Tylvalosin
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Tylvalosin
Tylvalosin, sold under the brand name Aivlosin, is a macrolide antibiotic used for the treatment of bacterial infections with ''Mycoplasma hyopneumoniae'' in swine, that causes enzootic pneumonia. It is used as tylvalosin tartrate. Mechanism of Action Macrolides are generally considered to be bacteriostatic agents that exert their antibiotic effect by reversibly binding to the 23S rRNA of the 50S ribosomal subunit, thereby inhibiting bacterial protein synthesis. Medical uses Tylvalosin is indicated for the control of porcine proliferative enteropathy associated with ''Lawsonia intracellularis'' infection in groups of swine intended for slaughter and female swine intended for breeding in buildings experiencing an outbreak of PPE. Not for use in male swine intended for breeding; and for the control of swine respiratory disease associated with ''Bordetella bronchiseptica'', ''Glaesserella (Haemophilus) parasuis'', ''Pasteurella multocida'', ''Streptococcus suis'', and ''Mycop ...
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By Mouth
Oral administration is a route of administration where a substance is taken through the mouth. Per os abbreviated to P.O. is sometimes used as a direction for medication to be taken orally. Many medications are taken orally because they are intended to have a systemic effect, reaching different parts of the body via the bloodstream, for example. Oral administration can be easier and less painful than other routes, such as injection. However, the onset of action is relatively low, and the effectiveness is reduced if it is not absorbed properly in the digestive system, or if it is broken down by digestive enzymes before it can reach the bloodstream. Some medications may cause gastrointestinal side effects, such as nausea or vomiting, when taken orally. Oral administration can also only be applied to conscious patients, and patients willing and able to swallow. Terminology ''Per os'' (; ''P.O.'') is an adverbial phrase meaning literally from Latin "through the mouth" or "by mou ...
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