Talaromyces Verruculosus
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Talaromyces Verruculosus
''Penicillium velutinum'' is an anamorph species of fungus in the genus '' Penicillium'' which was isolated from soil in the United States. It produces verruculogen, verrucosidin Verrucosidin is a toxic pyrone-type polyketide produced by ''Penicillium aurantiogriseum ''Penicillium aurantiogriseum'' is a plant pathogen infecting asparagus and strawberry. Chemical compounds isolated from ''Penicillium aurantiogriseum'' i ..., verruculotoxin, decalpenic acid, dehydroaltenusin, cyciooctasulfur, atrovenetinone, altenusin and penitrem A Further reading * * * * * * * * * * * * * References {{Taxonbar, from=Q10623087 verruculosum Fungi described in 1913 ...
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Anamorph
In mycology, the terms teleomorph, anamorph, and holomorph apply to portions of the life cycles of fungi in the phyla Ascomycota and Basidiomycota: *Teleomorph: the sexual reproductive stage (morph), typically a fruiting body. *Anamorph: an asexual reproductive stage (morph), often mold-like. When a single fungus produces multiple morphologically distinct anamorphs, these are called synanamorphs. *Holomorph: the whole fungus, including anamorphs and teleomorph. Dual naming of fungi Fungi are classified primarily based on the structures associated with sexual reproduction, which tend to be evolutionarily conserved. However, many fungi reproduce only asexually, and cannot easily be classified based on sexual characteristics; some produce both asexual and sexual states. These problematic species are often members of the Ascomycota, but a few of them belong to the Basidiomycota. Even among fungi that reproduce both sexually and asexually, often only one method of reproduction can be ...
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Penicillium
''Penicillium'' () is a genus of ascomycetous fungi that is part of the mycobiome of many species and is of major importance in the natural environment, in food spoilage, and in food and drug production. Some members of the genus produce penicillin, a molecule that is used as an antibiotic, which kills or stops the growth of certain kinds of bacteria. Other species are used in cheesemaking. According to the ''Dictionary of the Fungi'' (10th edition, 2008), the widespread genus contains over 300 species. Taxonomy The genus was first described in the scientific literature by Johann Heinrich Friedrich Link in his 1809 work ''Observationes in ordines plantarum naturales''; he wrote, "''Penicillium. Thallus e floccis caespitosis septatis simplicibus aut ramosis fertilibus erectis apice penicillatis''", where ''penicillatis'' means "having tufts of fine hair". Link included three species—'' P. candidum'', '' P. expansum'', and '' P. glaucum''—all of which produ ...
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Deutsche Sammlung Von Mikroorganismen Und Zellkulturen
The Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH (German: ''Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH''), located in Braunschweig, is a research infrastructure in the Leibniz Association. Also the DSMZ is the world's most diverse collection of bioresources (status 2021: 75,000 bioresources). These include microorganisms (including more than 32,000 bacterial strains, 690 archaeal strains, 7,000 strains of yeasts and fungi) as well as more than 840 human and animal cell cultures, over 1. 500 plant viruses, over 940 bacteriophages, and 250 plasmids (status 2021). Since 2010, the scientific director of the Leibniz Institute DSMZ has been Jörg Overmann, a microbiologist with a PhD. He holds a professorship in microbiology at the Technical University of Braunschweig. Since August 2018, he has led the institute in a dual leadership with Bettina Fischer as administrative director. History Structure ...
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Verruculogen
Verruculogen is a mycotoxin produced by certain strains of ''aspergillus'' that belongs to a class of naturally occurring 2,5-diketopiperazines. It is an annulated analogue of cyclo(L-Trp-L-Pro) which belongs to the most abundant and structurally diverse class of tryptophan-proline 2,5-diketopiperazine natural products. It produces tremors in mice due to its neurotoxic properties. It also tested positive in a ''Salmonella''/mammalian microsome assay and was shown to be genotoxic. It is a potent blocker of calcium-activated potassium channel Calcium-activated potassium channels are potassium channels gated by calcium, or that are structurally or phylogenetically related to calcium gated channels. They were first discovered in 1958 by Gardos who saw that calcium levels inside of a cell ...s.http://www.sigmaaldrich.com/catalog/product/sigma/v7755?lang=en®ion=US Synthesis Both verruculogen and its isoprenyl derivative fumitremorgin A belong to the only family of alkaloids wit ...
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Verrucosidin
Verrucosidin is a toxic pyrone-type polyketide produced by ''Penicillium aurantiogriseum ''Penicillium aurantiogriseum'' is a plant pathogen infecting asparagus and strawberry. Chemical compounds isolated from ''Penicillium aurantiogriseum'' include anicequol Anicequol (developmental code names NGA0187, NGD-187) is a naturally oc ...'', Penicillium melanoconidium, and Penicillium polonicum. References {{organic-compound-stub 2-Pyrones Epoxides Verrucosidin Polyketides Lactones Methoxy compounds ...
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Dehydroaltenusin
Dehydroaltenusin is an inhibitor of mammalian DNA polymerase α. It has been isolated from the fungus ''Alternaria tenuis ''Alternaria alternata'' is a fungus which has been recorded causing leaf spot and other diseases on over 380 host species of plant. It is an opportunistic pathogen on numerous hosts causing leaf spots, rots and blights on many plant parts. It ...''. References Polyphenols Lactones {{organic-compound-stub ...
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Penitrem A
Penitrem A (tremortin) is an indole-diterpenoid mycotoxin produced by certain species of ''Aspergillus'', ''Claviceps'', and ''Penicillium'', which can be found growing on various plant species such as ryegrass. Penitrem A is one of many secondary metabolites following the synthesis of paxilline in '' Penicillium crostosum''. Penitrem A poisoning in humans and animals usually occurs through the consumption of contaminated foods by mycotoxin-producing species, which is then distributed through the body by the bloodstream. It bypasses the blood-brain barrier to exert its toxicological effects on the central nervous system. In humans, penitrem A poisoning has been associated with severe tremors, hyperthermia, nausea/vomiting, diplopia, and bloody diarrhea. In animals, symptoms of penitrem A poisoning has been associated with symptoms ranging from tremors, seizures, and hyperthermia to ataxia and nystagmus. Roquefortine C has been commonly detected in documented cases of penitrem A p ...
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