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Transcorneal Electrical Stimulation
Transcorneal electrical stimulation (TES) is a therapy developed for use in patients with a variety of eye diseases. The procedure involves placing electrodes in the form of contact lenses upon the patient's corneas, with a reference electrode on the skin near each eye. A weak current is delivered through the electrodes, with the intent of stimulating the visual system and enhancing its activity. As of 2022, the technique was still in the early stages of research in human patients. A review of literature published in 2020 estimated this therapy as "probably effective" in the treatment of retinitis pigmentosa Retinitis pigmentosa (RP) is a genetic disorder of the eyes that causes loss of vision. Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visual field). As peripheral vision worsens, people may ..., based on the evidence available at the time. References Ophthalmology {{Ophthalmology-stub ...
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Retinitis Pigmentosa
Retinitis pigmentosa (RP) is a genetic disorder of the eyes that causes loss of vision. Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visual field). As peripheral vision worsens, people may experience "tunnel vision". Complete blindness is uncommon. Onset of symptoms is generally gradual and often begins in childhood. Retinitis pigmentosa is generally inherited from one or both parents or rarely it can be caused by a miscoding during DNA division. It is caused by genetic miscoding of proteins in one of more than 300 genes involved. The underlying mechanism involves the progressive loss of rod photoreceptor cells that line the retina of the eyeball. The rod cells secrete a neuroprotective substance (Rod-derived cone viability factor, RdCVF) that protects the cone cells from apoptosis (cell death). However, when the rod cells die, this substance is no longer provided. This is generally followed by the loss of cone photorecept ...
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