SARS-CoV-2 Eta Variant
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SARS-CoV-2 Eta Variant
The Eta variant is a variant of SARS-CoV-2, the virus that causes COVID-19. The Eta variant or lineage B.1.525, also called VUI-21FEB-03 (previously VUI-202102/03) by Public Health England (PHE) and formerly known as UK1188, 21D or 20A/S:484K, does not carry the same N501Y mutation found in Alpha, Beta and Gamma, but carries the same E484K-mutation as found in the Gamma, Zeta, and Beta variants, and also carries the same ΔH69/ΔV70 deletion (a deletion of the amino acids histidine and valine in positions 69 and 70) as found in Alpha, N439K variant (B.1.141 and B.1.258) and Y453F variant (Cluster 5). Eta differs from all other variants by having both the E484K-mutation and a new F888L mutation (a substitution of phenylalanine (F) with leucine (L) in the S2 domain of the spike protein). As of 5 March 2021, it had been detected in 23 countries. It has also been reported in Mayotte, the overseas department/region of France. The first cases were detected in December 2020 in the UK ...
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Eta Variant Countries
Eta (uppercase , lowercase ; grc, ἦτα ''ē̂ta'' or ell, ήτα ''ita'' ) is the seventh letter of the Greek alphabet, representing the close front unrounded vowel . Originally denoting the voiceless glottal fricative in most dialects, its sound value in the classical Attic dialect of Ancient Greek was a long open-mid front unrounded vowel , raised to in hellenistic Greek, a process known as iotacism or itacism. In the ancient Attic number system (Herodianic or acrophonic numbers), the number 100 was represented by "", because it was the initial of , the ancient spelling of = "one hundred". In the later system of (Classical) Greek numerals eta represents 8. Eta was derived from the Phoenician letter heth . Letters that arose from eta include the Latin H and the Cyrillic letter И and Й. History Consonant h The letter shape 'H' was originally used in most Greek dialects to represent the voiceless glottal fricative . In this function, it was borrowed in the ...
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France
France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pacific and Indian Oceans. Its Metropolitan France, metropolitan area extends from the Rhine to the Atlantic Ocean and from the Mediterranean Sea to the English Channel and the North Sea; overseas territories include French Guiana in South America, Saint Pierre and Miquelon in the North Atlantic, the French West Indies, and many islands in Oceania and the Indian Ocean. Due to its several coastal territories, France has the largest exclusive economic zone in the world. France borders Belgium, Luxembourg, Germany, Switzerland, Monaco, Italy, Andorra, and Spain in continental Europe, as well as the Kingdom of the Netherlands, Netherlands, Suriname, and Brazil in the Americas via its overseas territories in French Guiana and Saint Martin (island), ...
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SARS-CoV-2 Lambda Variant
Lambda variant, also known as lineage C.37, is a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in Peru in August 2020. On 14 June 2021, the World Health Organization (WHO) named it Lambda variant and designated it as a variant of interest. Updated frequently. It has spread to at least 30 countries around the world and is known to be more resistant to neutralizing antibodies compared to other strains. There is evidence that suggests the Lambda variant is both more infectious and resistant to vaccines than the Alpha and/or Gamma variant. __TOC__ Mutations The Lambda genome has the following amino acid mutations, all of which are in the virus's spike protein code: G75V, T76I, Δ246-252, L452Q, F490S, D614G and T859N. File:SARS-CoV-2_Lambda_variant.svg, Amino acid mutations of SARS-CoV-2 Lambda variant plotted on a genome map of SARS-CoV-2 with a focus on the spike. History First samples of the Lambda variant were detected in Peru in August 2020 ...
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SARS-CoV-2 Kappa Variant
Kappa variant is a variant of SARS-CoV-2, the virus that causes COVID-19. It is one of the three sublineages of Pango lineage B.1.617. The SARS-CoV-2 Kappa variant is also known as lineage B.1.617.1 and was first detected in India in December 2020. By the end of March 2021, the Kappa sub-variant accounted for more than half of the sequences being submitted from India. On 1 April 2021, it was designated a Variant Under Investigation (VUI-21APR-01) by Public Health England. Mutations File:SARS-CoV-2_Kappa_variant.svg, Amino acid mutations of SARS-CoV-2 Kappa variant plotted on a genome map of SARS-CoV-2 with a focus on the spike. The Kappa variant has three notable alterations in the amino-acid sequences, all of which are in the virus's spike protein code. The three notable substitutions are: L452R, E484Q, P681R * L452R. The substitution at position 452, a leucine-to-arginine substitution. This exchange confers stronger affinity of the spike protein for the ACE2 receptor a ...
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SARS-CoV-2 Iota Variant
Iota variant, also known as lineage B.1.526, is one of the variants of SARS-CoV-2, the virus that causes COVID-19. It was first detected in New York City in November 2020. The variant has appeared with two notable mutations: the E484K spike mutation, which may help the virus evade antibodies, and the S477N mutation, which may help the virus bind more tightly to human cells. By February 2021, it had spread rapidly in the New York region and accounted for about one in four viral sequences. By 11 April 2021, the variant had been detected in at least 48 U.S. states and 18 countries. Under the simplified naming scheme proposed by the World Health Organization, B.1.526 has been labeled Iota variant, and is considered a ''variant of interest'' (VOI), but not yet a variant of concern. Mutations The Iota (B.1.526) genome contains the following amino-acid mutations, all of which are in the virus's spike protein code: L5F, T95I, D253G, E484K, D614G and A701V. File:SARS-CoV-2_Iota_vari ...
