|
Trolnitrate
Trolnitrate is an organic nitrate with vasodilator activity that is used to prevent or ameliorate attacks of angina pectoris. Trolnitrate dilates the coronary vessels because of its basic action as a smooth muscle depressant, just as do nitroglycerin and other organic nitrates. References Nitrate esters {{cardiovascular-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nitrate (pharmacology)
A nitrovasodilator is a pharmaceutical agent that causes vasodilation (widening of blood vessels) by donation of nitric oxide (NO), and is mostly used for the treatment and prevention of angina pectoris. This group of drugs includes nitrates (esters of nitric acid), which are reduced to NO in the body, as well as some other substances. Examples Here is a list of examples of the nitrate type (in alphabetical order): #Diethylene glycol dinitrate #Glyceryl trinitrate (nitroglycerin) #Isosorbide mononitrate and dinitrate # Itramin tosilate # Nicorandil (which additionally acts as a potassium channel opener) # Pentaerithrityl tetranitrate # Propatylnitrate # Sinitrodil #Tenitramine # Trolnitrate Nitrovasodilators which aren't nitrates include molsidomine and its active metabolite linsidomine, as well as sodium nitroprusside. These substances do not need to be reduced to donate NO. Medical uses The nitrates are used for the treatment and prevention of angina and acute my ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nitroglycerin (drug)
Nitroglycerin, also known as glyceryl trinitrate (GTN), is a medication used for heart failure, high blood pressure, anal fissures, painful periods, and to treat and prevent chest pain caused by decreased blood flow to the heart (angina) or due to the recreational use of cocaine. This includes chest pain from a heart attack. It is taken by mouth, under the tongue, applied to the skin, or by injection into a vein. Common side effects include headache and low blood pressure. The low blood pressure can be severe. It is unclear if use in pregnancy is safe for the baby. It should not be used together with medications within the PDE5 inhibitor family such as sildenafil due to the risk of low blood pressure. Nitroglycerin is in the nitrate family of medications. While it is not entirely clear how it works, it is believed to function by dilating blood vessels. Nitroglycerin was written about as early as 1846 and came into medical use in 1878. It is on the World Health Organizat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
