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Southern Research Institute
Southern Research is a not-for-profit US 501(c)(3) research organization that conducts basic and applied research for commercial and non-commercial organizations across four divisions: Drug Development, Drug Discovery, Energy & Environment, and Engineering. History Southern Research was founded in Birmingham, Alabama, on October 11, 1941 by Thomas Martin as the Alabama Research Institute. Although Martin was named chairman of the newly chartered organization in December, 1941, activities were put on hold in the aftermath of the attack on Pearl Harbor and the beginning of US involvement in World War II. Two years later, in December 1943, with a promise of support from the Alabama Power Company, Martin reengaged the Alabama's industrial leaders and received over $100,000 in philanthropic donations. Alabama Power Company pledged an additional US$15,000 per year for five years, $75,000 total, and this was enough for the organization to finance laboratory space and hire researchers an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Not-for-profit
A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in contrast with an entity that operates as a business aiming to generate a profit for its owners. A nonprofit is subject to the non-distribution constraint: any revenues that exceed expenses must be committed to the organization's purpose, not taken by private parties. An array of organizations are nonprofit, including some political organizations, schools, business associations, churches, social clubs, and consumer cooperatives. Nonprofit entities may seek approval from governments to be tax-exempt, and some may also qualify to receive tax-deductible contributions, but an entity may incorporate as a nonprofit entity without securing tax-exempt status. Key aspects of nonprofits are accountability, trustworthiness, honesty, and openness to eve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lomustine
Lomustine (INN); abbreviated as CCNU; original brand name CeeNU, now marketed as Gleostine) is an alkylating nitrosourea compound used in chemotherapy. It is closely related to semustine and is in the same family as streptozotocin. It is a highly lipid-soluble drug, thus it crosses the blood–brain barrier. This property makes it ideal for treating brain tumors, which is its primary use, although it is also used to treat Hodgkin lymphoma as a second-line option. Lomustine has a long time to nadir (the time when white blood cells reach their lowest number). Unlike carmustine, lomustine is administered orally. It is a bifunctional alkylating agent, alkylates both DNA and RNA, has the ability to created interstrand cross-links (ICLs) in DNA. As with other nitrosoureas, it may also inhibit several key enzymatic processes by carbamoylation of amino acids in proteins. Lomustine is cell-cycle nonspecific. It has also been used in veterinary practice as a treatment for mast cell tum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carmustine
Carmustine, sold under the brand name BiCNU among others, is a medication used mainly for chemotherapy. It is a nitrogen mustard β-chloro- nitrosourea compound used as an alkylating agent. Description Carmustine is an orange-yellow solid medication used mainly for chemotherapy. It is a nitrogen mustard β-chloro- nitrosourea compound. Mechanism of action As an alkylating agent, carmustine can form interstrand crosslinks in DNA, which prevents DNA replication and DNA transcription. Uses Carmustine is used as an alkylating agent to treat several types of brain cancer including glioma, glioblastoma multiforme, medulloblastoma and astrocytoma), multiple myeloma, and lymphoma (Hodgkin's and non-Hodgkin). Carmustine is sometimes used in conjunction with alkyl guanine transferase (AGT) inhibitors, such as ''O''6-benzylguanine. The AGT-inhibitors increase the efficacy of carmustine by inhibiting the direct reversal pathway of DNA repair, which will prevent formation of the inters ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ben E
Ben is frequently used as a shortened version of the given names Benjamin (name), Benjamin, Benedict (given name), Benedict, Bennett (name), Bennett or Benson (given name), Benson, and is also a given name in its own right. Ben (Hebrew), Ben (in he, בֶּן, ''son of'') forms part of Hebrew surnames, e.g. Abraham ben Abraham ( he, אברהם בן אברהם). Bar (Aramaic)#Aramaic, Bar-, "son of" in Aramaic language, Aramaic, is also seen, e.g. Simon bar Kokhba ( he, שמעון בר כוכבא). Ben meaning "son of" is also found in Arabic as ''Ben'' (dialectal Arabic) or ''bin'' (بن), ''Ibn''/''ebn'' (ابن). People with the given name * Ben Adams (born 1981), member of the British boy band A1 * Ben Affleck (born 1972), American Academy Award-winning actor and screenwriter * Ben Ashkenazy (born 1968/69), American billionaire real estate developer * Ben Askren (born 1984), American sport wrestler and mixed martial artist * Ben Banogu (born 1996), American football player ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mobile, AL
