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STKE
''Science Signaling'' is a peer-reviewed scientific journal that is focused on cell signaling and regulation. It is published weekly by the American Association for the Advancement of Science (AAAS). The editor-in-chief (Chief Scientific Editor) is Michael B. Yaffe (Massachusetts Institute of Technology), and the journal is part of thScience Family of Journalsof which Holden Thorp is the Editor-in-Chief. Scope The journal covers research on cell signaling and the processes of cellular regulation. In addition, the journal covers signaling networks, synthetic biology, systems biology, drug discovery, and computation and modeling of regulatory pathways. Besides full length articles, it also publishes reviews, perspectives, meeting reports, presentations (for a wider audience), protocols, book reviews, teaching resources, a glossary, and a Journal Club section. History The journal was established in 1999 as ''Science's STKE''. On January 8, 2008, it obtained its current nam ...
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Signal Transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response. Proteins responsible for detecting stimuli are generally termed receptors, although in some cases the term sensor is used. The changes elicited by ligand binding (or signal sensing) in a receptor give rise to a biochemical cascade, which is a chain of biochemical events known as a signaling pathway. When signaling pathways interact with one another they form networks, which allow cellular responses to be coordinated, often by combinatorial signaling events. At the molecular level, such responses include changes in the transcription or translation of genes, and post-translational and conformational changes in proteins, as well as changes in their location. These molecular events are the basic mechanisms controlling cell gro ...
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American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal ...
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Science Signaling Journal Cover
Science is a systematic endeavor that builds and organizes knowledge in the form of testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence for scientific reasoning is tens of thousands of years old. The earliest written records in the history of science come from Ancient Egypt and Mesopotamia in around 3000 to 1200 BCE. Their contributions to mathematics, astronomy, and medicine entered and shaped Greek natural philosophy of classical antiquity, whereby formal attempts were made to provide explanations of events in the physical world based on natural causes. After the fall of the Western Roman Empire, knowledge of Greek conceptions of the world deteriorated in Western Europe during the early centuries (400 to 1000 CE) of the Middle Ages, but was preserved in the Muslim world during the Islamic Golden Age and later by the efforts of Byzantine Greek scholars who brought Greek ...
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Publications Established In 1999
To publish is to make content available to the general public.Berne Convention, article 3(3)
URL last accessed 2010-05-10.
Universal Copyright Convention, Geneva text (1952), article VI
. URL last accessed 2010-05-10.
While specific use of the term may vary among countries, it is usually applied to text, images, or other content, including paper (

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Molecular And Cellular Biology Journals
A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and biochemistry, the distinction from ions is dropped and ''molecule'' is often used when referring to polyatomic ions. A molecule may be homonuclear, that is, it consists of atoms of one chemical element, e.g. two atoms in the oxygen molecule (O2); or it may be heteronuclear, a chemical compound composed of more than one element, e.g. water (two hydrogen atoms and one oxygen atom; H2O). In the kinetic theory of gases, the term ''molecule'' is often used for any gaseous particle regardless of its composition. This relaxes the requirement that a molecule contains two or more atoms, since the noble gases are individual atoms. Atoms and complexes connected by non-covalent interactions, such as hydrogen bonds or ionic bonds, are typically not consi ...
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Thomson Reuters
Thomson Reuters Corporation ( ) is a Canadian multinational media conglomerate. The company was founded in Toronto, Ontario, Canada, where it is headquartered at the Bay Adelaide Centre. Thomson Reuters was created by the Thomson Corporation's purchase of the British company Reuters Group in April 2008. It is majority-owned by The Woodbridge Company, a holding company for the Thomson family. History Thomson Corporation The forerunner of the Thomson company was founded by Roy Thomson in 1934 in Ontario, as the publisher of ''The Timmins Daily Press''. In 1953, Thomson acquired the '' Scotsman'' newspaper and moved to Scotland the following year. He consolidated his media position in Scotland in 1957, when he won the franchise for Scottish Television. In 1959, he bought the Kemsley Group, a purchase that eventually gave him control of the '' Sunday Times''. He separately acquired the ''Times'' in 1967. He moved into the airline business in 1965, when he acquired Brit ...
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Impact Factor
The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as indexed by Clarivate's Web of Science. As a journal-level metric, it is frequently used as a proxy for the relative importance of a journal within its field; journals with higher impact factor values are given the status of being more important, or carry more prestige in their respective fields, than those with lower values. While frequently used by universities and funding bodies to decide on promotion and research proposals, it has come under attack for distorting good scientific practices. History The impact factor was devised by Eugene Garfield, the founder of the Institute for Scientific Information (ISI) in Philadelphia. Impact factors began to be calculated yearly starting from 1975 for journals listed in the '' Journal Citation ...
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Journal Citation Reports
''Journal Citation Reports'' (''JCR'') is an annual publicationby Clarivate Analytics (previously the intellectual property of Thomson Reuters). It has been integrated with the Web of Science and is accessed from the Web of Science-Core Collections. It provides information about academic journals in the natural sciences and social sciences, including impact factors. The ''JCR'' was originally published as a part of '' Science Citation Index''. Currently, the ''JCR'', as a distinct service, is based on citations compiled from the '' Science Citation Index Expanded'' and the '' Social Sciences Citation Index''.- - - Basic journal information The information given for each journal includes: * the basic bibliographic information of publisher, title abbreviation, language, ISSN * the subject categories (there are 171 such categories in the sciences and 54 in the social sciences) Citation information * Basic citation data: ** the number of articles published during that year and ...
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Scopus
Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences. It covers three types of sources: book series, journals, and trade journals. All journals covered in the Scopus database are reviewed for sufficiently high quality each year according to four types of numerical quality measure for each title; those are ''h''-Index, CiteScore, SJR ( SCImago Journal Rank) and SNIP ( Source Normalized Impact per Paper). Searches in Scopus also incorporate searches of patent databases. Overview Comparing ease of use and coverage of Scopus and the Web of Science (WOS), a 2006 study concluded that "Scopus is easy to navigate, even for the novice user. ... The ability to search both forward and backward from a part ...
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EMCare
EmCare Holdings Inc., or EmCare, was an American provider of physician practice management services for emergency departments, inpatient physician services or hospitals, acute care surgery, trauma and general surgery, women's and children's services, radiology / teleradiology programs and anesthesiology services. Founded in 1972, EmCare had more than 1,000 contracts with client hospitals in 42 states. Laidlaw acquired EmCare in 1997. In 2004, Laidlaw sold EmCare and American Medical Response to Onex. Onex formed Emergency Medical Services Corporation as the parent of its two acquisitions. EMSC went public in December of that year. In 2011, EMSC was acquired by Clayton, Dubilier & Rice. On June 11, 2013, EMSC changed names to Envision Healthcare and went public as EVHC. AMR and Evolution Health also are a part of Envision Healthcare. The company had been criticized for encouraging the practice of "out-of-network billing", which causes patients to be billed directly and at a muc ...
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EMBiology
EMBiology is a bibliographic database established in June 2005, and produced by Elsevier. ''EMBiology'' focuses on indexing the literature in the life sciences in general. Coverage includes science in the laboratory ( fundamental research) and science in the field ( applied research). It is designed to be smaller than EMBASE, with abstracting and indexing for 1,800 journals not covered by the larger database. However, there is some overlap. Hence, ''EMBiology'' is specifically designed for academic institutions that range from small to mid-size and all biotechnology and pharmaceutical companies. Global in scope, and with back file coverage to 1980, this database contains over four million bibliographic records, with an additional 250,000 records added annually. ''EMBiology''has cover to cover indexing of 2,800 active titles; these are peer reviewed journals, trade publications, and journals that are only in electronic format. A life science thesaurus known as ''EMTREE'' (see se ...
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