Scarlet Fever Serum
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Scarlet Fever Serum
Scarlet fever serum was used beginning in November 1900 after its development in the Sero-Therapeutic Laboratory of Rudolph Hospital in Vienna, Austria. The serum was taken from the blood of horses. Infected children were injected in their abdominal skin by Dr. Paul Moser. Mortality rates from scarlet fever (also known as scarlatina) declined significantly following the use of the blood serum. Moser at first used scarlet fever serum primarily on the most severely sick persons. After achieving positive results it was applied in the first or second day following contraction of scarlet fever. In many cases the children treated demonstrated great improvement in a very short time, with their fevers going away quickly. Moser worked with four hundred children suffering from scarlatina at St. Anne's Hospital. The mortality rate of those he treated was 8.9%. This compared quite favorably when measured against the 13.09% among children in Vienna hospitals where the scarlet fever serum was not ...
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Vienna, Austria
en, Viennese , iso_code = AT-9 , registration_plate = W , postal_code_type = Postal code , postal_code = , timezone = CET , utc_offset = +1 , timezone_DST = CEST , utc_offset_DST = +2 , blank_name = Vehicle registration , blank_info = W , blank1_name = GDP , blank1_info = € 96.5 billion (2020) , blank2_name = GDP per capita , blank2_info = € 50,400 (2020) , blank_name_sec1 = HDI (2019) , blank_info_sec1 = 0.947 · 1st of 9 , blank3_name = Seats in the Federal Council , blank3_info = , blank_name_sec2 = GeoTLD , blank_info_sec2 = .wien , website = , footnotes = , image_blank_emblem = Wien logo.svg , blank_emblem_size = Vienna ( ; german: Wien ; bar ...
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New York-Presbyterian Hospital
The NewYork-Presbyterian Hospital is a nonprofit academic medical center in New York City affiliated with two Ivy League medical schools, Cornell University and Columbia University. The hospital comprises seven distinct campuses located in the New York metropolitan area. The hospital's two flagship medical centers are Columbia University Irving Medical Center and Weill Cornell Medical Center. , the hospital is ranked as the seventh best hospital in the United States and the second in the New York City metropolitan area by '' U.S. News & World Report''. The hospital has more than 6,500 affiliated physicians, 20,000 employees and 2,600 beds in total. It is one of the largest hospitals in the world. NYPH annually treats about 310,000 patients in its emergency department and delivers about 15,000 babies. History NewYork-Presbyterian Hospital was founded in 1771 as New York Hospital by Edinburgh Medical School graduate Samuel Bard. It received a Royal Charter granted by King Geor ...
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Vaccines
A vaccine is a biological preparation that provides active acquired immunity The adaptive immune system, also known as the acquired immune system, is a subsystem of the immune system that is composed of specialized, systemic cells and processes that eliminate pathogens or prevent their growth. The acquired immune system ... to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or Antigen, killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylaxis, prophylact ...
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Streptococcus
''Streptococcus'' is a genus of gram-positive ' (plural ) or spherical bacteria that belongs to the family Streptococcaceae, within the order Lactobacillales (lactic acid bacteria), in the phylum Bacillota. Cell division in streptococci occurs along a single axis, so as they grow, they tend to form pairs or chains that may appear bent or twisted. This differs from staphylococci, which divide along multiple axes, thereby generating irregular, grape-like clusters of cells. Most streptococci are oxidase-negative and catalase-negative, and many are facultative anaerobes (capable of growth both aerobically and anaerobically). The term was coined in 1877 by Viennese surgeon Albert Theodor Billroth (1829–1894), by combining the prefix "strepto-" (from ), together with the suffix "-coccus" (from Modern , from .) In 1984, many bacteria formerly grouped in the genus ''Streptococcus'' were separated out into the genera ''Enterococcus'' and ''Lactococcus''. Currently, over 50 species ...
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Scarlet Fever
Scarlet fever, also known as Scarlatina, is an infectious disease caused by ''Streptococcus pyogenes'' a Group A streptococcus (GAS). The infection is a type of Group A streptococcal infection (Group A strep). It most commonly affects children between five and 15 years of age. The signs and symptoms include a sore throat, fever, headache, swollen lymph nodes, and a characteristic rash. The face is flushed and the rash is red and blanching. It typically feels like sandpaper and the tongue may be red and bumpy. The rash occurs as a result of capillary damage by exotoxins produced by ''S.pyogenes''. On darker pigmented skin the rash may be hard to discern. Scarlet fever affects a small number of people who have strep throat or streptococcal skin infections. The bacteria are usually spread by people coughing or sneezing. It can also be spread when a person touches an object that has the bacteria on it and then touches their mouth or nose. The diagnosis is typically confirmed by ...
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George Frederick Dick
George Frederick Dick (July 21, 1881 – October 10, 1967) was an American physician and bacteriologist best known for his work with scarlet fever. Dick studied scarlet fever whilst serving the Army Medical Corps during World War I. Dick continued with his research into scarlet fever following the war, and in 1923, in collaboration with his wife Gladys Rowena Dick, managed to locate the cause of the disease in a toxin produced by a strain of Streptococcus bacteria. Using this, they were able to create an antitoxin for treatment and a non-toxic vaccine for immunization. In 1933, Dick his wife were awarded the Cameron Prize for Therapeutics of the University of Edinburgh. He was a professor of clinical medicine at Rush Medical College, Chicago (1918–33), and then became the head of the department of medicine at the University of Chicago The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private university, private research university in Chicago, Illin ...
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Gladys Dick
Gladys Rowena Henry Dick (December 18, 1881 – August 21, 1963) was an American physician who co-developed an antitoxin and vaccine for scarlet fever with her husband, George F. Dick. Biography Gladys Rowena Henry was born in Pawnee City, Nebraska in 1881 and earned her B.S. in zoology from the University of Nebraska-Lincoln in 1900. She was a member of the Pi Beta Phi chapter at the University of Nebraska. Because her mother initially objected to Gladys attending medical school, she took graduate classes at Nebraska until 1903, then moved to Baltimore to attend Johns Hopkins University School of Medicine. Graduated in 1907 with her M.D., she then trained for a year at the University of Berlin. Dick's years at Johns Hopkins and Berlin "marked her introduction to biomedical research" and provided opportunities to study experimental cardiac surgery and blood chemistry with Harvey Cushing, W.G. MacCallum, and Milton Winternitz. Dick moved to Chicago in 1911 and contracted scarl ...
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Chicago
(''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = Country , subdivision_name = United States , subdivision_type1 = State , subdivision_type2 = Counties , subdivision_name1 = Illinois , subdivision_name2 = Cook and DuPage , established_title = Settled , established_date = , established_title2 = Incorporated (city) , established_date2 = , founder = Jean Baptiste Point du Sable , government_type = Mayor–council , governing_body = Chicago City Council , leader_title = Mayor , leader_name = Lori Lightfoot ( D) , leader_title1 = City Clerk , leader_name1 = Anna Valencia ( D) , unit_pref = Imperial , area_footnotes = , area_tot ...
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Chronicling America
''Chronicling America'' is an open access, open source newspaper database and companion website. It is produced by the United States National Digital Newspaper Program (NDNP), a partnership between the Library of Congress and the National Endowment for the Humanities. The NDNP was founded in 2005. The ''Chronicling America'' website was publicly launched in March 2007. It is hosted by the Library of Congress. Much of the content hosted on ''Chronicling America'' is in the public domain. The database is searchable by key terms, state, language, time period, or newspaper. The ''Chronicling America'' website contains digitized newspaper pages and information about historic newspapers to place the primary sources in context and support future research. It hosts newspapers written in a variety of languages. In selecting newspapers to digitize, the site relies on the discretion of contributing institutions. The project describes itself as a "long-term effort to develop an Internet-b ...
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Indianapolis Times
The ''Indianapolis Times'' was an evening newspaper that served the city of Indianapolis, Indiana, from 1888 to 1965 when the paper ceased publishing. History The ''Indianapolis Times'' began as the ''Sun'' in 1888, "the only one cent paper in Indiana" at the time. J. J. Sweeney owned the majority of the company and Fred L. Purdy owned a minority share and filled the role of editor. From 1888 to 1899, the ''Sun's'' circulation grew to almost 13,000. The daily paper was renamed the ''Indianapolis Sun'' in 1899. Indiana newspaper businessman Rudolph G. Leeds bought the ''Indianapolis Sun'' in 1910 before selling it to George H. Larke and William D. Boyce in 1913. Under the name ''Evening Sun'' from 1913 to 1914, the circulation of the paper spiked to over 34,000. Boyce and the new co-owner, John W. Banbury, renamed the paper the ''Indiana Daily Times'' in 1914, and it reached a circulation of over 46,000 the following year. It was not until 1922 that the paper became the ''Ind ...
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Rome, Italy
, established_title = Founded , established_date = 753 BC , founder = King Romulus (Romulus and Remus, legendary) , image_map = Map of comune of Rome (metropolitan city of Capital Rome, region Lazio, Italy).svg , map_caption = The territory of the ''comune'' (''Roma Capitale'', in red) inside the Metropolitan City of Rome (''Città Metropolitana di Roma'', in yellow). The white spot in the centre is Vatican City. , pushpin_map = Italy#Europe , pushpin_map_caption = Location within Italy##Location within Europe , pushpin_relief = yes , coordinates = , coor_pinpoint = , subdivision_type = List of sovereign states, Country , subdivision_name = Italy , subdivision_type2 = Regions of Italy, Region , subdivision_name2 = Lazio , subdivision_type3 = Metropolitan cities of Italy, Metropolitan city , subdivision_name3 = Metropolitan City of Rome Capital, Rome Capital , government_footnotes= , ...
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Scarlet Fever
Scarlet fever, also known as Scarlatina, is an infectious disease caused by ''Streptococcus pyogenes'' a Group A streptococcus (GAS). The infection is a type of Group A streptococcal infection (Group A strep). It most commonly affects children between five and 15 years of age. The signs and symptoms include a sore throat, fever, headache, swollen lymph nodes, and a characteristic rash. The face is flushed and the rash is red and blanching. It typically feels like sandpaper and the tongue may be red and bumpy. The rash occurs as a result of capillary damage by exotoxins produced by ''S.pyogenes''. On darker pigmented skin the rash may be hard to discern. Scarlet fever affects a small number of people who have strep throat or streptococcal skin infections. The bacteria are usually spread by people coughing or sneezing. It can also be spread when a person touches an object that has the bacteria on it and then touches their mouth or nose. The diagnosis is typically confirmed by ...
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