Synchrotron Radiation Source
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Synchrotron Radiation Source
The Synchrotron Radiation Source (SRS) at the Daresbury Laboratory in Cheshire, England was the first second-generation synchrotron radiation source to produce X-rays. The research facility provided synchrotron radiation to a large number of experimental stations and had an operating cost of approximately £20 million per annum. SRS had been operated by the Science and Technology Facilities Council. The SRS was closed on 4 August 2008 after 28 years of operation. History Following the closure of the NINA synchrotron, construction of the facility commenced in 1975 and the first experiments were completed using the facility by 1981. In 1986 the storage ring was upgraded with additional focusing to increase the output brightness, the new 'lattice' being termed the HBL (High Brightness Lattice). Design and evolution Like all second-generation sources, the SRS was designed to produce synchrotron radiation principally from its dipole magnets, but the initial design foresaw the use of ...
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Synchrotron Radiation Source (SRS), Daresbury Laboratory - Geograph
The Synchrotron Radiation Source (SRS) at the Daresbury Laboratory in Cheshire, England was the first second-generation synchrotron radiation source to produce X-rays. The research facility provided synchrotron radiation to a large number of experimental stations and had an operating cost of approximately £20 million per annum. SRS had been operated by the Science and Technology Facilities Council. The SRS was closed on 4 August 2008 after 28 years of operation. History Following the closure of the NINA synchrotron, construction of the facility commenced in 1975 and the first experiments were completed using the facility by 1981. In 1986 the storage ring was upgraded with additional focusing to increase the output brightness, the new 'lattice' being termed the HBL (High Brightness Lattice). Design and evolution Like all second-generation sources, the SRS was designed to produce synchrotron radiation principally from its dipole magnets, but the initial design foresaw the use ...
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CERN
The European Organization for Nuclear Research, known as CERN (; ; ), is an intergovernmental organization that operates the largest particle physics laboratory in the world. Established in 1954, it is based in a northwestern suburb of Geneva, on the France–Switzerland border. It comprises 23 member states, and Israel (admitted in 2013) is currently the only non-European country holding full membership. CERN is an official United Nations General Assembly observer. The acronym CERN is also used to refer to the laboratory; in 2019, it had 2,660 scientific, technical, and administrative staff members, and hosted about 12,400 users from institutions in more than 70 countries. In 2016, CERN generated 49 petabytes of data. CERN's main function is to provide the particle accelerators and other infrastructure needed for high-energy physics research — consequently, numerous experiments have been constructed at CERN through international collaborations. CERN is the site of the ...
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Diamond Light Source
Diamond Light Source (or Diamond) is the UK's national synchrotron light source science facility located at the Harwell Science and Innovation Campus in Oxfordshire. Its purpose is to produce intense beams of light whose special characteristics are useful in many areas of scientific research. In particular it can be used to investigate the structure and properties of a wide range of materials from proteins (to provide information for designing new and better drugs), and engineering components (such as a fan blade from an aero-engine) to conservation of archeological artifacts (for example Henry VIII's flagship the Mary Rose). There are more than 50 light sources across the world. With an energy of 3 GeV, Diamond is a medium energy synchrotron currently operating with 32 beamlines. Design, construction and finance The Diamond synchrotron is the largest UK-funded scientific facility to be built in the UK since the Nimrod proton synchrotron which was sited at the Rutherfor ...
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Messenger RNA
In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein. mRNA is created during the process of transcription, where an enzyme (RNA polymerase) converts the gene into primary transcript mRNA (also known as pre-mRNA). This pre-mRNA usually still contains introns, regions that will not go on to code for the final amino acid sequence. These are removed in the process of RNA splicing, leaving only exons, regions that will encode the protein. This exon sequence constitutes mature mRNA. Mature mRNA is then read by the ribosome, and, utilising amino acids carried by transfer RNA (tRNA), the ribosome creates the protein. This process is known as translation. All of these processes form part of the central dogma of molecular biology, which describes the flow of genetic information in a biological system. As in DNA, genetic inf ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ...
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Ribosome
Ribosomes ( ) are macromolecular machines, found within all cells, that perform biological protein synthesis (mRNA translation). Ribosomes link amino acids together in the order specified by the codons of messenger RNA (mRNA) molecules to form polypeptide chains. Ribosomes consist of two major components: the small and large ribosomal subunits. Each subunit consists of one or more ribosomal RNA (rRNA) molecules and many ribosomal proteins (RPs or r-proteins). The ribosomes and associated molecules are also known as the ''translational apparatus''. Overview The sequence of DNA that encodes the sequence of the amino acids in a protein is transcribed into a messenger RNA chain. Ribosomes bind to messenger RNAs and use their sequences for determining the correct sequence of amino acids to generate a given protein. Amino acids are selected and carried to the ribosome by transfer RNA (tRNA) molecules, which enter the ribosome and bind to the messenger RNA chain via an anti-c ...
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Venki Ramakrishnan
Venkatraman Ramakrishnan (born 1952) is an Indian-born British and American structural biologist who shared the 2009 Nobel Prize in Chemistry with Thomas A. Steitz and Ada Yonath, "for studies of the structure and function of the ribosome". Since 1999, he has worked as a group leader at the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) on the Cambridge Biomedical Campus, UK and is a Fellow of Trinity College, Cambridge. He served as President of the Royal Society from 2015 to 2020. Education and early life Ramakrishnan was born in a Tamil family of Chidambaram in Cuddalore district of Tamil Nadu, India to C. V. Ramakrishnan and Rajalakshmi Ramakrishnan on 1 April 1952. Both his parents were scientists, and his father was head of the Department of Biochemistry at the Maharaja Sayajirao University of Baroda. At the time of his birth, Ramakrishnan's father was away from India doing postdoctoral research with David E. Green at the University of Wisconsi ...
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Adenosine Triphosphate
Adenosine triphosphate (ATP) is an organic compound that provides energy to drive many processes in living cells, such as muscle contraction, nerve impulse propagation, condensate dissolution, and chemical synthesis. Found in all known forms of life, ATP is often referred to as the "molecular unit of currency" of intracellular energy transfer. When consumed in metabolic processes, it converts either to adenosine diphosphate (ADP) or to adenosine monophosphate (AMP). Other processes regenerate ATP. The human body recycles its own body weight equivalent in ATP each day. It is also a precursor to DNA and RNA, and is used as a coenzyme. From the perspective of biochemistry, ATP is classified as a nucleoside triphosphate, which indicates that it consists of three components: a nitrogenous base (adenine), the sugar ribose, and the Polyphosphate, triphosphate. Structure ATP consists of an adenine attached by the 9-nitrogen atom to the 1′ carbon atom of a sugar (ribose), which i ...
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John E
John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second Epistle of John, often shortened to 2 John * Third Epistle of John, often shortened to 3 John People * John the Baptist (died c. AD 30), regarded as a prophet and the forerunner of Jesus Christ * John the Apostle (lived c. AD 30), one of the twelve apostles of Jesus * John the Evangelist, assigned author of the Fourth Gospel, once identified with the Apostle * John of Patmos, also known as John the Divine or John the Revelator, the author of the Book of Revelation, once identified with the Apostle * John the Presbyter, a figure either identified with or distinguished from the Apostle, the Evangelist and John of Patmos Other people with the given name Religious figures * John, father of Andrew the Apostle and Saint Peter * Pope J ...
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Beam Emittance
In accelerator physics, emittance is a property of a charged particle beam. It refers to the area occupied by the beam in a position-and-momentum phase space. Each particle in a beam can be described by its position and momentum along each of three orthogonal axes, for a total of six position and momentum coordinates. When the position and momentum for a single axis are plotted on a two dimensional graph, the average spread of the coordinates on this plot are the emittance. As such, a beam will have three emittances, one along each axis, which can be described independently. As particle momentum along an axis is usually described as an angle relative to that axis, an area on a position-momentum plot will have dimensions of length × angle (for example, millimeters × milliradian). Emittance is important for analysis of particle beams. As long as the beam is only subjected to conservative forces, Liouville's Theorem shows that emittance is a conserved quantity. If t ...
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Daresbury Laboratory
Daresbury Laboratory is a scientific research laboratory based at Sci-Tech Daresbury campus near Daresbury in Halton, Cheshire, England. The laboratory began operations in 1962 and was officially opened on 16 June 1967 as the Daresbury Nuclear Physics Laboratory by the then Prime Minister of United Kingdom, Harold Wilson. It was the second national laboratory established by the British National Institute for Research in Nuclear Science, following the Rutherford High Energy Laboratory (now Rutherford Appleton Laboratory). It is operated by the Science and Technology Facilities Council, part of UK Research and Innovation. As of 2018, it employs around 300 staff, with Paul Vernon appointed as director in November 2020, taking over from Professor Susan Smith who had been director from 2012. Description Daresbury Laboratory carries out research in fields such as accelerator science, bio-medicine, physics, chemistry, materials, engineering and computational science. Its facilities ar ...
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Quadrupoles
A quadrupole or quadrapole is one of a sequence of configurations of things like electric charge or current, or gravitational mass that can exist in ideal form, but it is usually just part of a multipole expansion of a more complex structure reflecting various orders of complexity. Mathematical definition The quadrupole moment tensor ''Q'' is a rank-two tensor—3×3 matrix. There are several definitions, but it is normally stated in the traceless form (i.e. Q_ + Q_ + Q_ = 0). The quadrupole moment tensor has thus nine components, but because of transposition symmetry and zero-trace property, in this form only five of these are independent. For a discrete system of \ell point charges or masses in the case of a gravitational quadrupole, each with charge q_\ell, or mass m_\ell, and position \vec_\ell = \left(r_, r_, r_\right) relative to the coordinate system origin, the components of the ''Q'' matrix are defined by: : Q_ = \sum_\ell q_\ell\left(3r_ r_ - \left\, \vec_\ell \righ ...
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