Thomas C. Südhof
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Thomas C. Südhof
Thomas Christian Südhof (; born December 22, 1955), ForMemRS, is a German-American biochemist known for his study of synaptic transmission. Currently, he is a professor in the School of Medicine in the Department of Molecular and Cellular Physiology, and by courtesy in Neurology, and in Psychiatry and Behavioral Sciences at Stanford University. Südhof, James Rothman and Randy Schekman are the 2013 Nobel Prize in Physiology or Medicine laureates for their work on vesicle trafficking. Early life and education A German native, Südhof was born in Göttingen in 1955. He spent his childhood in Göttingen and Hannover. He studied music in his youth, specifically the bassoon, and has credited his bassoon instructor, Herbert Tauscher, as his "most influential teacher". He was a graduate from the Hannover Waldorf School in 1975. Südhof studied medicine at the RWTH Aachen University, Harvard University, and then the University of Göttingen. In Göttingen Südhof worked on hi ...
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Baeza, Spain
Baeza () is a city and municipality of Spain belonging to the province of Jaén, in the autonomous community of Andalusia. It is part of the ''comarca'' of La Loma. It is now principally famed for having some of the best-preserved examples of Italian Renaissance architecture in Spain. Along with neighbouring Úbeda, it was added to UNESCO's list of World Heritage Sites in 2003. The former Visigothic bishopric of Baeza remains a Latin Catholic titular see. Geography The town lies perched on a cliff in the range (the ) separating the Guadalquivir River to its south from the Guadalimar to its north. History The town stands at a high elevation about from the right bank of the Guadalquivir in the Loma de Úbeda. Under the Romans, the town was known as 'Beatia'. Following its conquest by the Visigoths, Beatia was the seat of a bishopric of Baeza (viz.). From the beginning of the seventh century it was conquered by several Arab and berber states during the Al-Andalus period, ...
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Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and Tissue (biology), tissues and observe and record the effects of Product (chemistry), products in food additives and Medication, medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create Grant writing, grant proposals to obtain Funding of science, funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to ca ...
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Doctor Of Medicine
Doctor of Medicine (abbreviated M.D., from the Latin language, Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. This generally arose because many in 18th-century medical professions trained in Scotland, which used the M.D. degree nomenclature. In England, however, Bachelor of Medicine, Bachelor of Surgery was used and eventually in the 19th century became the standard in Scotland too. Thus, in the United Kingdom, Republic of Ireland, Ireland and other countries, the M.D. is a research doctorate, honorary degree, honorary doctorate or applied clinical degree restricted to those who already hold a professional degree (Bachelor's/Master's/Doctoral) in medicine. In those countries, the equivalent professional degree to the North American, and some others use of M.D., is still typically titled Bachelor of Medicine, Bachelor of Surgery (M.B ...
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Max Planck Institute For Biophysical Chemistry
The Max Planck Institute for Biophysical Chemistry (german: Max-Planck-Institut für biophysikalische Chemie), also known as the Karl-Friedrich Bonhoeffer Institute (german: Karl-Friedrich-Bonhoeffer-Institut), was a research institute of the Max Planck Society, located in Göttingen, Germany. On January 1, 2022, the institute merged with the Max Planck Institute for Experimental Medicine in Göttingen to form the Max Planck Institute for Multidisciplinary Sciences. This was the only Max Planck Institute (MPI) which combined the three classical scientific disciplines – biology, physics and chemistry. Founded in 1971, its initial focus was on problems in physics in chemistry. It had undergone a continuous evolution manifested by an expanding range of core subjects and work areas such as neurobiology, biochemistry, and molecular biology. At the time of merger, 850 people worked at the institute, about half of them scientists. Four researchers working at the institute (Stefan Hel ...
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Chromaffin Cells
Chromaffin cells, also called pheochromocytes (or phaeochromocytes), are neuroendocrine cells found mostly in the medulla of the adrenal glands in mammals. These cells serve a variety of functions such as serving as a response to stress, monitoring carbon dioxide and oxygen concentrations in the body, maintenance of respiration and the regulation of blood pressure. They are in close proximity to pre-synaptic sympathetic ganglia of the sympathetic nervous system, with which they communicate, and structurally they are similar to post-synaptic sympathetic neurons. In order to activate chromaffin cells, the splanchnic nerve of the sympathetic nervous system releases acetylcholine, which then binds to nicotinic acetylcholine receptors on the adrenal medulla. This causes the release of catecholamines. The chromaffin cells release catecholamines: ~80% of adrenaline (epinephrine) and ~20% of noradrenaline (norepinephrine) into systemic circulation for systemic effects on multiple organs ...
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Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ...
