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SeSaM-Biotech GmbH
SeSaM-Biotech GmbH (in short SeSaM-Biotech) is a biotechnology service company founded in 2008 in Bremen and localized in Aachen today. The company has a main focus on Protein Engineering projects based on the QuESt (Quality Enzyme Solutions) strategy and gene library generation using its patented platform technology Sequence Saturation Mutagenesis. Company The SeSaM-Biotech GmbH was founded in 2008 as a spin-off of Jacobs University Bremen Constructor University is an international, private, residential research university located in Vegesack, Bremen, Germany. It offers study programs in engineering, humanities, natural and social sciences, in which students can acquire bachelor' ... by Prof. Ulrich Schwaneberg who had developed and improved the patented key technology Sequence Saturation Mutagenesis (SeSaM) in the preceding years, In 2012, SeSaM-Biotech moved to its new facilities at the Leibniz-Institute for Interactive Materials (DWI) in Aachen. Today, it is a small ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Privately Held Company
A privately held company (or simply a private company) is a company whose shares and related rights or obligations are not offered for public subscription or publicly negotiated in the respective listed markets, but rather the company's stock is offered, owned, traded, exchanged privately, or Over-the-counter (finance), over-the-counter. In the case of a closed corporation, there are a relatively small number of shareholders or company members. Related terms are closely-held corporation, unquoted company, and unlisted company. Though less visible than their public company, publicly traded counterparts, private companies have major importance in the world's economy. In 2008, the 441 list of largest private non-governmental companies by revenue, largest private companies in the United States accounted for ($1.8 trillion) in revenues and employed 6.2 million people, according to ''Forbes''. In 2005, using a substantially smaller pool size (22.7%) for comparison, the 339 companies on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biotechnology
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Contract Research Organization
In the life sciences, a contract research organization (CRO) is a company that provides support to the pharmaceutical, biotechnology, and medical device industries in the form of research services outsourced on a contract basis. A CRO may provide such services as biopharmaceutical development, biological assay development, commercialization, clinical development, clinical trials management, pharmacovigilance, outcomes research, and Real world evidence. CROs are designed to reduce costs for companies developing new medicines and drugs in niche markets. They aim to simplify entry into drug markets, and simplify development, as the need for large pharmaceutical companies to do everything ‘in house’ is now redundant. CROs also support foundations, research institutions, and universities, in addition to governmental organizations (such as the NIH, EMA, etc.). Many CROs specifically provide clinical-study and clinical-trial support for drugs and/or medical devices. However, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aachen
Aachen ( ; ; Aachen dialect: ''Oche'' ; French and traditional English: Aix-la-Chapelle; or ''Aquisgranum''; nl, Aken ; Polish: Akwizgran) is, with around 249,000 inhabitants, the 13th-largest city in North Rhine-Westphalia, and the 28th-largest city of Germany. It is the westernmost city in Germany, and borders Belgium and the Netherlands to the west, the triborder area. It is located between Maastricht (NL) and Liège (BE) in the west, and Bonn and Cologne in the east. The Wurm River flows through the city, and together with Mönchengladbach, Aachen is the only larger German city in the drainage basin of the Meuse. Aachen is the seat of the City Region Aachen (german: link=yes, Städteregion Aachen). Aachen developed from a Roman settlement and (bath complex), subsequently becoming the preferred medieval Imperial residence of Emperor Charlemagne of the Frankish Empire, and, from 936 to 1531, the place where 31 Holy Roman Emperors were crowned Kings of the Germans. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biotechnology
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bremen
Bremen (Low German also: ''Breem'' or ''Bräm''), officially the City Municipality of Bremen (german: Stadtgemeinde Bremen, ), is the capital of the German state Free Hanseatic City of Bremen (''Freie Hansestadt Bremen''), a two-city-state consisting of the cities of Bremen and Bremerhaven. With about 570,000 inhabitants, the Hanseatic city is the 11th largest city of Germany and the second largest city in Northern Germany after Hamburg. Bremen is the largest city on the River Weser, the longest river flowing entirely in Germany, lying some upstream from its mouth into the North Sea, and is surrounded by the state of Lower Saxony. A commercial and industrial city, Bremen is, together with Oldenburg and Bremerhaven, part of the Bremen/Oldenburg Metropolitan Region, with 2.5 million people. Bremen is contiguous with the Lower Saxon towns of Delmenhorst, Stuhr, Achim, Weyhe, Schwanewede and Lilienthal. There is an exclave of Bremen in Bremerhaven, the "Citybremian Overseas Port ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Engineering
Protein engineering is the process of developing useful or valuable proteins. It is a young discipline, with much research taking place into the understanding of protein folding and recognition for protein design principles. It has been used to improve the function of many enzymes for industrial catalysis. It is also a product and services market, with an estimated value of $168 billion by 2017. There are two general strategies for protein engineering: rational protein design and directed evolution. These methods are not mutually exclusive; researchers will often apply both. In the future, more detailed knowledge of protein structure and function, and advances in high-throughput screening, may greatly expand the abilities of protein engineering. Eventually, even unnatural amino acids may be included, via newer methods, such as expanded genetic code, that allow encoding novel amino acids in genetic code. Approaches Rational design In rational protein design, a scientist uses ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sequence Saturation Mutagenesis
Sequence saturation mutagenesis (SeSaM) is a chemo-enzymatic random mutagenesis method applied for the directed evolution of proteins and enzymes. It is one of the most common saturation mutagenesis techniques. In four PCR-based reaction steps, phosphorothioate nucleotides are inserted in the gene sequence, cleaved and the resulting fragments elongated by universal or degenerate nucleotides. These nucleotides are then replaced by standard nucleotides, allowing for a broad distribution of nucleic acid mutations spread over the gene sequence with a preference to transversions and with a unique focus on consecutive point mutations, both difficult to generate by other mutagenesis techniques. The technique was developed by Professor Ulrich Schwaneberg at Jacobs University Bremen and RWTH Aachen University. Technology, development and advantages SeSaM has been developed in order to overcome several of the major limitations encountered when working with standard mutagenesis methods bas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jacobs University Bremen
Constructor University is an international, private, residential research university located in Vegesack, Bremen, Germany. It offers study programs in engineering, humanities, natural and social sciences, in which students can acquire bachelor's, master's or doctorate degrees. Most of the instruction at the university is in English. Constructor University’s students come from more than 110 countries, with about 80% foreign students and approximately 33% international faculty members. History Constructor University (Previously called Jacobs University and International University Bremen) was founded in 1999 with the support of the University of Bremen, Rice University in Houston, Texas, and the Free Hanseatic City of Bremen, with study programs beginning in 2001. The Jacobs Foundation invested €200 million in the institution in November 2006, thus taking over a two-thirds majority of the partnership share. At the beginning of 2007, the university changed its name to Jaco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biotechnology Companies Of Germany
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Contract Research Organizations
In the life sciences, a contract research organization (CRO) is a company that provides support to the pharmaceutical, biotechnology, and medical device industries in the form of research services outsourced on a contract basis. A CRO may provide such services as biopharmaceutical development, biological assay development, commercialization, clinical development, clinical trials management, pharmacovigilance, outcomes research, and Real world evidence. CROs are designed to reduce costs for companies developing new medicines and drugs in niche markets. They aim to simplify entry into drug markets, and simplify development, as the need for large pharmaceutical companies to do everything ‘in house’ is now redundant. CROs also support foundations, research institutions, and universities, in addition to governmental organizations (such as the NIH, EMA, etc.). Many CROs specifically provide clinical-study and clinical-trial support for drugs and/or medical devices. However, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
