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Treat Baldwin Johnson
Treat Baldwin Johnson (29 March 1875 – 28 July 1947) was an American organic chemist and Sterling Professor at Yale University from 1928–1943. Early life and education Treat Baldwin Johnson was born in Bethany, Connecticut, on 29 March 1875, the oldest of three sons of Dwight Lauren Johnson and Harriet Adeline Baldwin. He was educated at Ansonia High School (Connecticut), Ansonia high school and graduated from the Sheffield Scientific School of Yale University in 1898, where he obtained work as a laboratory assistant and began a Doctor of Philosophy, Ph.D. degree under the supervision of H L Wheeler. By the time of its completion in 1901, Johnson had published seven scientific papers relating mainly to imidoesters. Career Johnson became an instructor of chemistry at the Sheffield Scientific School in 1902 and then an assistant professor in 1909. He specialized in organic chemistry and was promoted to full professor in 1914. In 1918, he received the William H. Nichols Medal, N ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bethany, Connecticut
Bethany is a town in New Haven County, Connecticut, United States. The population was 5,297 at the 2020 census. History Bethany was first settled in 1717, but it was not until May 1832 that Bethany separated from Woodbridge to become incorporated as a town. This slightly remote, sparsely populated, residential town retains its rural character. There is some dairying and agriculture. The town is dotted with reservoirs serving Naugatuck and, principally, New Haven. There have been inhabitants in Bethany since before 1638, predominantly Naugatucks of the Paugusset tribe and Mattabessitts of the Wanguck tribe. The first European settlers arrived in the area around April 1638, creating the towns of Milford and New Haven, with their boundary split down the middle of what is now Bethany. The area of the boundary was settled in 1678, twelve years after New Haven County was organized. In 1717, the Amity Parish was accepted by the General Assembly of the Connecticut Colony and in 1832, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pyrimidine
Pyrimidine (; ) is an aromatic, heterocyclic, organic compound similar to pyridine (). One of the three diazines (six-membered heterocyclics with two nitrogen atoms in the ring), it has nitrogen atoms at positions 1 and 3 in the ring. The other diazines are pyrazine (nitrogen atoms at the 1 and 4 positions) and pyridazine (nitrogen atoms at the 1 and 2 positions). In nucleic acids, three types of nucleobases are pyrimidine derivatives: cytosine (C), thymine (T), and uracil (U). Occurrence and history The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives, including the nucleotides cytosine, thymine and uracil, thiamine (vitamin B1) and alloxan. It is also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Although pyrimidine derivatives such as alloxan were known in the early 19th century, a laboratory synthesis of a pyrimidine was not carried out until 1879, when Grimaux reporte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1947 Deaths
It was the first year of the Cold War, which would last until 1991, ending with the dissolution of the Soviet Union. Events January * January– February – Winter of 1946–47 in the United Kingdom: The worst snowfall in the country in the 20th century causes extensive disruption of travel. Given the low ratio of private vehicle ownership at the time, it is mainly remembered in terms of its effects on the railway network. * January 1 - The Canadian Citizenship Act comes into effect. * January 4 – First issue of weekly magazine ''Der Spiegel'' published in Hanover, Germany, edited by Rudolf Augstein. * January 10 – The United Nations adopts a resolution to take control of the free city of Trieste. * January 15 – Elizabeth Short, an aspiring actress nicknamed the " Black Dahlia", is found brutally murdered in a vacant lot in Los Angeles; the mysterious case is never solved. * January 16 – Vincent Auriol is inaugurated as president of France. * January 19 †... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1875 Births
Events January–March * January 1 – The Midland Railway of England abolishes the Second Class passenger category, leaving First Class and Third Class. Other British railway companies follow Midland's lead during the rest of the year (Third Class is renamed Second Class in 1956). * January 5 – The Palais Garnier, one of the most famous opera houses in the world, is inaugurated in Paris. * January 12 – Guangxu becomes the 11th Qing Dynasty Emperor of China at the age of 3, in succession to his cousin. * January 14 – The newly proclaimed King Alfonso XII of Spain (Queen Isabella II's son) arrives in Spain to restore the monarchy during the Third Carlist War. * February 3 – Third Carlist War – Battle of Lácar: Carlist commander Torcuato MendÃri secures a brilliant victory, when he surprises and routs a Government force under General Enrique Bargés at Lácar, east of Estella, nearly capturing newly crowned King Alfonso XII. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mycobacterium Tuberculosis
''Mycobacterium tuberculosis'' (M. tb) is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, ''M. tuberculosis'' has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining, and as a result, ''M. tuberculosis'' can appear weakly Gram-positive. Acid-fast stains such as Ziehl–Neelsen, or fluorescent stains such as auramine are used instead to identify ''M. tuberculosis'' with a microscope. The physiology of ''M. tuberculosis'' is highly aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the tuberculin skin test, acid-fast stain, culture, and polymerase chain reaction. The ''M. tuberculosis'' genome was sequenced in 1998. Microbiology In 2019, M. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nucleotide