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Waldorf Education
Waldorf education, also known as Steiner education, is based on the educational philosophy of Rudolf Steiner, the founder of anthroposophy. Its educational style is Holistic education, holistic, intended to develop pupils' intellectual, artistic, and practical skills, with focus on imagination and creativity. Individual teachers have a great deal of autonomy in curriculum content, teaching methods, and governance. Formative assessments, Qualitative assessments of student work are integrated into the daily life of the classroom, with standardized testing limited to what is required to enter Higher education, post-secondary education. Many Waldorf schools have faced controversy due to Rudolf Steiner and race, Steiner's connections to racist ideology and magical thinking. Others have faced regulatory audits and closure due to concerns over substandard treatment of special needs children. The first Waldorf school opened in 1919 in Stuttgart, Germany. A century later, it has become th ...
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Bassoon
The bassoon is a woodwind instrument in the double reed family, which plays in the tenor and bass ranges. It is composed of six pieces, and is usually made of wood. It is known for its distinctive tone color, wide range, versatility, and virtuosity. It is a non-transposing instrument and typically its music is written in the bass and tenor clefs, and sometimes in the treble. There are two forms of modern bassoon: the Buffet (or French) and Heckel (or German) systems. It is typically played while sitting using a seat strap, but can be played while standing if the player has a harness to hold the instrument. Sound is produced by rolling both lips over the reed and blowing direct air pressure to cause the reed to vibrate. Its fingering system can be quite complex when compared to those of other instruments. Appearing in its modern form in the 19th century, the bassoon figures prominently in orchestral, concert band, and chamber music literature, and is occasionally heard in pop, r ...
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Hannover
Hanover (; german: Hannover ; nds, Hannober) is the capital and largest city of the German States of Germany, state of Lower Saxony. Its 535,932 (2021) inhabitants make it the List of cities in Germany by population, 13th-largest city in Germany as well as the fourth-largest city in Northern Germany after Berlin, Hamburg and Bremen. Hanover's urban area comprises the towns of Garbsen, Langenhagen and Laatzen and has a population of about 791,000 (2018). The Hanover Region has approximately 1.16 million inhabitants (2019). The city lies at the confluence of the River Leine and its tributary the Ihme, in the south of the North German Plain, and is the largest city in the Hannover–Braunschweig–Göttingen–Wolfsburg Metropolitan Region. It is the fifth-largest city in the Low German dialect area after Hamburg, Dortmund, Essen and Bremen. Before it became the capital of Lower Saxony in 1946, Hannover was the capital of the Principality of Calenberg (1636–1692), the Electorat ...
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Germans
, native_name_lang = de , region1 = , pop1 = 72,650,269 , region2 = , pop2 = 534,000 , region3 = , pop3 = 157,000 3,322,405 , region4 = , pop4 = 21,000 3,000,000 , region5 = , pop5 = 125,000 982,226 , region6 = , pop6 = 900,000 , region7 = , pop7 = 142,000 840,000 , region8 = , pop8 = 9,000 500,000 , region9 = , pop9 = 357,000 , region10 = , pop10 = 310,000 , region11 = , pop11 = 36,000 250,000 , region12 = , pop12 = 25,000 200,000 , region13 = , pop13 = 233,000 , region14 = , pop14 = 211,000 , region15 = , pop15 = 203,000 , region16 = , pop16 = 201,000 , region17 = , pop17 = 101,000 148,00 ...
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Vesicle (biology And Chemistry)
In cell biology, a vesicle is a structure within or outside a cell, consisting of liquid or cytoplasm enclosed by a lipid bilayer. Vesicles form naturally during the processes of secretion (exocytosis), uptake ( endocytosis) and transport of materials within the plasma membrane. Alternatively, they may be prepared artificially, in which case they are called liposomes (not to be confused with lysosomes). If there is only one phospholipid bilayer, the vesicles are called ''unilamellar liposomes''; otherwise they are called ''multilamellar liposomes''. The membrane enclosing the vesicle is also a lamellar phase, similar to that of the plasma membrane, and intracellular vesicles can fuse with the plasma membrane to release their contents outside the cell. Vesicles can also fuse with other organelles within the cell. A vesicle released from the cell is known as an extracellular vesicle. Vesicles perform a variety of functions. Because it is separated from the cytosol, the inside of t ...
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Randy Schekman
Randy Wayne Schekman (born December 30, 1948) is an American cell biologist at the University of California, Berkeley, former editor-in-chief of ''Proceedings of the National Academy of Sciences'' and former editor of ''Annual Review of Cell and Developmental Biology''. In 2011, he was announced as the editor of ''eLife'', a new high-profile open-access journal published by the Howard Hughes Medical Institute, the Max Planck Society and the Wellcome Trust launching in 2012. He was elected to the National Academy of Sciences in 1992. Schekman shared the 2013 Nobel Prize for Physiology or Medicine with James Rothman and Thomas C. Südhof for their ground-breaking work on cell membrane vesicle trafficking. Early life and education Schekman was born in Saint Paul, Minnesota, to Alfred Schekman, an electrical engineer and computer software designer and Esther (Bader) Schekman. His family were Jewish emigrants from Russia and Bessarabia. In the late 1950s his family moved to the new s ...
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