Tranquillizer
A tranquilizer is a drug that is designed for the treatment of anxiety, fear, tension, agitation, and disturbances of the mind, specifically to reduce states of anxiety and tension. Etymology Tranquilizer, as a term, was first used by F.F. Yonkman (1953), from the conclusions of investigative studies using the drug reserpine, which showed the drug had a calming effect on all animals to which it was administered. Reserpine is a centrally acting Rauwolfia alkaloid. The word directly refers to the state of tranquillity in a person and other animals. The term is considered ''popular'' or ''common'', meaning it is not generally in use in the field of medicine. Specifically, it is used in reference to antipsychotic or neuroleptic medications. The term is generally used as a synonym for sedative. When used by health care professionals, it is usually qualified or replaced with more precise terms: * minor tranquilizer usually refers to anxiolytics. * major tranquilizer might refer to a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tranquilliser Gun
A dart gun is an air rifle that fires a dart. The dart is tipped with a hypodermic needle and filled with a tranquilizer, vaccine, or antibiotic. A dart gun containing a tranquillizer is called a tranquillizer gun ( also spelled tranquilizer, tranquilliser or tranquiliser). History The modern dart gun was invented in the 1950s by New Zealander Colin Murdoch. While working with colleagues to study populations of deer and wild goats introduced to New Zealand, he considered that the animals would be easier to catch, examine, and release if a dose of tranquillizer could be administered by projection from afar. To that end, Murdoch went on to develop a range of rifles, darts, and pistols. The first modern remote drug-delivery system was invented by scientists at the University of Georgia in the 1950s, and was the direct predecessor to the Cap-Chur equipment used worldwide for decades. In the early 1960s, a team in Kenya headed by Drs. Tony Pooley and Toni Harthoorn discovered that ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Dart Gun
A dart gun is an air rifle that fires a dart. The dart is tipped with a hypodermic needle and filled with a tranquilizer, vaccine, or antibiotic. A dart gun containing a tranquillizer is called a tranquillizer gun ( also spelled tranquilizer, tranquilliser or tranquiliser). History The modern dart gun was invented in the 1950s by New Zealander Colin Murdoch. While working with colleagues to study populations of deer and wild goats introduced to New Zealand, he considered that the animals would be easier to catch, examine, and release if a dose of tranquillizer could be administered by projection from afar. To that end, Murdoch went on to develop a range of rifles, darts, and pistols. The first modern remote drug-delivery system was invented by scientists at the University of Georgia in the 1950s, and was the direct predecessor to the Cap-Chur equipment used worldwide for decades. In the early 1960s, a team in Kenya headed by Drs. Tony Pooley and Toni Harthoorn discovered that ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sedative
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are CNS depressants and interact with brain activity causing its deceleration. Various kinds of sedatives can be distinguished, but the majority of them affect the neurotransmitter gamma-aminobutyric acid (GABA). In spite of the fact that each sedative acts in its own way, most produce relaxing effects by increasing GABA activity. This group is related to hypnotics. The term ''sedative'' describes drugs that serve to calm or relieve anxiety, whereas the term ''hypnotic'' describes drugs whose main purpose is to initiate, sustain, or lengthen sleep. Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness) they are often referred to collectively as ''sedative-hypnotic'' drugs. Sedatives can be used to produce an overly-calming effect ( alcohol being the m ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sedative
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are CNS depressants and interact with brain activity causing its deceleration. Various kinds of sedatives can be distinguished, but the majority of them affect the neurotransmitter gamma-aminobutyric acid (GABA). In spite of the fact that each sedative acts in its own way, most produce relaxing effects by increasing GABA activity. This group is related to hypnotics. The term ''sedative'' describes drugs that serve to calm or relieve anxiety, whereas the term ''hypnotic'' describes drugs whose main purpose is to initiate, sustain, or lengthen sleep. Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness) they are often referred to collectively as ''sedative-hypnotic'' drugs. Sedatives can be used to produce an overly-calming effect ( alcohol being the m ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Major Tranquilizer
Antipsychotics, also known as neuroleptics, are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders. They are also the mainstay together with mood stabilizers in the treatment of bipolar disorder. Prior research has shown that use of any antipsychotic is associated with smaller brain tissue volumes, including white matter reduction and that this brain shrinkage is dose dependent and time dependent. A more recent controlled trial suggests that second generation antipsychotics combined with intensive psychosocial therapy may potentially prevent pallidal brain volume loss in first episode psychosis. The use of antipsychotics may result in many unwanted side effects such as involuntary movement disorders, gynecomastia, impotence, weight gain and metabolic syndrome. Long-term use can produce adverse effects such ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Antipsychotic
