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Tonix Pharmaceuticals
Tonix Pharmaceuticals (Tonix Pharmaceuticals Holding Corp.) is a pharmaceutical company based in Chatham, New jersey that focuses on drug repurposing, repurposed drugs for central nervous system conditions and as of 2020 was also pursuing a vaccine for Coronavirus disease 2019, COVID-19 and a biodefense project. History The company's predecessors were Tamandare Explorations Inc. which had been formed in 2007 as a mining wildcat vehicle focused on land in Nevada and the shares of which were traded Over-the-counter (finance), over the counter, and L & L Technologies, LLC, which had been formed in 1996 by Seth Lederman and Donald Landry to drug repurposing, repurpose drugs for CNS development. L&L had formed Janus Pharmaceuticals, Inc., which later became Vela Pharmaceuticals, Inc. to develop some of its inventions, and Vela returned those assets to L&L in 2006. L&L placed them in a subsidiary called Krele Pharmaceuticals, Inc., and that subsidiary and Tamandare Explorations Inc. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seth Lederman
Seth Lederman (born July 30, 1957) is a physician, scientist and specialty pharmaceuticals entrepreneur. He is a co-founder and the current President and Chairman of Tonix Pharmaceuticals, a specialty pharmaceutical product development and commercialization company. Biography Lederman earned his bachelor's degree in chemistry from Princeton University where he graduated ''cum laude'' in 1979. He completed his M.D. from Columbia University in 1983 and continued his training at the Columbia Presbyterian Medical Center until 1986. Lederman became an instructor at Columbia in 1985, assistant professor in 1988 and associate professor with tenure in 1996. From October 30, 2015, until November 1, 2016, he took a leave of absence, and left Columbia in April 2017. In addition to his research, he served as attending physician in the Edward Daniels Faulkner Arthritis Clinic at Columbia Presbyterian Hospital from 1988 to 1996 and served as associate attending physician at Columbia Presbyterian ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Repurposing
Drug repositioning (also called drug repurposing) involves the investigation of existing drugs for new therapeutic purposes. Repurposing achievements A number of successes have been achieved, the foremost including sildenafil (Viagra) for erectile dysfunction and pulmonary hypertension and thalidomide for leprosy and multiple myeloma. Clinical trials have been performed on posaconazole and ravuconazole for Chagas disease. Other antifungal agents clotrimazole and ketoconazole have been investigated for anti- trypanosome therapy. Successful repositioning of antimicrobials has led to the discovery of broad-spectrum therapeutics, which are effective against multiple infection types. In psychiatry, repurposed drugs are emerging as feasible options to treat severe mental disorders. Strategy Drug repositioning is a "universal strategy" for neglected diseases due to 1) reduced number of required clinical trial steps could reduce the time and costs for the medicine to reach ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |