|
Synteny
In genetics, the term synteny refers to two related concepts: * In classical genetics, ''synteny'' describes the physical co-localization of genetic loci on the same chromosome within an individual or species. * In current biology, ''synteny'' more commonly refers to ''colinearity'', i.e. conservation of blocks of order within two sets of chromosomes that are being compared with each other. These blocks are referred to as ''syntenic blocks''. The Encyclopædia Britannica gives the following description of synteny, using the modern definition: Etymology ''Synteny'' is a neologism meaning "on the same ribbon"; Ancient Greek, Greek: ', ''syn'' "along with" + ', ''tainiā'' "band". This can be interpreted classically as "on the same chromosome", or in the modern sense of having the same order of genes on two (homologous) strings of DNA (or chromosomes). : co-localization on a chromosome The classical concept is related to genetic linkage: Linkage between two loci is established ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Comparative Genomics
Comparative genomics is a field of biological research in which the genomic features of different organisms are compared. The genomic features may include the DNA sequence, genes, gene order, regulatory sequences, and other genomic structural landmarks. In this branch of genomics, whole or large parts of genomes resulting from genome projects are compared to study basic biological similarities and differences as well as evolutionary relationships between organisms. The major principle of comparative genomics is that common features of two organisms will often be encoded within the DNA that is evolutionarily conserved between them. Therefore, comparative genomic approaches start with making some form of alignment of genome sequences and looking for orthologous sequences (sequences that share a common ancestry) in the aligned genomes and checking to what extent those sequences are conserved. Based on these, genome and molecular evolution are inferred and this may in turn be put in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromosome
A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are the histones. These proteins, aided by chaperone proteins, bind to and condense the DNA molecule to maintain its integrity. These chromosomes display a complex three-dimensional structure, which plays a significant role in transcriptional regulation. Chromosomes are normally visible under a light microscope only during the metaphase of cell division (where all chromosomes are aligned in the center of the cell in their condensed form). Before this happens, each chromosome is duplicated ( S phase), and both copies are joined by a centromere, resulting either in an X-shaped structure (pictured above), if the centromere is located equatorially, or a two-arm structure, if the centromere is located distally. The joined copies are now called si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hox Gene
Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify the characteristics of 'position', ensuring that the correct structures form in the correct places of the body. For example, Hox genes in insects specify which appendages form on a segment (for example, legs, antennae, and wings in fruit flies), and Hox genes in vertebrates specify the types and shape of vertebrae that will form. In segmented animals, Hox proteins thus confer segmental or positional identity, but do not form the actual segments themselves. Studies on Hox genes in ciliated larvae have shown they are only expressed in future adult tissues. In larvae with gradual metamorphosis the Hox genes are activated in tissues of the larval body, generally in the trunk region, that will be maintained through metamorphosis. In larvae with complete metamorphosis the Hox genes are mainly express ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Happy Mapping
In genetics, HAPPY Mapping, first proposed by Paul H. Dear and Peter R. Cook in 1989, is a method used to study the linkage between two or more DNA sequences. According to thSingle Molecule Genomics Group it is ''"Mapping based on the analysis of approximately HAPloid DNA samples using the PolYmerase chain reaction"''. In genomics, HAPPY mapping can be applied to assess the synteny and orientation of various DNA sequences across a particular genome - the generation of a "genomic" map. As with linkage mapping, HAPPY mapping relies on the differential probability of two or more DNA sequences being separated. In genetic mapping, the probability of a recombination event between two genetic loci on the same chromosome A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are ... is directly proport ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BLAST
Blast or The Blast may refer to: * Explosion, a rapid increase in volume and release of energy in an extreme manner *Detonation, an exothermic front accelerating through a medium that eventually drives a shock front Film * ''Blast'' (1997 film), starring Andrew Divoff * ''Blast'' (2000 film), starring Liesel Matthews * ''Blast'' (2004 film), an action comedy film * ''Blast!'' (1972 film) or ''The Final Comedown'', an American drama * ''BLAST!'' (2008 film), a documentary about the BLAST telescope * '' A Blast'', a 2014 film directed by Syllas Tzoumerkas Magazines * ''Blast'' (magazine), a 1914–15 literary magazine of the Vorticist movement * ''Blast'' (U.S. magazine), a 1933–34 American short-story magazine * ''The Blast'' (magazine), a 1916–17 American anarchist periodical Music * Blast (American band), a hardcore punk band * Blast (Russian band), an indie band * ''Blast'' (album), by Holly Johnson, 1989 * ''The Blast'' (album), by Yuvan Shankar Raja, 1999 * " ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Contig
