Shu Hongbing
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Shu Hongbing
Shu Hongbing (; born January 1967) is a Chinese cytologist and immunologist. He became a member of the Chinese Academy of Sciences in 2011 and TWAS in 2012. Shu is mainly known for his work on cell signal transduction related to immunity. Life Shu Hongbing was born to a poor rural family in Rongchang County, Chongqing. His mother died when he was 9 years old. When Shu entered senior high school, he failed the chemistry exam, and did not know any English. He had to go to school barefoot because he could not afford to buy shoes. However, by the time he finished high school with a national stipend in 1983, he was accepted by Lanzhou University with the highest National Matriculation Examination score in his class. After graduating in 1987, Shu entered the Chinese Academy of Medical Sciences Basic Medical Institute Cell Laboratory, where he obtained his master's degree three years later. In 1990, Shu went to the United States and worked as a research assistant at the University of ...
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Rongchang District
Rongchang District () is a district of Chongqing Municipality, China, bordering Sichuan province to the west. The district, with a population of 800,000, is located in the west of Chongqing. Administration Climate Notable people * Shu Hongbing Shu Hongbing (; born January 1967) is a Chinese cytologist and immunologist. He became a member of the Chinese Academy of Sciences in 2011 and TWAS in 2012. Shu is mainly known for his work on cell signal transduction related to immunity. Life ... (; born 1967) Chinese cytologist and immunologist References External linksRongchang Government website Districts of Chongqing {{Chongqing-geo-stub ...
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TWAS
The World Academy of Sciences (TWAS) is a merit-based science academy established for developing countries, uniting 1,000 scientists in some 70 countries. Its principal aim is to promote scientific capacity and excellence for sustainable development in developing countries. It was formerly known as the ''Third World Academy of Sciences''. Its headquarters is located on the premises of the Abdus Salam International Centre for Theoretical Physics (ICTP) in Trieste, Italy. History TWAS was founded in 1983 under the leadership of the Nobel Laureate Abdus Salam of Pakistan by a group of distinguished scientists who were determined to do something about the dismal state of scientific research in developing countries. * Although developing countries account for 80% of the world's population, only 28% of the world's scientists hail from these countries. This fact reflects the lack of innovative potential necessary to solve real-life problems affecting poor nations. * A chronic lack of ...
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Two-hybrid Screening
Two-hybrid screening (originally known as yeast two-hybrid system or Y2H) is a molecular biology technique used to discover protein–protein interactions (PPIs) and protein–DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively. The premise behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For two-hybrid screening, the transcription factor is split into two separate fragments, called the DNA-binding domain (DBD or often also abbreviated as BD) and activating domain (AD). The BD is the domain responsible for binding to the UAS and the AD is the domain responsible for the activation of transcription. The Y2H is thus a protein-fragment complementation assay. History Pioneered by Stanley Fields and Ok-Kyu Song in 1989, the technique was originally designed to detect protein–protein ...
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