-Nicolas-de-la-Grave have been occupied since Roman times; the ruins of a villa were found near a place called ''Marcassus'', 2.9 km by road on the left bank of the Sère (Stream) and a capital Corinthian order in white marble was discovered at a place called 'es Arênes.'' Fragments of tile, potterys and amphora s were found to the west of the village and at a place called ''les Patots'', a very old path was an old Roman road. In the 12th century the monks of Moissac built a castle on the left bank of the Garonne, facing the confluence of the Tarn, on the edge of the plateau which dominates the alluvial plain. Because the town is a strategic crossroads, it is dispu ...
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France
France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pacific and Indian Oceans. Its Metropolitan France, metropolitan area extends from the Rhine to the Atlantic Ocean and from the Mediterranean Sea to the English Channel and the North Sea; overseas territories include French Guiana in South America, Saint Pierre and Miquelon in the North Atlantic, the French West Indies, and many islands in Oceania and the Indian Ocean. Due to its several coastal territories, France has the largest exclusive economic zone in the world. France borders Belgium, Luxembourg, Germany, Switzerland, Monaco, Italy, Andorra, and Spain in continental Europe, as well as the Kingdom of the Netherlands, Netherlands, Suriname, and Brazil in the Americas via its overseas territories in French Guiana and Saint Martin (island), ...
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Goulard's Extract
Basic lead acetate, also known as subacetate of lead, is the inorganic compound with the formula Pb3(OH)4(O2CCH3)2. A white solid, it is one of several lead acetates. History Goulard's extract is a solution of lead(II) acetate and lead(II) oxide used as an astringent during the 18th, 19th and early 20th centuries. It was named after its introducer, Thomas Goulard. Lead poisoning and the development of more effective astringents caused doctors to abandon its use. Synonymous or very closely related formulations were known as ''liquor plumbi subacetis dilutus'', ''eau de Goulard'', extract of Saturn Saturn is the sixth planet from the Sun and the second-largest in the Solar System, after Jupiter. It is a gas giant with an average radius of about nine and a half times that of Earth. It has only one-eighth the average density of Earth; h ..., vinegar of Saturn, and liquid acetate of lead. The white water ''eau de Saturne'' differed from ''eau de Goulard'' in not containing ...
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Surgeon
In modern medicine, a surgeon is a medical professional who performs surgery. Although there are different traditions in different times and places, a modern surgeon usually is also a licensed physician or received the same medical training as physicians before specializing in surgery. There are also surgeons in podiatry, dentistry, and veterinary medicine. It is estimated that surgeons perform over 300 million surgical procedures globally each year. History The first person to document a surgery was the 6th century BC Indian physician-surgeon, Sushruta. He specialized in cosmetic plastic surgery and even documented an open rhinoplasty procedure.Ira D. Papel, John Frodel, ''Facial Plastic and Reconstructive Surgery'' His magnum opus ''Suśruta-saṃhitā'' is one of the most important surviving ancient treatises on medicine and is considered a foundational text of both Ayurveda and surgery. The treatise addresses all aspects of general medicine, but the translator G. D. Si ...
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Anatomist
Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its beginnings in prehistoric times. Anatomy is inherently tied to developmental biology, embryology, comparative anatomy, evolutionary biology, and phylogeny, as these are the processes by which anatomy is generated, both over immediate and long-term timescales. Anatomy and physiology, which study the structure and function of organisms and their parts respectively, make a natural pair of related disciplines, and are often studied together. Human anatomy is one of the essential basic sciences that are applied in medicine. The discipline of anatomy is divided into macroscopic and microscopic. Macroscopic anatomy, or gross anatomy, is the examination of an animal's body parts using unaided eyesight. Gross anatomy also includes the branch of ...
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Lead(II) Acetate
Lead(II) acetate (Pb(CH3COO)2), also known as lead acetate, lead diacetate, plumbous acetate, sugar of lead, lead sugar, salt of Saturn, or Goulard's powder, is a white crystalline chemical compound with a slightly sweet taste. Like many other lead compounds, it is toxic. Lead acetate is soluble in water and glycerin. With water it forms the trihydrate, Pb(CH3COO)2·3H2O, a colourless or white efflorescent monoclinic crystalline substance. The substance is used as a reagent to make other lead compounds and as a fixative for some dyes. In low concentrations, it is the principal active ingredient in progressive types of hair colouring dyes. Lead(II) acetate is also used as a mordant in textile printing and dyeing, and as a drier in paints and varnishes. It was historically used as a sweetener and preservative in wines and in other foods and for cosmetics. Production Lead acetate can be made by boiling elemental lead in acetic acid and hydrogen peroxide. This method will also work ...