A contig (from ''contiguous'') is a set of overlapping DNA segments that together represent a consensus region of DNA.Gregory, S. ''Contig Assembly''. Encyclopedia of Life Sciences, 2005. In bottom-up sequencing projects, a contig refers to overlapping sequence data ( reads); in top-down sequencing projects, contig refers to the overlapping clones that form a physical map of the genome that is used to guide sequencing and assembly.Dear, P. H. ''Genome Mapping''. Encyclopedia of Life Sciences, 2005. . Contigs can thus refer both to overlapping DNA sequences and to overlapping physical segments (fragments) contained in clones depending on the context. Original definition of contig In 1980, Staden wrote: ''In order to make it easier to talk about our data gained by the shotgun method of sequencing we have invented the word "contig". A contig is a set of gel readings that are related to one another by overlap of their sequences. All gel readings belong to one and only one con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phylogenetic
In biology, phylogenetics (; from Greek φυλή/ φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups of organisms. These relationships are determined by Computational phylogenetics, phylogenetic inference methods that focus on observed heritable traits, such as DNA sequences, protein amino acid sequences, or morphology. The result of such an analysis is a phylogenetic tree—a diagram containing a hypothesis of relationships that reflects the evolutionary history of a group of organisms. The tips of a phylogenetic tree can be living taxa or fossils, and represent the "end" or the present time in an evolutionary lineage. A phylogenetic diagram can be rooted or unrooted. A rooted tree diagram indicates the hypothetical common ancestor of the tree. An unrooted tree diagram (a network) makes no assumption about the ancestral line, and does ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trait (biology)
A phenotypic trait, simply trait, or character state is a distinct variant of a phenotypic characteristic of an organism; it may be either inherited or determined environmentally, but typically occurs as a combination of the two.Lawrence, Eleanor (2005) ''Henderson's Dictionary of Biology''. Pearson, Prentice Hall. For example, having eye color is a ''character'' of an organism, while blue, brown and hazel versions of eye colour are ''traits''. The term ''trait'' is generally used in genetics, often to describe phenotypic expression of different combinations of alleles in different individual organisms within a single population, such as the famous purple vs. white flower coloration in Gregor Mendel's pea plants. By contrast, in systematics, the term is ''character state'' is employed to describe features that represent fixed diagnostic differences among taxa, such as the absence of tails in great apes, relative to other primate groups. Definition A phenotypic trait is a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enterobacteriales
Enterobacterales is an order of Gram-negative bacteria, Gram-negative, non-spore forming, Facultative anaerobic organism, facultatively anaerobic, rod-shaped bacteria with the class Gammaproteobacteria. The type genus of this order is ''Enterobacter.'' The name Enterobacterales is derived from the Latin term ''Enterobacter'', referring the type genus of the order and the suffix "-ales", an ending used to denote an order. Together, Enterobacterales refers to an order whose nomenclatural type is the genus ''Enterobacter''. Historical Identification and Systematics Enterobacterales was proposed in 2005 under the name "Enterobacteriales". However, the name "Enterobacteriales" was not validated according to the rules of the ''International Code of Nomenclature of Prokaryotes,'' thus it lacked standing in nomenclature, so the name was written in parentheses. "Enterobacteriales" was a monotypic order, containing only the family ''Enterobacteriaceae'', and shared its type genus ''Esch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyphomicrobiales
The ''Hyphomicrobiales'' are an order of Gram-negative Alphaproteobacteria. The rhizobia, which fix nitrogen and are symbiotic with plant roots, appear in several different families. The four families ''Nitrobacteraceae'', ''Hyphomicrobiaceae'', '' Phyllobacteriaceae'', and ''Rhizobiaceae'' contain at least several genera of nitrogen-fixing, legume-nodulating, microsymbiotic bacteria. Examples are the genera ''Bradyrhizobium'' and ''Rhizobium''. Species of the ''Methylocystaceae'' are methanotrophs; they use methanol (CH3OH) or methane (CH4) as their sole energy and carbon sources. Other important genera are the human pathogens ''Bartonella'' and ''Brucella'', as well as ''Agrobacterium'' (useful in genetic engineering). Taxonomy Accepted families * ''Aestuariivirgaceae'' Li ''et al''. 2019 * '' Afifellaceae'' Hördt ''et al''. 2020 * '' Ahrensiaceae'' Hördt ''et al''. 2020 * ''Alsobacteraceae'' Sun ''et al''. 2018 * ''Amorphaceae'' Hördt ''et al''. 2020 * ''Ancalomicrobia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brachypodium
''Brachypodium'' is a genus of plants in the grass family, widespread across much of Africa, Eurasia, and Latin America. The genus is classified in its own tribe Brachypodieae. Flimsy upright stems form tussocks. Flowers appear in compact spike-like racemes with 5-25 flowers on each short-stalked spikelet in summer. Leaves are flat or curved. According to an October 18, 2010 issue of "Nature Online" Laura Longo, an archeologist at University of Siena in Italy found evidence of ''Brachypodium'' and cattail ('' Typha'' spp.) residues on prehistoric human grinding tools dated 28,000 years ago from Bilancino in central Italy. A related article authored by Anna Revedin, Biancamaria Aranguren, Roberto Becattini, Laura Longo, Emanuele Marconi, Marta Mariotti Lippi, Natalia Skakun, Andrey Sinitsyn, Elena Spiridonova, and Jiří Svoboda, was contemporaneously published in the Proceedings of the National Academy of Sciences of the United States of America and clarifies that the grain r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
