Samer Hattar
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Samer Hattar
Samer Hattar ( ar, سامر حتر) is a chronobiologist and a leader in the field of non-image forming photoreception. He is the Chief of the Section on Light and Circadian Rhythms at the National Institute of Mental Health, part of the National Institutes of Health. He was previously an associate professor in the Department of Neuroscience and the Department of Biology at Johns Hopkins University in Baltimore, MD. He is best known for his investigation into the role of melanopsin and intrinsically photosensitive retinal ganglion cells (ipRGC) in the entrainment of circadian rhythms. Life Samer Hattar was born in Amman, Jordan to a Jordanian father and a Lebanese mother. Raised in a Christian family, he planned on becoming a priest. He studied at Terra Sancta High School, a Catholic high school in Amman, from 1978 to 1988. He earned good grades in his classes and fell in love with biology when introduced to Mendel's pea plant experiments. This passion inspired him to pursue a ...
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Amman, Jordan
Amman (; ar, عَمَّان, ' ; Ammonite: 𐤓𐤁𐤕 𐤏𐤌𐤍 ''Rabat ʻAmān'') is the capital and largest city of Jordan, and the country's economic, political, and cultural center. With a population of 4,061,150 as of 2021, Amman is Jordan's primate city and is the largest city in the Levant region, the fifth-largest city in the Arab world, and the ninth largest metropolitan area in the Middle East. The earliest evidence of settlement in Amman dates to the 8th millennium BC, in a Neolithic site known as 'Ain Ghazal, where the world's oldest statues of the human form have been unearthed. During the Iron Age, the city was known as Rabat Aman and served as the capital of the Ammonite Kingdom. In the 3rd century BC, Ptolemy II Philadelphus, Pharaoh of Ptolemaic Egypt, rebuilt the city and renamed it "Philadelphia", making it a regional center of Hellenistic culture. Under Roman rule, Philadelphia was one of the ten Greco-Roman cities of the Decapolis before being di ...
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Intrinsically Photosensitive Retinal Ganglion Cells
Intrinsically photosensitive retinal ganglion cells (ipRGCs), also called photosensitive retinal ganglion cells (pRGC), or melanopsin-containing retinal ganglion cells (mRGCs), are a type of neuron in the retina of the mammalian eye. The presence of (something like) ipRGCs was first suspected in 1927 when rodless, coneless mice still responded to a light stimulus through pupil constriction, This implied that rods and cones are not the only light-sensitive neurons in the retina. Yet research on these cells did not advance until the 1980s. Recent research has shown that these retinal ganglion cells, unlike other retinal ganglion cells, are intrinsically photosensitive due to the presence of melanopsin, a light-sensitive protein. Therefore they constitute a third class of photoreceptors, in addition to rod and cone cells. Overview Compared to the rods and cones, the ipRGCs respond more sluggishly and signal the presence of light over the long term. They represent a very small ...
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Johns Hopkins University School Of Medicine
The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with the Johns Hopkins Hospital and Johns Hopkins Children's Center, established in 1889. It has consistently ranked among the top medical schools in the United States in terms of the number/amount of research grants/funding awarded by the National Institutes of Health, among other measures. History The founding physicians (the "Four Doctors") of the Johns Hopkins School of Medicine included pathologist William Henry Welch (1850–1934), the first dean of the school and a mentor to generations of research scientists; a Canadian, internist Sir William Osler (1849–1919), regarded as the ''Father of Modern Medicine'', having been perhaps the most influential physician of the late 19th and early 20th centuries as author of '' The Principles and Practice of Medicine'' ...
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Aplysia
''Aplysia'' () is a genus of medium-sized to extremely large sea slugs, specifically sea hares, which are one clade of large sea slugs, marine gastropod mollusks. These benthic herbivorous creatures can become rather large compared with most other mollusks. They graze in tidal and subtidal zones of tropical waters, mostly in the Indo-Pacific Ocean (23 species); but they can also be found in the Atlantic Ocean (12 species), with a few species occurring in the Mediterranean. ''Aplysia'' species, when threatened, frequently release clouds of ink, it is believed in order to blind the attacker (though they are in fact considered edible by relatively few species). Following the lead of Eric R. Kandel, the genus has been studied as a model organism by neurobiologists, because its gill and siphon withdrawal reflex, as studied in ''Aplysia californica'', is mediated by electrical synapses, which allow several neurons to fire synchronously. This quick neural response is necessary f ...
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Transcription Factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. The function of TFs is to regulate—turn on and off—genes in order to make sure that they are expressed in the desired cells at the right time and in the right amount throughout the life of the cell and the organism. Groups of TFs function in a coordinated fashion to direct cell division, cell growth, and cell death throughout life; cell migration and organization (body plan) during embryonic development; and intermittently in response to signals from outside the cell, such as a hormone. There are up to 1600 TFs in the human genome. Transcription factors are members of the proteome as well as regulome. TFs work alone or with other proteins in a complex, by promoting (as an activator), or blocking (as a repressor) the recruitment of RNA ...
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Beirut
Beirut, french: Beyrouth is the capital and largest city of Lebanon. , Greater Beirut has a population of 2.5 million, which makes it the third-largest city in the Levant region. The city is situated on a peninsula at the midpoint of Lebanon's Mediterranean coast. Beirut has been inhabited for more than 5,000 years, and was one of Phoenicia's most prominent city states, making it one of the oldest cities in the world (see Berytus). The first historical mention of Beirut is found in the Amarna letters from the New Kingdom of Egypt, which date to the 14th century BC. Beirut is Lebanon's seat of government and plays a central role in the Lebanese economy, with many banks and corporations based in the city. Beirut is an important seaport for the country and region, and rated a Beta + World City by the Globalization and World Cities Research Network. Beirut was severely damaged by the Lebanese Civil War, the 2006 Lebanon War, and the 2020 massive explosion in the ...