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SARS-CoV-2 Theta Variant
Theta variant, also known as lineage P.3, is one of the variants of SARS-CoV-2, the virus that causes COVID-19. The variant was first identified in the Philippines on February 18, 2021, when two mutations of concern were detected in Central Visayas. It was detected in Japan on March 12, 2021, when a traveler from the Philippines arrived at Narita International Airport in Tokyo. It is distinct from those first discovered in the United Kingdom, South Africa, and Brazil, and is thought to pose a similar threat. The variant is more resistant to neutralizing antibodies, including those gained through vaccination, like how the South African and Brazilian variants appear to be. Under the simplified naming scheme proposed by the World Health Organization, P.3 has been labeled Theta variant, and was considered a ''variant of interest'' (VOI), but not a variant of concern. As of July 2021, Theta is no longer considered as a variant of interest by the WHO. Classification Naming On Ma ...
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SARS-CoV-2 Zeta Variant
Zeta variant, also known as lineage P.2, is a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in the state of Rio de Janeiro; it harbors the E484K mutation, but not the N501Y and K417T mutations. It evolved independently in Rio de Janeiro without being directly related to the Gamma variant from Manaus. Under the simplified naming scheme proposed by the World Health Organization, P.2 was labeled "Zeta variant", and was considered a variant of interest (VOI), but not a variant of concern. A second wave was preceded in November 2020 by an increase in the prevalence of the Zeta variant among genetic sequences from São Paulo state, deposited into the GISAID database. As of July 2021, Zeta is no longer considered a variant of interest by the WHO. Mutations The Zeta genome has 3 amino acid mutations: E484K, D614G, and V1176F, all of which are found in the virus's spike protein code. According to the Centers for Disease Control and Prevention T ...
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SARS-CoV-2 Epsilon Variant
Epsilon variant, also known as CAL.20C and referring to two PANGO lineages B.1.427 and B.1.429, is one of the variants of SARS-CoV-2, the virus that causes COVID-19. It was first detected in California, USA in July 2020. As of March 2022, Epsilon is considered as a previously circulating variant of interest by the WHO. It is considered a variant being monitored by the CDC. Mutations The variant has five defining mutations (I4205V and D1183Y in the ORF1ab gene, and S13I, W152C, L452R in the spike protein's S-gene), of which the L452R (previously also detected in other unrelated lineages) was of particular concern. B.1.429 is possibly more transmissible than previous variants circulating locally, but further study is necessary to confirm this. Centers for Disease Control and Prevention (CDC) has listed B.1.429 and the related B.1.427 as " variants of concern", and cites a preprint for saying that they exhibit a ~20% increase in viral transmissibility, that they have a "Signific ...
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SARS-CoV-2 Delta Variant
The Delta variant (B.1.617.2) was a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in India in late 2020. The Delta variant was named on 31 May 2021 and had spread to over 179 countries by 22 November 2021. The World Health Organization (WHO) indicated in June 2021 that the Delta variant was becoming the dominant strain globally. It has mutations in the gene encoding the SARS-CoV-2 coronavirus spike protein, spike protein causing the substitutions T478K, Variants of SARS-CoV-2#P681R, P681R and Variants of SARS-CoV-2#L452R, L452R, which are known to affect transmissibility of the virus as well as whether it can be neutralised by antibodies for previously circulating variants of the COVID-19 virus. In August 2021, Public Health England (PHE) reported secondary attack rate in household contacts of non-travel or unknown cases for Delta to be 10.8% ''vis-à-vis'' 10.2% for the SARS-CoV-2 Alpha variant, Alpha variant; the case fatality rate for those ...
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Stanford University
Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is considered among the most prestigious universities in the world. Stanford was founded in 1885 by Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Leland Stanford was a U.S. senator and former governor of California who made his fortune as a railroad tycoon. The school admitted its first students on October 1, 1891, as a coeducational and non-denominational institution. Stanford University struggled financially after the death of Leland Stanford in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, provost of Stanford Frederick Terman inspired and supported faculty and graduates' entrepreneu ...
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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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BBC News
BBC News is an operational business division of the British Broadcasting Corporation (BBC) responsible for the gathering and broadcasting of news and current affairs in the UK and around the world. The department is the world's largest broadcast news organisation and generates about 120 hours of radio and television output each day, as well as online news coverage. The service maintains 50 foreign news bureaus with more than 250 correspondents around the world. Deborah Turness has been the CEO of news and current affairs since September 2022. In 2019, it was reported in an Ofcom report that the BBC spent £136m on news during the period April 2018 to March 2019. BBC News' domestic, global and online news divisions are housed within the largest live newsroom in Europe, in Broadcasting House in central London. Parliamentary coverage is produced and broadcast from studios in London. Through BBC English Regions, the BBC also has regional centres across England and national news c ...
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