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Sucrets
Dyclonine (Dyclocaine) is an oral anaesthetic that is the active ingredient of Sucrets, an over-the-counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt. History The product Sucrets was introduced in Baltimore, Maryland, by Sharp & Dohme in 1932. In 1966 the Federal Trade Commission ordered Merck and Company to discontinue the false claims of germ-killing and pain-relieving properties for its Sucrets and Children's Sucrets throat lozenges. In 1977, it was acquired by Beecham, later merging with SmithKline Beckman in 1989 to form SmithKline Beecham. By 1994 the brand switched from a metal container to a plastic container. SmithKline Beecham, after announcing a merger with GlaxoWellcome to form GlaxoSmithKline, sold the brand in 2000 to Insight Pharmaceuticals. In 2011, Sucrets reintroduced their product back into the familiar tin due to popular demand and nostalgia. S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beecham (pharmaceutical Company)
The Beecham Group plc was a British pharmaceutical company. It was once a constituent of the FTSE 100 Index. Beecham, after having merged with American pharmaceutical company SmithKline Beckman to become SmithKline Beecham, merged with Glaxo Wellcome to become GlaxoSmithKline (GSK). GSK still uses the Beechams brand name in the UK for its over-the-counter cold and flu relief products. Early history Beecham began as the family business of Thomas Beecham (1820–1907), a chemist. (Beecham would become the grandfather of music conductor Thomas Beecham, 1879–1961). As a boy, Beecham worked as a shepherd, selling herbal remedies as a sideline. He later became a travelling salesman or peddler full time. His first product was Beecham's Pills, a laxative, in 1842. Subsequent success enabled him to open a shop in Wigan in 1847. Beecham opened its first factory in 1849 in St Helens, Lancashire, for the rapid production of medicines. Under his son, Sir Joseph Beecham, 1st Barone ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Throat Lozenge
A throat lozenge (also known as a cough drop, sore throat sweet, troche, cachou, pastille or cough sweet) is a small, typically medicated tablet intended to be dissolved slowly in the mouth to temporarily stop coughs, lubricate, and soothe irritated tissues of the throat (usually due to a sore throat or strep throat), possibly from the common cold or influenza. Cough tablets have taken the name lozenge, based on their original shape, a diamond. Ingredients Lozenges may contain benzocaine, an anaesthetic, or eucalyptus oil. Non-menthol throat lozenges generally use either zinc gluconate glycine or pectin as an oral demulcent. Several brands of throat lozenges contain dextromethorphan. Other varieties such as Halls contain menthol, peppermint oil and/or spearmint as their active ingredient(s). Honey lozenges are also available. The purpose of the throat lozenge is to calm the irritation that may be felt in the throat while swallowing, breathing, or even drinking certain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SmithKline Beckman
Smith, Kline & French (SKF) was an American pharmaceutical company. History In 1830, John K. Smith opened a drugstore in Philadelphia, and his younger brother, George, joined him in 1841 to form John K Smith & Co. In 1865, Mahlon Kline joined ''Smith and Shoemaker'', as John K Smith and Co had become in the meantime, as a bookkeeper. In 1875, he took on additional responsibilities as a salesman and added many new and large accounts, as a reward the company, Mahlon K Smith and Company, was renamed into Smith, Kline and Company. In 1891, Smith, Kline and Company acquired French, Richards and Company, founded in 1844 by Clayton French and William Richards, which provided the company with a greater portfolio of consumer brands. In 1929 ''Smith, Kline and French Company'' was renamed into ''Smith Kline and French Laboratories'' and the company put more focus on research in order to sustain its business. In 1932, SKF chemist Gordon Alles was awarded a patent for amphetamine. In 196 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merck & Co
Merck & Co., Inc. is an American multinational pharmaceutical company headquartered in Rahway, New Jersey, and is named for Merck Group, founded in Germany in 1668, of whom it was once the American arm. The company does business as Merck Sharp & Dohme or MSD outside the United States and Canada. Merck & Co. was originally established as the American affiliate of Merck Group in 1891. Merck develops and produces medicines, vaccines, biologic therapies and animal health products. It has multiple blockbuster drugs or products each with 2020 revenues including cancer immunotherapy, anti-diabetic medication and vaccines against HPV and chickenpox. The company is ranked 71st on the 2022 ''Fortune'' 500 and 87th on the 2022 ''Forbes'' Global 2000, both based on 2021 revenues. Products The company develops medicines, vaccines, biologic therapies and animal health products. In 2020, the company had 6 blockbuster drugs or products, each with over $1 billion in revenue: ''Keytruda' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Piceol Ethers
Piceol is a phenolic compound found in the needles and in mycorrhizal roots of Norway spruces ('' Picea abies''). Picein is the glucoside of piceol. Uses Piceol is used in the synthesis of several pharmaceutical drugs including octopamine, sotalol, bamethan, and dyclonine. Piceol can be used to make acetaminophen by oxime formation with hydroxylamine and subsequent Beckmann rearrangement in acid. Anticonvulsants are also possible by Mannich reaction: Metabolism Diprenylated derivatives of piceol can be isolated from ''Ophryosporus macrodon''. 4-Hydroxyacetophenone monooxygenase is an enzyme that transforms piceol into O-acetylhydroquinone. This enzyme is found in ''Pseudomonas fluorescens''. See also * Paroxypropione, where the acetyl group is replaced by a propionyl Propionic acid (, from the Greek words πρῶτος : ''prōtos'', meaning "first", and πίων : ''píōn'', meaning "fat"; also known as propanoic acid) is a naturally occurring carboxylic aci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antiseptics
