Suzanne Cory
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Suzanne Cory
Suzanne Cory (born 11 March 1942) is an Australian molecular biologist. She has worked on the genetics of the immune system and cancer and has lobbied her country to invest in science. She is married to fellow scientist Jerry Adams, also a WEHI scientist, whom she met while studying for her PhD at the University of Cambridge, England. Education and personal life Suzanne Cory was raised in the Kew, Melbourne, Kew suburbs of Melbourne, Australia. She attended Canterbury Girls' Secondary College, followed by University High School, Melbourne. Her further education includes undergraduate studies at the University of Melbourne and earning a PhD from the MRC Laboratory of Molecular Biology (LMB) in Cambridge, England. Cory attended the LMB at the same time as the Nobel Prize winners Francis Crick, known for his co-discovery of the structure of DNA, and Frederick Sanger, who revolutionised nucleic acid sequencing. While obtaining her PhD, Cory used Sanger's RNA sequencing technique ...
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Australia
Australia, officially the Commonwealth of Australia, is a Sovereign state, sovereign country comprising the mainland of the Australia (continent), Australian continent, the island of Tasmania, and numerous List of islands of Australia, smaller islands. With an area of , Australia is the largest country by area in Oceania and the world's List of countries and dependencies by area, sixth-largest country. Australia is the oldest, flattest, and driest inhabited continent, with the least fertile soils. It is a Megadiverse countries, megadiverse country, and its size gives it a wide variety of landscapes and climates, with Deserts of Australia, deserts in the centre, tropical Forests of Australia, rainforests in the north-east, and List of mountains in Australia, mountain ranges in the south-east. The ancestors of Aboriginal Australians began arriving from south east Asia approximately Early human migrations#Nearby Oceania, 65,000 years ago, during the Last Glacial Period, last i ...
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University Of Geneva
The University of Geneva (French: ''Université de Genève'') is a public research university located in Geneva, Switzerland. It was founded in 1559 by John Calvin as a theological seminary. It remained focused on theology until the 17th century, when it became a center for enlightenment scholarship. Today, it is the third largest university in Switzerland by number of students. In 1873, it dropped its religious affiliations and became officially secular. In 2009, the University of Geneva celebrated the 450th anniversary of its founding. Almost 40% of the students come from foreign countries. The university holds and actively pursues teaching, research, and community service as its primary objectives. In 2016, it was ranked 53rd worldwide by the Shanghai Academic Ranking of World Universities, 89th by the QS World University Rankings, and 131st in the Times Higher Education World University Ranking. UNIGE is a member of the League of European Research Universities (includi ...
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Australian Academy Of Science
The Australian Academy of Science was founded in 1954 by a group of distinguished Australians, including Australian Fellows of the Royal Society of London. The first president was Sir Mark Oliphant. The academy is modelled after the Royal Society and operates under a Royal Charter; as such, it is an independent body, but it has government endorsement. The Academy Secretariat is in Canberra, at the Shine Dome. The objectives of the academy are to promote science and science education through a wide range of activities. It has defined four major program areas: :* Recognition of outstanding contributions to science :* Education and public awareness :* Science policy :* International relations The academy also runs the 22 National Committees for Science which provide a forum to discuss issues relevant to all the scientific disciplines in Australia. Origins The Australian National Research Council (ANRC) was established in 1919 for the purpose of representing Australia on the In ...
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Lymphoma
Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell). In current usage the name usually refers to just the cancerous versions rather than all such tumours. Signs and symptoms may include enlarged lymph nodes, fever, drenching sweats, unintended weight loss, itching, and constantly feeling tired. The enlarged lymph nodes are usually painless. The sweats are most common at night. Many subtypes of lymphomas are known. The two main categories of lymphomas are the non-Hodgkin lymphoma (NHL) (90% of cases) and Hodgkin lymphoma (HL) (10%). The World Health Organization (WHO) includes two other categories as types of lymphoma – multiple myeloma and immunoproliferative diseases. Lymphomas and leukemias are a part of the broader group of tumors of the hematopoietic and lymphoid tissues. Risk factors for Hodgkin lymphoma include infection with Epstein–Barr virus and a history of the disease in the family. Risk factors for common ...
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms ( palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''medical oncology''. The term ''chemotherapy'' has come to connote non-specific usage of intracellular poisons to inhibit mitosis (cell division) or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals (signal transduction). The development of therapies with specific molecular or genetic targets, wh ...
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BH3 Interacting-domain Death Agonist
The BH3 interacting-domain death agonist, or BID, gene is a pro-apoptotic member of the Bcl-2 protein family. Bcl-2 family members share one or more of the four characteristic domains of homology entitled the Bcl-2 homology (BH) domains (named BH1, BH2, BH3 and BH4), and can form hetero- or homodimers. Bcl-2 proteins act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Interactions BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into organelle membranes, primarily the outer mitochondrial membrane. Bax is believed to interact with, and induce the opening of the mitochondrial voltage-dependent anion channel, VDAC. Alternatively, growing evidence suggest that activated Bax and/or Bak form an oligomeric pore, MAC in the outer membrane. This results in the release of cytochrome c and other pr ...
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