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SARS-CoV-2 Epsilon Variant
Epsilon variant, also known as CAL.20C and referring to two PANGO lineages B.1.427 and B.1.429, is one of the variants of SARS-CoV-2, the virus that causes COVID-19. It was first detected in California, USA in July 2020. As of March 2022, Epsilon is considered as a previously circulating variant of interest by the WHO. It is considered a variant being monitored by the CDC. Mutations The variant has five defining mutations (I4205V and D1183Y in the ORF1ab gene, and S13I, W152C, L452R in the spike protein's S-gene), of which the L452R (previously also detected in other unrelated lineages) was of particular concern. B.1.429 is possibly more transmissible than previous variants circulating locally, but further study is necessary to confirm this. Centers for Disease Control and Prevention (CDC) has listed B.1.429 and the related B.1.427 as " variants of concern", and cites a preprint for saying that they exhibit a ~20% increase in viral transmissibility, that they have a "Signific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epsilon Variant Countries
Epsilon (, ; uppercase , lowercase or lunate ; el, έψιλον) is the fifth letter of the Greek alphabet, corresponding phonetically to a mid front unrounded vowel or . In the system of Greek numerals it also has the value five. It was derived from the Phoenician letter He . Letters that arose from epsilon include the Roman E, Ë and Ɛ, and Cyrillic Е, È, Ё, Є and Э. The name of the letter was originally (), but it was later changed to ( 'simple e') in the Middle Ages to distinguish the letter from the digraph , a former diphthong that had come to be pronounced the same as epsilon. The uppercase form of epsilon is identical to Latin E but has its own code point in Unicode: . The lowercase version has two typographical variants, both inherited from medieval Greek handwriting. One, the most common in modern typography and inherited from medieval minuscule, looks like a reversed number "3" and is encoded . The other, also known as lunate or uncial epsilon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanford University
Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is considered among the most prestigious universities in the world. Stanford was founded in 1885 by Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Leland Stanford was a U.S. senator and former governor of California who made his fortune as a railroad tycoon. The school admitted its first students on October 1, 1891, as a coeducational and non-denominational institution. Stanford University struggled financially after the death of Leland Stanford in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, provost of Stanford Frederick Terman inspired and supported faculty and graduates' entrepreneu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SARS-CoV-2 Gamma Variant
The Gamma variant (P.1) was one of the variants of SARS-CoV-2, the virus that causes COVID-19. This variant of SARS-CoV-2 has been named lineage P.1 and has 17 amino acid substitutions, ten of which in its spike protein, including these three designated to be of particular concern: N501Y, E484K and K417T. This variant of SARS-CoV-2 was first detected by the National Institute of Infectious Diseases (NIID) of Japan, on 6 January 2021 in four people who had arrived in Tokyo having visited Amazonas, Brazil, four days earlier. It was subsequently declared to be in circulation in Brazil. Under the simplified naming scheme proposed by the World Health Organization, P.1 has been labeled Gamma variant, and is currently considered a variant of concern. Gamma caused widespread infection in early 2021 in the city of Manaus, the capital of Amazonas, although the city had already experienced widespread infection in May 2020, with a study indicating high seroprevalence of antibodies for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SARS-CoV-2 Beta Variant
The Beta variant, (B.1.351), was a variant of SARS-CoV-2, the virus that causes COVID-19. One of several SARS-CoV-2 variants initially believed to be of particular importance, it was first detected in the Nelson Mandela Bay metropolitan area of the Eastern Cape province of South Africa in October 2020, which was reported by the country's health department on 18 December 2020. Phylogeographic analysis suggests this variant emerged in the Nelson Mandela Bay area in July or August 2020. The World Health Organization labelled the variant as Beta variant, not to replace the scientific name but as a name for the public to commonly refer to. The WHO considers it to be a variant of concern no longer in circulation. Names The variant is also known as the ''South African variant''. Mutations File:SARS-CoV-2 Beta variant.svg, Amino acid mutations of SARS-CoV-2 Beta variant plotted on a genome map of SARS-CoV-2 with a focus on Spike. There are three mutations of particular interes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SARS-CoV-2 Alpha Variant