Antipsychotics, also known as neuroleptics, are a class of Psychiatric medication, psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders. They are also the mainstay together with mood stabilizers in the treatment of bipolar disorder. Prior research has shown that use of any antipsychotic is associated with smaller brain tissue volumes, including white matter reduction and that this brain shrinkage is dose dependent and time dependent. A more recent controlled trial suggests that second generation antipsychotics combined with intensive psychosocial therapy may potentially prevent pallidal brain volume loss in first episode psychosis. The use of antipsychotics may result in many unwanted side effects such as Extrapyramidal symptoms, involuntary movement disorders, gynecomastia, impotence, weight gain and metabolic syndrome. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Reserpine
Reserpine is a drug that is used for the treatment of high blood pressure, usually in combination with a thiazide diuretic or vasodilator. Large clinical trials have shown that combined treatment with reserpine plus a thiazide diuretic reduces mortality of people with hypertension. Although the use of reserpine as a solo drug has declined since it was first approved by the FDA in 1955, the combined use of reserpine and a thiazide diuretic or vasodilator is still recommended in patients who do not achieve adequate lowering of blood pressure with first-line drug treatment alone. The reserpine-hydrochlorothiazide combo pill was the 17th most commonly prescribed of the 43 combination antihypertensive pills available In 2012. The antihypertensive actions of reserpine are largely due to its antinoradrenergic effects, which are a result of its ability to deplete catecholamines (among other monoamine neurotransmitters) from peripheral sympathetic nerve endings. These substances are no ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rauwolfia
''Rauvolfia'' (sometimes spelled ''Rauwolfia'') is a genus of evergreen trees and shrubs, commonly known as devil peppers, in the family Apocynaceae. The genus is named to honor Leonhard Rauwolf. The genus can mainly be found in tropical regions of Africa, Asia, Latin America, and various oceanic islands. Spelling The International Code of Nomenclature for algae, fungi, and plants stipulates that the genus name was established by Carl Linnaeus in his 1753 book '' Species Plantarum'', which cites his earlier description which states in Botanical Latin that the name is dedicated "to Leonhard Rauwolf": "''Leon. Rauvolfio''". Although some subsequent authors hypercorrected the Classical Latin letter "v" to a modern "w", this is not accepted by the code of nomenclature. Chemical constituents ''Rauvolfia serpentina'', commonly known as Indian snakeroot or ''sarpagandha'', contains many indole alkaloids. Medicinal uses Reserpine is an alkaloid first isolated from '' R. serpent ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids xumuk.ru Alkaloids are produced by a large variety of organisms including , , Medicinal plant, plants, an ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tranquillity
Tranquillity (also spelled tranquility) is the quality or state of being tranquil; that is, calm, serene, and worry-free. The word tranquillity appears in numerous texts ranging from the religious writings of Buddhism, where the term ''passaddhi'' refers to tranquillity of the body, thoughts and consciousness on the path to enlightenment, to an assortment of policy and planning guidance documents, where interpretation of the word is typically linked to engagement with the natural environment. It is also famously used in the Preamble to the US Constitution - "insure domestic Tranquility". History The word tranquility dates back to the 12th century in the Old French word ''tranquilite'', meaning "peace" or "happiness", although the word's sense evolved in the late 14th century. However, the word still keeps its reference to the absence of disturbance and peacefulness. Benefits Psychological being in a tranquil or "restorative" environment allows individuals to take respite from the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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American And British English Spelling Differences
Despite the various List of dialects of English, English dialects spoken from country to country and within different regions of the same country, there are only slight regional variations in English orthography, the two most notable variations being British and American spelling. Many of Comparison of American and British English, the differences between American English, American and British English date back to a time before spelling standards were developed. For instance, some spellings seen as "American" today were once commonly used in Britain, and some spellings seen as "British" were once commonly used in the United States. A "British standard" began to emerge following the 1755 publication of Samuel Johnson's ''A Dictionary of the English Language'', and an "American standard" started following the work of Noah Webster and, in particular, his ''Webster's Dictionary, An American Dictionary of the English Language'', first published in 1828. Webster's efforts at spellin ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tension (psychological)
In psychology, stress is a feeling of emotional strain and pressure. Stress is a type of psychological pain. Small amounts of stress may be beneficial, as it can improve athletic performance, motivation and reaction to the environment. Excessive amounts of stress, however, can increase the risk of strokes, heart attacks, ulcers, and mental illnesses such as depression and also aggravation of a pre-existing condition. Stress can be external and related to the environment, but may also be caused by internal perceptions that cause an individual to experience anxiety or other negative emotions surrounding a situation, such as pressure, discomfort, etc., which they then deem stressful. Hans Selye (1974) proposed four variations of stress. On one axis he locates good stress (eustress) and bad stress (distress). On the other is over-stress (hyperstress) and understress (hypostress). Selye advocates balancing these: the ultimate goal would be to balance hyperstress and hypostress p ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |