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SCIEX
SCIEX is a manufacturer of mass spectrometry instrumentation used in biomedical and environmental applications. Originally started by scientists from the University of Toronto Institute for Aerospace Studies, it is now part of Danaher Corporation with the SCIEX R&D division still located in Toronto, Canada. History SCIEX was founded in 1974 by Canadian scientists Barry French, a professor at the University of Toronto Institute for Aerospace Studies (UTIAS), Neil Reid, Adele Buckley, and businessman William Breukelman, to develop a mass spectrometer system based on atmospheric pressure ionisation and direct air sampling. Breukelman is also co-founder and former CEO of IMAX Corporation. In 1981 SCIEX was acquired by MDS Inc., a Canadian medical services and equipment company. A joint venture was formed with PerkinElmer for sales and marketing of the inductively coupled plasma mass spectrometry (ICPMS) product line. In 1986, the joint venture was extended to include the liquid c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barry French (scientist)
(John) Barry French, born August 22, 1931, is a Canadian scientist and entrepreneur. He received his PhD in Chemical Engineering from the University of Toronto in 1961. He is a Fellow of the Royal Society of Canada and a Fellow of the Canadian Academy of Engineering. French was appointed a Member of the Order of Canada in 2007 and is co-founder of SCIEX, a mass spectrometer company now owned by Danaher Corporation. Research Barry French became full professor at the University of Toronto Institute of Aerospace Studies (UTIAS) in 1968, and served as Associate Director from 1974 - 1982. He was half-time Dean of the University of Toronto School of Graduate Studies from 1982-1985. French's early research interests were in the field of molecular beams, rarefied gas dynamics and space simulation. He developed a hypersonic beam space simulator at UTIAS. In 1969 he was asked by NASA to collaborate with Alfred O. C. Nier at the University of Minnesota by making his apparatus avail ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Danaher Corporation
Danaher Corporation is an American globally diversified conglomerate with its headquarters in Washington, D.C. The company designs, manufactures, and markets professional, medical, industrial, and commercial products and services. The company's 3 platforms are " Life Sciences", "Diagnostics", and "Environmental & Applied Solutions". Danaher is ranked 130th on the Fortune 500 2021. The company is named after Danaher Creek in Western Montana. Founders Steven M. Rales and Mitchell Rales first conceptualized the company while fishing there. Danaher was one of the first companies in North America to adopt " Kaizen" principles to manufacturing, which is a lean manufacturing Japanese philosophy of continuous improvement, and elimination of waste. History The company was organized in 1969 as a Massachusetts real estate investment trust under its former name DMG, Inc. In 1978, DMG, Inc. was reorganized as a Florida corporation and changed its name to Diversified Mortgage Investors, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atmospheric-pressure Chemical Ionization
Atmospheric pressure chemical ionization (APCI) is an ionization method used in mass spectrometry which utilizes gas-phase ion-molecule reactions at atmospheric pressure (105 Pa), commonly coupled with high-performance liquid chromatography (HPLC). APCI is a soft ionization method similar to chemical ionization where primary ions are produced on a solvent spray. The main usage of APCI is for polar and relatively less polar thermally stable compounds with molecular weight less than 1500 Da. The application of APCI with HPLC has gained a large popularity in trace analysis detection such as steroids, pesticides and also in pharmacology for drug metabolites. Instrument structure A typical APCI source usually consists of three main parts: a sample inlet, a corona discharge needle, and an ion transfer region under intermediate pressure. In the case of the heated nebulizer inlet from an LC, as shown in the figure, the eluate flows at 0.2 to 2.0 mL/min into a pneumatic nebulizer which c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Breukelman
William Breukelman, O.C., MBA, P.ENG, is the former principal and Chairman of IMAX Corporation, and co-founder (with Barry French) and former CEO and Chairman of SCIEX SCIEX is a manufacturer of mass spectrometry instrumentation used in biomedical and environmental applications. Originally started by scientists from the University of Toronto Institute for Aerospace Studies, it is now part of Danaher Corporatio ..., whose technology the Office of the Governor General of Canada has described as "breakthrough", and Business Arts Inc., which funds startups. He was appointed an Officer of the Order of Canada in 2013. Awards and honors *Engineering Alumni Hall of Distinction Award: 2015, University of Toronto References Canadian chief executives University of Toronto alumni Canadian chemical engineers Living people Year of birth missing (living people) Officers of the Order of Canada {{Canada-business-bio-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Liquid Chromatography–mass Spectrometry
Liquid chromatography–mass spectrometry (LC–MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides spectral information that may help to identify (or confirm the suspected identity of) each separated component. MS is not only sensitive, but provides selective detection, relieving the need for complete chromatographic separation. LC-MS is also appropriate for metabolomics because of its good coverage of a wide range of chemicals. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin. There ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bp Spill
The ''Deepwater Horizon'' oil spill (also referred to as the "BP oil spill") was an industrial disaster that began on 20 April 2010 off of the coast of the United States in the Gulf of Mexico on the BP-operated Macondo Prospect, considered to be the largest marine oil spill in the history of the petroleum industry and estimated to be 8 to 31 percent larger in volume than the previous largest, the Ixtoc I oil spill, also in the Gulf of Mexico. The United States federal government estimated the total discharge at . After several failed efforts to contain the flow, the well was declared sealed on 19 September 2010. Reports in early 2012 indicated that the well site was still leaking. The ''Deepwater Horizon'' oil spill is regarded as one of the largest environmental disasters in world history. A massive response ensued to protect beaches, wetlands and estuaries from the spreading oil utilizing skimmer ships, floating booms, controlled burns and of oil dispersant. Due ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Technology Companies Of Canada
Technology is the application of knowledge to reach practical goals in a specifiable and reproducible way. The word ''technology'' may also mean the product of such an endeavor. The use of technology is widely prevalent in medicine, science, industry, communication, transportation, and daily life. Technologies include physical objects like utensils or machines and intangible tools such as software. Many technological advancements have led to societal changes. The earliest known technology is the stone tool, used in the prehistoric era, followed by fire use, which contributed to the growth of the human brain and the development of language in the Ice Age. The invention of the wheel in the Bronze Age enabled wider travel and the creation of more complex machines. Recent technological developments, including the printing press, the telephone, and the Internet have lowered communication barriers and ushered in the knowledge economy. While technology contributes to economic de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quadrupole Mass Analyzer
The quadrupole mass analyzer, originally conceived by Nobel Laureate Wolfgang Paul and his student Helmut Steinwedel, also known as quadrupole mass filter, is one type of mass analyzer used in mass spectrometry. As the name implies, it consists of four cylindrical rods, set parallel to each other. In a quadrupole mass spectrometer (QMS) the quadrupole is the ''mass analyzer'' - the component of the instrument responsible for selecting sample ions based on their mass-to-charge ratio (''m/z''). Ions are separated in a quadrupole based on the stability of their trajectories in the oscillating electric fields that are applied to the rods. Principle of operation The quadrupole consists of four parallel metal rods. Each opposing rod pair is connected together electrically, and a radio frequency (RF) voltage with a DC offset voltage is applied between one pair of rods and the other. Ions travel down the quadrupole between the rods. Only ions of a certain mass-to-charge ratio will reach t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Research Council Canada
The National Research Council Canada (NRC; french: Conseil national de recherches Canada) is the primary national agency of the Government of Canada dedicated to science and technology research & development. It is the largest federal research & development organization in Canada. The Minister of Innovation, Science, and Economic Development (currently, François-Philippe Champagne) is responsible for the NRC. Mandate NRC is an agency of the Government of Canada, and its mandate is set out in the '' National Research Council Act''. Under the Act, the NRC is responsible for: * Undertaking, assisting or promoting scientific and industrial research in fields of importance to Canada; * Providing vital scientific and technological services to the research and industrial communities; * Investigating standards and methods of measurement; * Working on the standardization and certification of scientific and technical apparatus, instruments and materials used or usable by Canadian in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cornell University
Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach and make contributions in all fields of knowledge—from the classics to the sciences, and from the theoretical to the applied. These ideals, unconventional for the time, are captured in Cornell's founding principle, a popular 1868 quotation from founder Ezra Cornell: "I would found an institution where any person can find instruction in any study." Cornell is ranked among the top global universities. The university is organized into seven undergraduate colleges and seven graduate divisions at its main Ithaca campus, with each college and division defining its specific admission standards and academic programs in near autonomy. The university also administers three satellite campuses, two in New York City and one in Education City, Qatar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Aerospace
British Aerospace plc (BAe) was a British aircraft, munitions and defence-systems manufacturer. Its head office was at Warwick House in the Farnborough Aerospace Centre in Farnborough, Hampshire. Formed in 1977, in 1999 it purchased Marconi Electronic Systems, the defence electronics and naval shipbuilding subsidiary of the General Electric Company plc, to form BAE Systems. History Formation and privatisation The company has its origins in the Aircraft and Shipbuilding Industries Act 1977, which called for the nationalisation and merger of the British Aircraft Corporation, Hawker Siddeley Aviation, Hawker Siddeley Dynamics and Scottish Aviation. On 29 April 1977, the new entity was formed in the United Kingdom as a statutory corporation. Under the provisions of the ''British Aerospace Act 1980'' on 1 January the statutory corporation was transferred to a limited company, which then re-registered as a public limited company (plc), under the name "British Aerospace Public Li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inductively Coupled Plasma Mass Spectrometry
Inductively coupled plasma mass spectrometry (ICP-MS) is a type of mass spectrometry that uses an inductively coupled plasma to ionize the sample. It atomizes the sample and creates atomic and small polyatomic ions, which are then detected. It is known and used for its ability to detect metals and several non-metals in liquid samples at very low concentrations. It can detect different isotopes of the same element, which makes it a versatile tool in isotopic labeling. Compared to atomic absorption spectroscopy, ICP-MS has greater speed, precision, and sensitivity. However, compared with other types of mass spectrometry, such as thermal ionization mass spectrometry (TIMS) and glow discharge mass spectrometry (GD-MS), ICP-MS introduces many interfering species: argon from the plasma, component gases of air that leak through the cone orifices, and contamination from glassware and the cones. Components Inductively coupled plasma An inductively coupled plasma is a plasma that is ener ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
