Tell Me How I Die (2016 Film)
''Tell Me How I Die'' is a 2016 American psychological thriller film directed, produced, and co-written by D.J. Viola. The film stars Nathan Kress, Virginia Gardner, Kirby Bliss Blanton, Ryan Higa, Mark Furze, Ethan Peck, Mark Rolston and William Mapother. The film follows a group of college students who undergo a clinical drug trial, testing a memory enhancement drug. The side effects they soon experience shows them premonitions of their deaths. Plot The film opens with a man at home looking at drawings. He leaves his family in the house and commits suicide outside. One of the drawings is revealed to say "Kill yourself or I kill them all." In a speech, Dr. Layton (Mark Rolston) introduces the concept of A9913, a memory-enhancing drug created by Hallorann Pharmaceuticals. The drug is able to give individuals full memory recall, allowing them to fully relive their past memories. He meets with Dr. Jerrems (William Mapother), who has been working on the A9913 drug. Eighteen young ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Scott Benson
''Night in the Woods'' is a 2017 single-player adventure video game. It was developed by Infinite Fall, a studio founded by game designer Alec Holowka and animator/artist Scott Benson, and Secret Lab, an Australian studio, and published by Finji. The game was funded via the crowdfunding platform Kickstarter, where it eventually earned over 400% of its funding goal. It is a story-focused exploration game in which the player follows a young woman named Mae Borowski, who recently dropped out of college and has returned to her hometown to find unexpected changes. Prior to the release of ''Night in the Woods'', a companion game titled ''Longest Night'' was released in December 2013 by Holowka and Benson, along with co-writer Bethany Hockenberry. In December 2014, a second supplemental game was released, titled ''Lost Constellation''. The game was released on February 21, 2017 for Microsoft Windows, macOS, Linux, and PlayStation 4. The Xbox One version was released on December 1 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Phases Of Clinical Research
The phases of clinical research are the stages in which scientists conduct experiments with a health intervention to obtain sufficient evidence for a process considered effective as a medical treatment. For drug development, the clinical phases start with testing for safety in a few human subjects, then expand to many study participants (potentially tens of thousands) to determine if the treatment is effective. Clinical research is conducted on drug candidates, vaccine candidates, new medical devices, and new diagnostic assays. Summary Clinical trials testing potential medical products are commonly classified into four phases. The drug development process will normally proceed through all four phases over many years. If the drug successfully passes through Phases I, II, and III, it will usually be approved by the national regulatory authority for use in the general population. Phase IV trials are 'post-marketing' or 'surveillance' studies conducted to monitor safety over sever ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Films Shot In Los Angeles
A film also called a movie, motion picture, moving picture, picture, photoplay or (slang) flick is a work of visual art that simulates experiences and otherwise communicates ideas, stories, perceptions, feelings, beauty, or atmosphere through the use of moving images. These images are generally accompanied by sound and, more rarely, other sensory stimulations. The word "cinema", short for cinematography, is often used to refer to filmmaking and the film industry, and to the art form that is the result of it. Recording and transmission of film The moving images of a film are created by photographing actual scenes with a motion-picture camera, by photographing drawings or miniature models using traditional animation techniques, by means of CGI and computer animation, or by a combination of some or all of these techniques, and other visual effects. Before the introduction of digital production, series of still images were recorded on a strip of chemically sensitized ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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American Science Fiction Horror Films
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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2016 Horror Films
This is a list of horror films that were released in 2016. References {{DEFAULTSORT:Horror films of 2016 * 2016 File:2016 Events Collage.png, From top left, clockwise: Bombed-out buildings in Ankara following the 2016 Turkish coup d'état attempt; the impeachment trial of Brazilian President Dilma Rousseff; Damaged houses during the 2016 Nagorno-Karabakh ... 2016-related lists ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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2016 Films
2016 in film is an overview of events, including the highest-grossing films, award ceremonies, festivals, and a list of films released and deaths. Evaluation of the year In his article highlighting the best films of 2016, Richard Brody of ''The New Yorker'' stated, "Hollywood is the world's best money-laundering machine. It takes in huge amounts of money from the sale of mass-market commodities and cleanses some of it with the production of cinematic masterworks. Earning billions of dollars from C.G.I. comedies for children, superhero movies, sci-fi apocalypses, and other popular genres, the big studios channel some of those funds into movies by Wes Anderson, Sofia Coppola, Spike Lee, Martin Scorsese, James Gray, and other worthies. Sometimes there's even an overlap between the two groups of movies, as when Ryan Coogler made '' Creed'', or when Scorsese made the modernist horror instant-classic ''Shutter Island'', or when Clint Eastwood makes just about anything." Highest-gross ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Los Angeles Times
The ''Los Angeles Times'' (abbreviated as ''LA Times'') is a daily newspaper that started publishing in Los Angeles in 1881. Based in the LA-adjacent suburb of El Segundo since 2018, it is the sixth-largest newspaper by circulation in the United States. The publication has won more than 40 Pulitzer Prizes. It is owned by Patrick Soon-Shiong and published by the Times Mirror Company. The newspaper’s coverage emphasizes California and especially Southern California stories. In the 19th century, the paper developed a reputation for civic boosterism and opposition to labor unions, the latter of which led to the bombing of its headquarters in 1910. The paper's profile grew substantially in the 1960s under publisher Otis Chandler, who adopted a more national focus. In recent decades the paper's readership has declined, and it has been beset by a series of ownership changes, staff reductions, and other controversies. In January 2018, the paper's staff voted to unionize and final ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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The Hollywood Reporter
''The Hollywood Reporter'' (''THR'') is an American digital and print magazine which focuses on the Cinema of the United States, Hollywood film industry, film, television, and entertainment industries. It was founded in 1930 as a daily trade paper, and in 2010 switched to a weekly Wide-format printer, large-format print magazine with a revamped website. As of 2020, the day-to-day operations of the company are handled by Penske Media Corporation through a joint venture with Eldridge Industries. History Early years; 1930–1987 ''The Hollywood Reporter'' was founded in 1930 by William R. Wilkerson, William R. "Billy" Wilkerson (1890–1962) as Hollywood's first daily entertainment trade newspaper. The first edition appeared on September 3, 1930, and featured Wilkerson's front-page "Tradeviews" column, which became influential. The newspaper appeared Monday-to-Saturday for the first 10 years, except for a brief period, then Monday-to-Friday from 1940. Wilkerson used caustic articles ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Self-fulfilling Prophecy
A self-fulfilling prophecy is a prediction that comes true at least in part as a result of a person's or group of persons' belief or expectation that said prediction would come true. This suggests that people's beliefs influence their actions. The principle behind this phenomenon is that people create consequences regarding people or events, based on previous knowledge of the subject. There are three factors within an environment that can come together to influence the likelihood of a self-fulfilling prophecy becoming a reality: appearance, perception, and belief. When a phenomenon cannot be seen, appearance is what we rely upon when a self-fulfilling prophecy is in place. When it comes to a self-fulfilling prophecy there also must be a distinction "between 'brute and institutional' facts". The philosopher John Searle states the difference as "facts hatexist independently of any human institutions; institutional facts can only exist within institutions." There is an inability of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mustard Gas
Mustard gas or sulfur mustard is a chemical compound belonging to a family of cytotoxic and blister agents known as mustard agents. The name ''mustard gas'' is technically incorrect: the substance, when dispersed, is often not actually a gas, but is instead in the form of a fine mist of liquid droplets.https://www.acs.org/content/dam/acsorg/education/resources/highschool/chemmatters/gc-mustard-gas-personal-safety-and-natl-security.pdf Mustard gases form blisters on exposed skin and in the lungs, often resulting in prolonged illness ending in death. The active ingredient in typical mustard gas is the organosulfur compound bis(2-chloroethyl) sulfide. In the wider sense, compounds with the structural element are known as ''sulfur mustards'' and ''nitrogen mustards'', respectively. Such compounds are potent alkylating agents, which can interfere with several biological processes. History as chemical weapons As a chemical weapon, mustard gas was first used in World War I, and has ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sedative
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are CNS depressants and interact with brain activity causing its deceleration. Various kinds of sedatives can be distinguished, but the majority of them affect the neurotransmitter gamma-aminobutyric acid (GABA). In spite of the fact that each sedative acts in its own way, most produce relaxing effects by increasing GABA activity. This group is related to hypnotics. The term ''sedative'' describes drugs that serve to calm or relieve anxiety, whereas the term ''hypnotic'' describes drugs whose main purpose is to initiate, sustain, or lengthen sleep. Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness) they are often referred to collectively as ''sedative-hypnotic'' drugs. Sedatives can be used to produce an overly-calming effect ( alcohol being the m ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Déjà Vu
''Déjà vu'' ( , ; "already seen") is a French loanword for the phenomenon of feeling as though one has lived through the present situation before.Schnider, Armin. (2008). ''The Confabulating Mind: How the Brain Creates Reality''. Oxford University Press. pp. 167–168. Blom, Jan Dirk. (2010). ''A Dictionary of Hallucinations''. Springer. pp. 132-134. It is an illusion of memory whereby — despite a strong sense of recollection — the time, place, and context of the "previous" experience are uncertain or impossible. Approximately two-thirds of surveyed populations report experiencing déjà vu at least one time in their lives. The phenomenon manifests occasionally as a symptom of pre-seizure auras, and some researchers have associated chronic/frequent "pathological" déjà vu with neurological or psychiatric illness. Experiencing déjà vu has been correlated with higher socioeconomic status, better educational attainment, and lower ages. People who travel often, frequently ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |