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Trypanosoma Congolense
''Trypanosoma congolense'' is a species of trypanosomes and is the major pathogen responsible for the disease nagana in cattle and other animals including sheep, pigs, goats, horses and camels, dogs, as well as laboratory mice. It is the most common cause of nagana in east Africa, but is also a major cause of nagana in west Africa. This parasite is spread by tsetse flies. In its mammalian host, ''Trypanosoma congolense'' only lives in blood vessels, and causes in particular anaemia. African Animal Trypanosomiasis
, USAHA gray book, 6th ed. (1998).


Infection process

''T. congolense'' causes . Nok et al 2003 find ''T. congolense'' to alter the surfaces of ...
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American Association Of Veterinary Parasitologists
The American Association of Veterinary Parasitologists is a professional association for veterinary parasitology. Despite the name it primarily serves both the United States and Canada and to a lesser degree the entire world. The AAVP connects veterinary parasitologists to each other and provides recommendations as to research and practice methods. Journals As part of its professional development and education mission the AAVP publishes: * Veterinary Parasitology along with Elsevier Elsevier () is a Dutch academic publishing company specializing in scientific, technical, and medical content. Its products include journals such as ''The Lancet'', ''Cell'', the ScienceDirect collection of electronic journals, '' Trends'', th ... References External links * Health care-related professional associations based in the United States Veterinary medicine-related professional associations Veterinary medicine in the United States {{Zoology-stub ...
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Veterinary Parasitology (journal)
''Veterinary Parasitology'' is a peer-reviewed scientific journal In academic publishing, a scientific journal is a periodical publication intended to further the progress of science, usually by reporting new research. Content Articles in scientific journals are mostly written by active scientists such as s ... in the discipline of veterinary parasitology. It is the official organ of the American Association of Veterinary Parasitologists, the European Veterinary Parasitology College, and the World Association for the Advancement of Veterinary Parasitology. References External links * Veterinary medicine journals Parasitology journals Elsevier academic journals Publications established in 1975 {{zoo-journal-stub ...
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Parasites Of Equines
Parasitism is a close relationship between species, where one organism, the parasite, lives on or inside another organism, the host, causing it some harm, and is adapted structurally to this way of life. The entomologist E. O. Wilson has characterised parasites as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the broomrapes. There are six major parasitic strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), trophicallytransmitted parasitism (by being eaten), vector-transmitted parasitism, parasitoidism, and micropredation. One major axis of classification concerns invasiveness: an endoparasite lives inside the host's body; an ect ...
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Trypanosomatida
Trypanosomatida is a group of kinetoplastid excavates distinguished by having only a single flagellum. The name is derived from the Greek ''trypano'' (borer) and ''soma'' (body) because of the corkscrew-like motion of some trypanosomatid species. All members are exclusively parasitic, found primarily in insects. A few genera have life-cycles involving a secondary host, which may be a vertebrate, invertebrate or plant. These include several species that cause major diseases in humans. Some trypanosomatida are intracellular parasites, with the important exception of Trypanosoma brucei. Medical importance The three major human diseases caused by trypanosomatids are; African trypanosomiasis (sleeping sickness, caused by ''Trypanosoma brucei'' and transmitted by tsetse flies), South American trypanosomiasis (Chagas disease, caused by '' T. cruzi'' and transmitted by triatomine bugs), and leishmaniasis (a set of trypanosomal diseases caused by various species of ''Leishmania'' trans ...
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Acta Tropica
Elsevier () is a Dutch academic publishing company specializing in scientific, technical, and medical content. Its products include journals such as ''The Lancet'', ''Cell'', the ScienceDirect collection of electronic journals, '' Trends'', the '' Current Opinion'' series, the online citation database Scopus, the SciVal tool for measuring research performance, the ClinicalKey search engine for clinicians, and the ClinicalPath evidence-based cancer care service. Elsevier's products and services also include digital tools for data management, instruction, research analytics and assessment. Elsevier is part of the RELX Group (known until 2015 as Reed Elsevier), a publicly traded company. According to RELX reports, in 2021 Elsevier published more than 600,000 articles annually in over 2,700 journals; as of 2018 its archives contained over 17 million documents and 40,000 e-books, with over one billion annual downloads. Researchers have criticized Elsevier for its high profit margin ...
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Homidium Chloride
Ethidium bromide (or homidium bromide, chloride salt homidium chloride) is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis. It is commonly abbreviated as EtBr, which is also an abbreviation for bromoethane. To avoid confusion, some laboratories have used the abbreviation EthBr for this salt. When exposed to ultraviolet light, it will fluoresce with an orange colour, intensifying almost 20-fold after binding to DNA. Under the name homidium, it has been commonly used since the 1950s in veterinary medicine to treat trypanosomiasis in cattle. The high incidence of antimicrobial resistance makes this treatment impractical in some areas, where the related isometamidium chloride is used instead. Despite its reputation as a mutagen, it is relatively safe to handle. Structure, chemistry, and fluorescence As with most fluorescent compounds, ethidium bromide is aromatic. ...
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Isometamidium Chloride
Isometamidium chloride is a triazene trypanocidal agent used in veterinary medicine. It consists of a single Ethidium bromide like subunit linked to a fragment of the diminazene molecule. Resistance The Gibe River Valley in southwest Ethiopia showed universal resistance between July 1989 and February 1993. This likely indicates a permanent loss of function in this area against the tested target, '' T. congolense'' isolated from Boran Boran (also spelled Buran, Middle Persian: ; New Persian: پوران‌دخت, ''Pūrāndokht'') was Sasanian queen (or '' banbishn'') of Iran from 630 to 632, with an interruption of some months. She was the daughter of king (or ''shah'') Kho ... cattle. References Amidines Antiparasitic agents Quaternary ammonium compounds {{antiinfective-drug-stub ...
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Diminazene Aceturate
Diminazene (INN; also known as diminazen) is an anti-infective medication for animals that is sold under a variety of brand names. It is effective against certain protozoa such as ''Babesia'', ''Trypanosoma'', and '' Cytauxzoon''. The drug may also be effective against certain bacteria including ''Brucella'' and ''Streptococcus''. Chemically it is a di-amidine and it is formulated as its aceturate salt, diminazene aceturate. The mechanism is not well understood; it probably inhibits DNA replication, but also has affinity to RNA. __TOC__ Side effects Acute side effects include vomiting, diarrhea, and hypotension (low blood pressure). Diminazen can harm the liver, kidneys and brain, which is potentially life-threatening; camels are especially susceptible to these effects. Resistance The Gibe River Valley in southwest Ethiopia showed universal resistance between July 1989 and February 1993. This likely indicates a permanent loss of function in this area against the tested target, ...
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Ethiopia
Ethiopia, , om, Itiyoophiyaa, so, Itoobiya, ti, ኢትዮጵያ, Ítiyop'iya, aa, Itiyoppiya officially the Federal Democratic Republic of Ethiopia, is a landlocked country in the Horn of Africa. It shares borders with Eritrea to the north, Djibouti to the northeast, Somalia to the east and northeast, Kenya to the south, South Sudan to the west, and Sudan to the northwest. Ethiopia has a total area of . As of 2022, it is home to around 113.5 million inhabitants, making it the 13th-most populous country in the world and the 2nd-most populous in Africa after Nigeria. The national capital and largest city, Addis Ababa, lies several kilometres west of the East African Rift that splits the country into the African and Somali tectonic plates. Anatomically modern humans emerged from modern-day Ethiopia and set out to the Near East and elsewhere in the Middle Paleolithic period. Southwestern Ethiopia has been proposed as a possible homeland of the Afroasiatic langua ...
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Gibe River
The Gibe River (also Great Gibe River) is by far the largest tributary of the Omo River in Ethiopia and typically flowing south-southeast. The confluence of the large Gibe River at with the smaller Wabe River forms the even larger Omo River. Consequently, the whole drainage basin is sometimes called the ''Omo-Gibe River Basin'' with the Gibe and the Omo draining the upper and lower reaches, respectively. Located in southwest Ethiopia, the Gibe River is not navigable, like almost all rivers in the country. Overview The Gibe rises at an elevation of more than 2,000 m north of Bila town and west of the Chomen swamp (specifically, from Gudeya Bila woreda, which is located in the East Welega Zone, Oromia Region). The river is then flowing generally to the southeast to its confluence with the Wabe River. Its tributaries include the Amara, Alanga and Gilgel Gibe rivers. The southern drainage area of the Gibe includes the historic Gibe region, where a number of the former kingdoms o ...
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Boran
Boran (also spelled Buran, Middle Persian: ; New Persian: پوران‌دخت, ''Pūrāndokht'') was Sasanian queen (or '' banbishn'') of Iran from 630 to 632, with an interruption of some months. She was the daughter of king (or ''shah'') Khosrow II () and the Byzantine princess Maria. She is the second of only three women to rule in Iranian history, the others being Musa of Parthia, and Boran's sister Azarmidokht. In 628, her father was overthrown and executed by her brother-husband Kavad II, who also had all Boran's brothers and half-brothers executed, initiating a period of fractionalism within the empire. Kavad II died some months later, and was succeeded by his eight-year-old son Ardashir III, who after a rule of nigh two years, was killed and usurped by the Iranian military officer Shahrbaraz. Boran shortly ascended the throne with the aid of the military commander Farrukh Hormizd, who helped her to overthrow Shahrbaraz. She and her sister were the only legitimate heirs ...
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Elsevier
Elsevier () is a Dutch academic publishing company specializing in scientific, technical, and medical content. Its products include journals such as ''The Lancet'', ''Cell'', the ScienceDirect collection of electronic journals, '' Trends'', the '' Current Opinion'' series, the online citation database Scopus, the SciVal tool for measuring research performance, the ClinicalKey search engine for clinicians, and the ClinicalPath evidence-based cancer care service. Elsevier's products and services also include digital tools for data management, instruction, research analytics and assessment. Elsevier is part of the RELX Group (known until 2015 as Reed Elsevier), a publicly traded company. According to RELX reports, in 2021 Elsevier published more than 600,000 articles annually in over 2,700 journals; as of 2018 its archives contained over 17 million documents and 40,000 e-books, with over one billion annual downloads. Researchers have criticized Elsevier for its high profit marg ...
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