Dehydroaltenusin is an inhibitor of mammalian
DNA polymerase
A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA. These enzymes are essential for DNA replication and usually work in groups to create ...
α.
It has been isolated from the fungus ''
Alternaria tenuis
''Alternaria alternata'' is a fungus which has been recorded causing leaf spot and other diseases on over 380 host species of plant. It is an opportunistic pathogen on numerous hosts causing leaf spots, rots and blights on many plant parts.
It ...
''.
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References
Polyphenols
Lactones
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