TMEM33 MRNA Transcript Variants
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TMEM33 MRNA Transcript Variants
Transmembrane protein 33 is a protein that in humans, is encoded by the TMEM33 gene, also known as SHINC3. Another name for the TMEM33 protein is DB83. Gene In humans, this gene’s DNA location is the short arm of chromosome 4, loci position: 4p13. The genomic range is 41937502-41956213, spanning 18.7 kb, on the positive strand. Transmembrane protein 33 is ubiquitously expressed, but is particularly highly expressed in the blood, lymph nodes, bone, and adipose tissue. Promoter A promoter (genetics), promoter sequence upstream of TMEM33 is GXP_4428588. This 1069 base pair promoter sequence spans 41936535-41937603 on human chromosome 4. The promoter sequence overlaps with the 5' untranslated region, first coding exon, and first intron of the TMEM33 gene. Many different transcription factors are known to bind to this region. The most likely to bind transcription factors are expressed most in connective tissue (i.e. blood, adipose tissue, and bone), the immune system, and ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ...
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