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STX5
Syntaxin-5 is a protein that in humans is encoded by the ''STX5'' gene. Interactions STX5 has been shown to interact with: * BET1L, * GOSR1, * GOSR2, * NAPA, and * USO1 General vesicular transport factor p115 is a protein that in humans is encoded by the ''USO1'' gene. Function The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during i .... References Further reading * * * * * * * * * * * * * * * {{gene-11-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BET1L
BET1-like protein is a protein that in humans is encoded by the ''BET1L'' gene. Interactions BET1L has been shown to Protein-protein interaction, interact with: * GOSR1, * STX5, and * YKT6. References External links * Further reading * * * * * * * * * * * * {{gene-11-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GOSR1
Golgi SNAP receptor complex member 1 is a protein that in humans is encoded by the ''GOSR1'' gene. This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi apparatus and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Interactions GOSR1 has been shown to interact with USO1, BET1L and STX5 Syntaxin-5 is a protein that in humans is encoded by the ''STX5'' gene. Interactions STX5 has been shown to interact with: * BET1L, * GOSR1, * GOSR2, * NAPA, and * USO1 General vesicular transport factor p115 is a protein that in hu .... References Further reading * * * * * * * * * * * * {{gene-17-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GOSR2
Golgi SNAP receptor complex member 2 is a protein that in humans is encoded by the ''GOSR2'' gene. Function This gene encodes a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Due to its chromosomal location and trafficking function, this gene may be involved in familial essential hypertension. Three transcript variants encoding three different isoforms have been found for this gene. Mutations in the ''GOSR2'' gene are linked with North Sea progressive myoclonus epilepsy (NS-PME), a rare subtype of progressive myoclonus epilepsy that is prevalent in northern Europe. Interactions GOSR2 has been shown to interact with USO1 and STX5 Syntaxin-5 is a protein that in humans is encoded by the ''STX5'' gene. Interactions STX5 has been shown to interact with: * BET1L, * GOSR1, * GOSR2, * NAPA, and * USO1 General vesicular transport factor p115 is a protein that in hu .... References Further reading ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NAPA (gene)
N-ethylmaleimide-sensitive factor Attachment Protein Alpha, also known as SNAP-α, is a SNAP protein that is involved in the intra-cellular trafficking and fusing of vesicles to target membranes in cells. Function The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