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Lead(II) Oxide
Lead(II) oxide, also called lead monoxide, is the inorganic compound with the molecular formula Pb O. PbO occurs in two polymorphs: litharge having a tetragonal crystal structure, and massicot having an orthorhombic crystal structure. Modern applications for PbO are mostly in lead-based industrial glass and industrial ceramics, including computer components. It is an amphoteric oxide. Types Lead oxide exists in two types: * Red tetragonal (α-PbO), obtained at lower temperatures than the β-PbO * Yellow orthorhombic (β-PbO), which is obtained temperatures higher than Synthesis PbO may be prepared by heating lead metal in air at approximately . At this temperature it is also the end product of decomposition of other oxides of lead in air: :PbO2->[] Pb12O19 ->[] Pb12O17 ->[] Pb3O4 ->[] PbO Thermal decomposition of lead(II) nitrate or lead carbonate, lead(II) carbonate also results in the formation of PbO: :2  → 2 PbO + 4  + : → PbO + PbO is produced ...
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Astringent
An astringent (sometimes called adstringent) is a chemical that shrinks or constricts body tissues. The word derives from the Latin ''adstringere'', which means "to bind fast". Calamine lotion, witch hazel, and yerba mansa, a Californian plant, are astringents. Astringency, the dry, puckering or numbing mouthfeel caused by the tannins in unripe fruits, lets the fruit mature by deterring eating. Ripe fruits and fruit parts including blackthorn (sloe berries), ''Aronia'' chokeberry, chokecherry, bird cherry, rhubarb, quince and persimmon fruits (especially those which are unripe), banana skins (or unripe bananas), cashew fruits and acorns are astringent. Citrus fruits, like lemons, are somewhat astringent. Tannins, being a kind of polyphenol, bind salivary proteins and make them precipitate and aggregate, producing a rough, "sandpapery", or dry sensation in the mouth. The tannins in some teas, coffee, and red grape wines like Cabernet Sauvignon and Merlot produce mild as ...
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Surgeon
In modern medicine, a surgeon is a medical professional who performs surgery. Although there are different traditions in different times and places, a modern surgeon usually is also a licensed physician or received the same medical training as physicians before specializing in surgery. There are also surgeons in podiatry, dentistry, and veterinary medicine. It is estimated that surgeons perform over 300 million surgical procedures globally each year. History The first person to document a surgery was the 6th century BC Indian physician-surgeon, Sushruta. He specialized in cosmetic plastic surgery and even documented an open rhinoplasty procedure.Ira D. Papel, John Frodel, ''Facial Plastic and Reconstructive Surgery'' His magnum opus ''Suśruta-saṃhitā'' is one of the most important surviving ancient treatises on medicine and is considered a foundational text of both Ayurveda and surgery. The treatise addresses all aspects of general medicine, but the translator G. D. Si ...
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Montpellier
Montpellier (, , ; oc, Montpelhièr ) is a city in southern France near the Mediterranean Sea. One of the largest urban centres in the region of Occitania (administrative region), Occitania, Montpellier is the prefecture of the Departments of France, department of Hérault. In 2018, 290,053 people lived in the city, while its Functional area (France), metropolitan area had a population of 787,705.Comparateur de territoire
INSEE, retrieved 20 June 2022.
The inhabitants are called Montpelliérains. In the Middle Ages, Montpellier was an important city of the Crown of Aragon (and was the birthplace of James I of Aragon, James I), and then of Kingdom of Majorca, Majorca, before its sale to France in 1349. Established in 1220, the University of Montpellier is one of the List of oldest univ ...
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Genitourinary
The genitourinary system, or urogenital system, are the organs of the reproductive system and the urinary system. These are grouped together because of their proximity to each other, their common embryological origin and the use of common pathways, like the male urethra. Also, because of their proximity, the systems are sometimes imaged together. The term "apparatus urogenitalis" was used in ''Nomina Anatomica'' (under Splanchnologia) but is not used in the current ''Terminologia Anatomica''. Development The urinary and reproductive organs are developed from the intermediate mesoderm. The permanent organs of the adult are preceded by a set of structures that are purely embryonic and that, with the exception of the ducts, disappear almost entirely before the end of fetal life. These embryonic structures are on either side: the pronephros, the mesonephros and the metanephros of the kidney, and the Wolffian and Müllerian ducts of the sex organ. The pronephros disappears very ear ...
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1697 Births
Events January–March * January 8 – Thomas Aikenhead is hanged outside Edinburgh, becoming the last person in Great Britain to be executed for blasphemy. * January 11 – French writer Charles Perrault releases the book ''Histoires ou contes du temps passé'' (literally "Tales of Past Times", known in England as "Mother Goose tales") in Paris, a collection of popular fairy tales, including ''Cinderella'', ''Puss in Boots'', ''Red Riding Hood'', ''The Sleeping Beauty'' and ''Bluebeard''. * February 8 – The English infantry regiment of Arthur Chichester, 3rd Earl of Donegall is disbanded four years after it was first raised. * February 22 – Gerrit de Heere becomes the new Governor of Dutch Ceylon, succeeding Thomas van Rhee and administering the colony for almost six years until his death. * February 26 – Conquistador Martín de Ursúa y Arizmendi and 114 soldiers arrive at Lake Petén Itzá in what is now Guatemala and begin the Spanish conquest of Guatemala with a ...
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