Mobile ( , ) is a city and the county seat of Mobile County, Alabama, United States. The population within the city limits was 187,041 at the 2020 census, down from 195,111 at the 2010 census. It is the fourth-most-populous city in Alabama, after Huntsville, Birmingham, and Montgomery. Alabama's only saltwater port, Mobile is located on the Mobile River at the head of Mobile Bay on the north-central Gulf Coast. The Port of Mobile has always played a key role in the economic health of the city, beginning with the settlement as an important trading center between the French colonists and Native Americans, down to its current role as the 12th-largest port in the United States.Drechsel, Emanuel. ''Mobilian Jargon: Linguistic and Sociohistorical Aspects of a Native American Pidgin''. New York: Oxford University Press, 1997. Mobile is the principal municipality of the Mobile metropolitan area. This region of 430,197 residents is composed Mobile and Washington counties; it ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Academy Of Inventors
The National Academy of Inventors (NAI) is a US non-profit organization dedicated to encouraging inventors in academia, following the model of the National Academies of the United States. It was founded at the University of South Florida in 2010. Starting in 2012, the NAI has inducted 757 Fellows into the organization. Fellows must be named as an inventor on at least one US patent and are selected by the NAI Fellows Committee. The NAI also includes colleges and universities as institutional members, beginning with 9 such institutions in 2012; it now has over 200, including 30 outside the United States.. Since 2013, the National Academy of Inventors and the Intellectual Property Owners Association have released an annual report listing the top 100 universities by the number of US patents. The University of California has topped the list each year. The NAI has held a yearly national conference since 2011. In 2017, US Representative Dennis A. Ross introduced the bill HR 976, w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Alabama At Birmingham
The University of Alabama at Birmingham (UAB) is a Public university#United States, public List of research universities in the United States, research university in Birmingham, Alabama. Developed from an academic extension center established in 1936, the institution became a four-year campus in 1966 and a fully autonomous university in University of Alabama System, the University of Alabama System in 1969. UAB offers 140 programs of study in 12 academic divisions leading to bachelor's degree, bachelor's, master's degree, master's, doctorate, doctoral, and professional degree, professional degrees in the social sciences, social and behavioral sciences, the liberal arts, business, education, engineering, and health-related fields such as medicine, dentistry, optometry, nursing, and public health. In the fall of 2019, 22,080 students from more than 110 countries were enrolled. The UAB Health System, one of the largest academic medical centers in the United States, is affiliated w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and Mathematical Modeling, mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the Biology, biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular biology, molecular and cell biology, cellular studies of individual neurons to neuroimaging, imaging ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oncology
Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is concerned with: * The diagnosis of any cancer in a person (pathology) * Therapy (e.g. surgery, chemotherapy, radiotherapy and other modalities) * Follow-up of cancer patients after successful treatment * Palliative care of patients with terminal malignancies * Ethical questions surrounding cancer care * Screening efforts: ** of populations, or ** of the relatives of patients (in types of cancer that are thought to have a hereditary basis, such as breast cancer) Diagnosis Medical histories remain an important screening tool: the character of the complaints and nonspecific symptoms (such as fatigue, weight loss, unexplained anemia, fever of unknown origin, paraneoplastic phenome ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Consulting
A consultant (from la, consultare "to deliberate") is a professional (also known as ''expert'', ''specialist'', see variations of meaning below) who provides advice and other purposeful activities in an area of specialization. Consulting services generally fall under the domain of professional services, as contingent work. A consultant is employed or involved in giving professional advice to the public or to those practicing the profession. Definition and distinction The Harvard Business School provides a more specific definition of a consultant as someone who advises on "how to modify, proceed in, or streamline a given process within a specialized field". In his book, ''The Consulting Bible'', Alan Weiss defines that "When we onsultantswalk away from a client, the client's conditions should be better than it was before we arrived or we've failed." There is no legal protection given to the job title 'consultant'.Consultancy.ukWhat is a consultant? accessed 29 June 2021 Su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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