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Prince Hassan Bin Al-Talal
Prince Hassan bin Talal ( ar, الحسن بن طلال, born 20 March 1947) is a member of the Jordanian royal family who was previously Crown Prince from 1965 to 1999, being removed just three weeks before King Hussein's death. Family Prince Hassan is the third son of King Talal and Queen Zein, brother of King Hussein and uncle of King Abdullah II. In 1968, Prince El Hassan married Sarvath Ikramullah, daughter of Pakistani politician and diplomat Mohammed Ikramullah, and female Pakistani-Bengali politician, diplomat and Urdu author, Begum Shaista Suhrawardy Ikramullah. They first met in London in 1958, when they were both youngsters, and have four children together: * Princess Rahma (born 13 August 1969) * Princess Sumaya (born 14 May 1971) * Princess Badiya (born 28 March 1974) * Prince Rashid (born 20 May 1979) Education Prince Hassan was educated first in Amman. He then attended Sandroyd School in Wiltshire before going on to Summer Fields School, Oxford, followed by ...
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Irbid
Irbid ( ar, إِربِد), known in ancient times as Arabella or Arbela (Άρβηλα in Ancient Greek language, Ancient Greek), is the capital and largest city of the Irbid Governorate. It also has the second largest metropolitan population in Jordan after Amman, with a population of around 2,003,800. Irbid is located about north of Amman on the northern ridge of the Gilead, equidistant from Pella, Jordan, Pella, Beit Ras (Capitolias), and Um Qais, and approximately south of the Syrian border. Irbid was built on successive Early Bronze Age settlements and was possibly the Hebrew Bible, biblical Beth Arbel and the Arbila of the Decapolis, a Hellenistic league of the 1st century BCE through the 2nd century CE. The population of Irbid swelled in the late 19th century, and prior to 1948 it served as a significant centre of transit trade. Irbid is the second largest metropolitan in Jordan by population after Amman. But as a city Irbid is the third largest one after Amman and Zarqa ...
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Gregor Mendel
Gregor Johann Mendel, Augustinians, OSA (; cs, Řehoř Jan Mendel; 20 July 1822 – 6 January 1884) was a biologist, meteorologist, mathematician, Augustinians, Augustinian friar and abbot of St Thomas's Abbey, Brno, St. Thomas' Abbey in Brünn (''Brno''), Margraviate of Moravia. Mendel was born in a Sudeten Germans, German-speaking family in the Austrian Silesia, Silesian part of the Austrian Empire (today's Czech Republic) and gained posthumous recognition as the founder of the modern science of genetics. Though farmers had known for millennia that crossbreeding of animals and plants could favor certain desirable trait (biological), traits, Mendel's pea plant experiments conducted between 1856 and 1863 established many of the rules of biological inheritance, heredity, now referred to as the laws of Mendelian inheritance. Mendel worked with seven characteristics of pea plants: plant height, pod shape and color, seed shape and color, and flower position and color. Taking seed ...
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Priest
A priest is a religious leader authorized to perform the sacred rituals of a religion, especially as a mediatory agent between humans and one or more deities. They also have the authority or power to administer religious rites; in particular, rites of sacrifice to, and propitiation of, a deity or deities. Their office or position is the 'priesthood', a term which also may apply to such persons collectively. A priest may have the duty to hear confessions periodically, give marriage counseling, provide prenuptial counseling, give spiritual direction, teach catechism, or visit those confined indoors, such as the sick in hospitals and nursing homes. Description According to the trifunctional hypothesis of prehistoric Proto-Indo-European society, priests have existed since the earliest of times and in the simplest societies, most likely as a result of agricultural surplus and consequent social stratification. The necessity to read sacred texts and keep temple or church rec ...
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Christians
Christians () are people who follow or adhere to Christianity, a monotheistic Abrahamic religion based on the life and teachings of Jesus Christ. The words ''Christ'' and ''Christian'' derive from the Koine Greek title ''Christós'' (Χριστός), a translation of the Biblical Hebrew term ''mashiach'' (מָשִׁיחַ) (usually rendered as ''messiah'' in English). While there are diverse interpretations of Christianity which sometimes conflict, they are united in believing that Jesus has a unique significance. The term ''Christian'' used as an adjective is descriptive of anything associated with Christianity or Christian churches, or in a proverbial sense "all that is noble, and good, and Christ-like." It does not have a meaning of 'of Christ' or 'related or pertaining to Christ'. According to a 2011 Pew Research Center survey, there were 2.2 billion Christians around the world in 2010, up from about 600 million in 1910. Today, about 37% of all Christians live in the Am ...
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Jordan
Jordan ( ar, الأردن; tr. ' ), officially the Hashemite Kingdom of Jordan,; tr. ' is a country in Western Asia. It is situated at the crossroads of Asia, Africa, and Europe, within the Levant region, on the East Bank of the Jordan River. Jordan is bordered by Saudi Arabia to the south and east, Iraq to the northeast, Syria to the north, and the Palestinian West Bank, Israel, and the Dead Sea to the west. It has a coastline in its southwest on the Gulf of Aqaba's Red Sea, which separates Jordan from Egypt. Amman is Jordan's capital and largest city, as well as its economic, political, and cultural centre. Modern-day Jordan has been inhabited by humans since the Paleolithic period. Three stable kingdoms emerged there at the end of the Bronze Age: Ammon, Moab and Edom. In the third century BC, the Arab Nabataeans established their Kingdom with Petra as the capital. Later rulers of the Transjordan region include the Assyrian, Babylonian, Roman, Byzantine, Rashidun ...
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