An antiseptic (from Greek ἀντί ''anti'', "against" and σηπτικός ''sēptikos'', "putrefactive") is an antimicrobial substance or compound that is applied to living tissue/skin to reduce the possibility of infection, sepsis, or putrefaction. Antiseptics are generally distinguished from ''antibiotics'' by the latter's ability to safely destroy bacteria within the body, and from ''disinfectants'', which destroy microorganisms found on non-living objects. Antibacterials include antiseptics that have the proven ability to act against bacteria. Microbicides which destroy virus particles are called viricides or antivirals. Antifungals, also known as antimycotics, are pharmaceutical fungicides used to treat and prevent mycosis (fungal infection). Surgery The widespread introduction of antiseptic surgical methods was initiated by the publishing of the paper '' Antiseptic Principle of the Practice of Surgery'' in 1867 by Joseph Lister, which was inspired by Louis Pasteur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hexylresorcinol
Hexylresorcinol is an organic compound with local anaesthetic, antiseptic, and anthelmintic properties. It is available for use topically on small skin infections, or as an ingredient in throat lozenges. It is marketed as S.T.37 by Numark Laboratories, Inc. (in a 0.1% solution) for oral pain relief and as an antiseptic. Sytheon Ltd., USA markets hexylresorcinol (trade named Synovea HR). Johnson & Johnson uses hexylresorcinol in its Neutrogena, Aveno, and RoC skincare products as an anti-aging cream. Hexylresorcinol has been used commercially by many cosmetic and personal care companies, such as Mary Kay, Clarins, Unilever, Murad, Facetheory, Arbonne, and many small and large companies. As an anthelmintic, hexylresorcinol was sold under the brand Crystoids. A study published in ''Chemical Research in Toxicology'' shows that 4-hexylresorcinol used as a food additive (E-586) exhibits some estrogenic activity, i.e. resembles action of the female sex hormone estrogen. However, rec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insight Pharmaceuticals
Insight is the understanding of a specific cause and effect within a particular context. The term insight can have several related meanings: *a piece of information *the act or result of understanding the inner nature of things or of seeing intuitively (called noesis in Greek) *an introspection *the power of acute observation and deduction, discernment, and perception, called intellection or noesis *An understanding of cause and effect based on the identification of relationships and behaviors within a model, context, or scenario (see artificial intelligence) An insight that manifests itself suddenly, such as understanding how to solve a difficult problem, is sometimes called by the German word '' Aha-Erlebnis''. The term was coined by the German psychologist and theoretical linguist Karl Bühler. It is also known as an epiphany, eureka moment or (for cross word solvers) the penny dropping moment (PDM). Sudden sickening realisations often identify a problem rather than solving ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GlaxoSmithKline
GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the tenth largest pharmaceutical company and #294 on the 2022 ''Fortune'' Global 500, ranked behind other pharmaceutical companies China Resources, Sinopharm, Johnson & Johnson, Pfizer, Roche, AbbVie, Novartis, Bayer, and Merck. The company has a primary listing on the London Stock Exchange and is a constituent of the FTSE 100 Index. , it had a market capitalisation of £70 billion, the eighth largest on the London Stock Exchange. It has a secondary listing on the New York Stock Exchange. The company developed the first malaria vaccine, RTS,S, which it said in 2014 it would make available for five percent above cost. Legacy products developed at GSK include several listed in the World Health Organization's List of Essential Medicines, such ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
USA Today
''USA Today'' (stylized in all uppercase) is an American daily middle-market newspaper and news broadcasting company. Founded by Al Neuharth on September 15, 1982, the newspaper operates from Gannett's corporate headquarters in Tysons, Virginia. Its newspaper is printed at 37 sites across the United States and at five additional sites internationally. The paper's dynamic design influenced the style of local, regional, and national newspapers worldwide through its use of concise reports, colorized images, informational graphics, and inclusion of popular culture stories, among other distinct features. With an average print circulation of 159,233 as of 2022, a digital-only subscriber base of 504,000 as of 2019, and an approximate daily readership of 2.6 million, ''USA Today'' is ranked as the first by circulation on the list of newspapers in the United States. It has been shown to maintain a generally center-left audience, in regards to political persuasion. ''USA Today'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plastic Container
Plastic containers are containers made exclusively or partially of plastic. Plastic containers are ubiquitous either as single-use or reuseable/durable plastic cups, plastic bottles, plastic bags, foam food containers, Tupperware, plastic tubes, clamshells, cosmetic containers, up to intermediate bulk containers and various types of containers made of corrugated plastic. The entire packaging industry heavily depends on plastic containers or containers with some plastic content (e.g. plastic coating or when made of composite material), besides paperboard and other materials. Food storage nowadays relies mainly on plastic food storage containers. A basic but important distinction is between single-use / disposable and multi-use / durable containers. The former makes up a notable portion of the global plastic waste (e.g. toothpaste tubs, food delivery foam containers, most plastic bottles, etc.). Because of the multitude of container applications, the types of plastic var ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