Nucleotides are organic molecules consisting of a nucleoside and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth. Nucleotides are obtained in the diet and are also synthesized from common nutrients by the liver. Nucleotides are composed of three subunit molecules: a nucleobase, a five-carbon sugar ( ribose or deoxyribose), and a phosphate group consisting of one to three phosphates. The four nucleobases in DNA are guanine, adenine, cytosine and thymine; in RNA, uracil is used in place of thymine. Nucleotides also play a central role in metabolism at a fundamental, cellular level. They provide chemical energy—in the form of the nucleoside triphosphates, adenosine triphosphate (ATP), guanosine triphosphate (GTP), cytidine triphosphate (CTP) and uridine triphosphate (UTP)—throughout the cell for the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tuberculinic Acid
Tuberculinic acid is a noncanonical nucleic acid initially identified as the poison of ''Tubercle bacillus'' (='' Mycobacterium tuberculosis''), the principal causative bacterium of tuberculosis. Its discovery was one of the most important landmarks in understanding tuberculosis and in molecular biology. It is regarded as the most toxic component of the bacillus. It was from this compound that DNA methylation was discovered as it was the first molecule found to contain 5-methylcytosine. In addition it contains thymine, guanine and cytosine. Discovery It was first identified by a German chemist W.G. Ruppel in 1898 while trying to isolate the bacterial toxin responsible for tuberculosis. From the crushed bacilli, specifically the protein tuberculin, he isolated two toxic substances, namely a basic compound which he called tuberculosamine, and a nucleotide he named tuberculisäure, later to be anglicised to tuberculinic acid. He claimed that the tuberculosamin was bound to the n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemistry Set
A chemistry set is an educational toy allowing the user (typically a teenager) to perform simple chemistry experiments. History Forerunners The forerunners of the chemistry set were 17th century books on "natural magick", "which all excellent wise men do admit and embrace, and worship with great applause; neither is there any thing more highly esteemed, or better thought of, by men of learning." Authors such as Giambattista della Porta included chemical magic tricks and scientific puzzles along with more serious topics. The earliest chemistry sets were developed in the 18th century in England and Germany to teach chemistry to adults. In 1791, ''Description of a portable chest of chemistry : or, Complete collection of chemical tests for the use of chemists, physicians, mineralogists, metallurgists, scientific artists, manufacturers, farmers, and the cultivators of natural philosophy'' by Johann Friedrich August Göttling, translated from German, was published in English. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Owner's Manual
An owner's manual (also called an instruction manual or a user guide) is an instructional book or booklet that is supplied with almost all technologically advanced consumer products such as vehicles, home appliances and computer peripherals. Information contained in the owner's manual typically includes: * Safety instructions; for liability reasons these can be extensive, often including warnings against performing operations that are ill-advised for product longevity or overall user safety reasons. * Assembly instructions; for products that arrive in pieces for easier shipping. * Installation instructions; for products that need to be installed in a home or workplace. * Setup instructions; for devices that keep track of time or which maintain user accessible state. * Instructions for normal or intended operations. * Programming instructions; for microprocessor controlled products such as VCRs, programmable calculators, and synthesizers. * Maintenance instructions. * Troubl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Silk
Silk is a natural protein fiber, some forms of which can be woven into textiles. The protein fiber of silk is composed mainly of fibroin and is produced by certain insect larvae to form cocoons. The best-known silk is obtained from the cocoons of the larvae of the mulberry silkworm ''Bombyx mori'' reared in captivity ( sericulture). The shimmering appearance of silk is due to the triangular prism-like structure of the silk fibre, which allows silk cloth to refract incoming light at different angles, thus producing different colors. Silk is produced by several insects; but, generally, only the silk of moth caterpillars has been used for textile manufacturing. There has been some research into other types of silk, which differ at the molecular level. Silk is mainly produced by the larvae of insects undergoing complete metamorphosis, but some insects, such as webspinners and raspy crickets, produce silk throughout their lives. Silk production also occurs in hymenoptera ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacology
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous Biological activity, bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered Pharmaceutical drug, pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanism of action, mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, drug interaction, interactions, chemical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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