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Gladys Rowena Henry Dick (December 18, 1881 – August 21, 1963) was an American physician who co-developed an
antitoxin An antitoxin is an antibody with the ability to neutralize a specific toxin. Antitoxins are produced by certain animals, plants, and bacteria in response to toxin exposure. Although they are most effective in neutralizing toxins, they can also ...
and vaccine for
scarlet fever Scarlet fever, also known as Scarlatina, is an infectious disease caused by ''Streptococcus pyogenes'' a Group A streptococcus (GAS). The infection is a type of Group A streptococcal infection (Group A strep). It most commonly affects childr ...
with her husband, George F. Dick.


Biography

Gladys Rowena Henry was born in
Pawnee City, Nebraska Pawnee City is a city and county seat of Pawnee County, Nebraska, United States. The population was 878 at the 2010 census. History Pawnee City was incorporated in 1858, and is named after the Pawnee Native Americans. By the 1880s, Pawnee Cit ...
in 1881 and earned her B.S. in zoology from the
University of Nebraska-Lincoln A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, t ...
in 1900. She was a member of the
Pi Beta Phi Pi Beta Phi (), often known simply as Pi Phi, is an international women's fraternity founded at Monmouth College, in Monmouth, Illinois on April 28, 1867 as I. C. Sorosis, the first national secret college society of women to be modeled after ...
chapter at the University of Nebraska. Because her mother initially objected to Gladys attending medical school, she took graduate classes at Nebraska until 1903, then moved to Baltimore to attend
Johns Hopkins University School of Medicine The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with the Johns Hopkins Hospi ...
. Graduated in 1907 with her M.D., she then trained for a year at the
University of Berlin Humboldt-Universität zu Berlin (german: Humboldt-Universität zu Berlin, abbreviated HU Berlin) is a German public research university in the central borough of Mitte in Berlin. It was established by Frederick William III on the initiative o ...
. Dick's years at Johns Hopkins and Berlin "marked her introduction to biomedical research" and provided opportunities to study experimental
cardiac surgery Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease (for example, with coronary artery bypass grafting); to corr ...
and blood chemistry with
Harvey Cushing Harvey Williams Cushing (April 8, 1869 – October 7, 1939) was an American neurosurgeon, pathologist, writer, and draftsman. A pioneer of brain surgery, he was the first exclusive neurosurgeon and the first person to describe Cushing's disease. ...
, W.G. MacCallum, and Milton Winternitz. Dick moved to Chicago in 1911 and contracted scarlet fever while working at
Children's Memorial Hospital Ann & Robert H. Lurie Children's Hospital of Chicago, formerly Children's Memorial Hospital and commonly known as Lurie Children's, is a nationally ranked pediatric acute care children's hospital located in Chicago, Illinois. The hospital has 3 ...
. After recovering, she took a research position at the
University of Chicago The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park neighborhood. The University of Chicago is consistently ranked among the b ...
, where she studied kidney pathochemistry with H. Gideon Wells and the etiology of scarlet fever with her future husband, George F. Dick. After they married in 1914, Dick served as a pathologist at Evanston Hospital and later joined her husband at the John R. McCormick Institute for Infectious Diseases. She also served as a bacteriologist for the
United States Public Health Service The United States Public Health Service (USPHS or PHS) is a collection of agencies of the Department of Health and Human Services concerned with public health, containing nine out of the department's twelve operating divisions. The Assistant S ...
and worked at St. Luke's Hospital. In October, 1923, Dick and her husband successfully isolated
hemolytic streptococcus ''Streptococcus pyogenes'' is a species of Gram-positive, aerotolerant bacteria in the genus ''Streptococcus''. These bacteria are extracellular, and made up of non-motile and non-sporing cocci (round cells) that tend to link in chains. They are ...
"as the causative agent of scarlet fever," and later developed the Dick test, a
skin test A skin test is a medical test in which a substance is injected into the skin. Examples * Casoni test * Corneometry * Dick test * Fernandez reaction * Frei test * Hair perforation test * Kveim test * Leishmanin skin test * Lepromin * Patch t ...
which determined a person's susceptibility to the disease and produced "active immunization by larger doses of toxin and antitoxin for treatment, prevention, and diagnosis. They patented their toxin and antitoxin production methods in 1924 and 1926, which produced criticism from the medical field. The Dicks argued that the patents maintained
quality control Quality control (QC) is a process by which entities review the quality of all factors involved in production. ISO 9000 defines quality control as "a part of quality management focused on fulfilling quality requirements". This approach places ...
and ultimately won a lawsuit against the
Lederle Laboratories American Cyanamid Company was a leading American conglomerate which became one of the nation's top 100 manufacturing companies during the 1970s and 1980s, according to the Fortune 500 listings at the time. It started in fertilizer, but added m ...
in 1930 for "patent infringement and improper toxin manufacture." Though the Dicks' antitoxin and vaccine were superseded by penicillin in the 1940s, their work was recognized by a
Charles Mickle Charles Julius Mickle (July 22, 1849 in Stratford, Canada West, now Ontario – November 10, 1919 in Minnedosa, Manitoba) was a politician in Manitoba, Canada. He was a provincial cabinet minister for three years and on two occasions served as t ...
Fellowship Award from the
University of Toronto The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution ...
in 1926 and the Cameron Prize for Therapeutics of the University of Edinburgh, in 1933. Through the 1940s and 1950s, Dick was active in polio research and became an advocate for adoption - founding the Cradle Society in Evanston, IL and serving on its board from 1918 until 1953. She also devised the Dick Aseptic Nursery Technique which provided "strict sterilization and aseptic procedures" to prevent cross infection among infants. Dick died of
stroke A stroke is a medical condition in which poor blood flow to the brain causes cell death. There are two main types of stroke: ischemic, due to lack of blood flow, and hemorrhagic, due to bleeding. Both cause parts of the brain to stop functionin ...
in
Palo Alto, California Palo Alto (; Spanish language, Spanish for "tall stick") is a charter city in the northwestern corner of Santa Clara County, California, United States, in the San Francisco Bay Area, named after a Sequoia sempervirens, coastal redwood tree kno ...
on August 21, 1963.


References


Further reading

* {{DEFAULTSORT:Dick, Gladys 1881 births 1963 deaths Scarlet fever University of Nebraska–Lincoln alumni American bacteriologists Women microbiologists Johns Hopkins University alumni People from Pawnee City, Nebraska 20th-century American women scientists 20th-century American scientists