The Alpha variant (B.1.1.7) was a Variants of SARS-CoV-2, SARS-CoV-2 variant of concern. It was estimated to be 40–80% more Transmission (medicine), transmissible than the Wild type, wild-type SARS-CoV-2 (with most estimates occupying the middle to higher end of this range). It was first detected in November 2020 from a sample taken in September in the United Kingdom, and began to spread quickly by mid-December, around the same time as infections surged. This increase is thought to be at least partly because of one or more mutations in the virus' coronavirus spike protein, spike protein. The variant was also notable for having more mutations than normally seen. By January 2021, more than half of all genomic sequencing of SARS-CoV-2 was carried out in the UK. This had given rise to questions as to how many other important variants were circulating around the world undetected. On 2 February 2021, Public Health England reported that they had detected "[a] limited number of B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GISAID
GISAID (Global Initiative on Sharing Avian Influenza Data) is a global science initiative and primary source established in 2008 that provides open access to genomic data of influenza viruses and the coronavirus responsible for the COVID-19 pandemic. On January 10, 2020, the first whole-genome sequences of SARS-CoV-2 were made available on GISAID, which enabled global responses to the pandemic, including the development of the first vaccines and diagnostic tests to detect SARS-CoV-2. The database has become the world's largest repository for SARS-CoV-2 sequences. GISAID facilitates genomic epidemiology and real-time surveillance to monitor the emergence of new COVID-19 viral strains across the planet. Since its establishment as an alternative to sharing avian influenza data via conventional public-domain archives, GISAID has been recognized for incentivizing rapid exchange of outbreak data during the H1N1 pandemic in 2009, the H7N9 epidemic in 2013, and the COVID-19 pandemic in e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nextstrain
Nextstrain is a collaboration between researchers in Seattle, United States and Basel, Switzerland which provides a collection of open-source tools for visualising the genetics behind the spread of viral outbreaks. Its aim is to support public health measures and surveillance by facilitating understanding of the spread and evolution of pathogens. The Nextstrain platform was begun in 2015. Code developed by Nextstrain is made publicly available, via, for example github.com and its data is available and viewable in accessible form via the pages at the website. Applications According to their website, the Nextstrain team maintains an up-to-date genomic analysis of each of the following pathogens: * Avian influenza * Dengue * Enterovirus D68 * Measles * Mumps * SARS-CoV-2 * Seasonal influenza * Tuberculosis * West Nile virus * West African Ebola 2013-16 * Zika * Monkeypox virus Covid-19 pandemic Nextstrain and its results have been widely quoted during the COVID-19 pandemic. Awar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Santa Clara County Public Health Department
The Santa Clara County Public Health Department (abbreviated SCCPHD; also known as Santa Clara County Public Health or the County of Santa Clara Public Health Department) is the public health agency for Santa Clara County, California, part of the Santa Clara County Health System. Sara Cody is the current Public Health Director and Health Officer of Santa Clara County. History The department was accredited by the Public Health Accreditation Board in March 2016. In 2020, the department was one of the first in the United States to issue a stay-at-home order in response to the COVID-19 pandemic. References External links * {{Official website, https://publichealth.sccgov.org/ County government agencies in California Public Health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ... ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
California Department Of Public Health
The California Department of Public Health (CDPH) is the state department responsible for public health in California. It is a subdivision of the California Health and Human Services Agency. It enforces some of the laws in the California Health and Safety Codes, notably the licensing of some types of healthcare facilities. One of its functions is to oversee vital records operations throughout the state. On August 9, 2020, Dr. Sonia Y. Angell resigned as the CDPH Director and State Public Health Officer. Governor Gavin Newsom indicated Angell's resignation was related to data issues with the California Reportable Disease Information Exchange (CalREDIE) system that resulted in nearly 300,000 backlogged COVID-19 test results. On August 10, 2020, Sandra Shewry was appointed as acting director and Dr. Erica Pan, California state epidemiologist, was named acting state public health officer. On December 7, 2020, Governor Gavin Newsom announced Tomás Aragón, MD, DrPH as the next ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California, San Francisco
The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It conducts research and teaching in medical and biological sciences. UCSF was founded as Toland Medical College in 1864. in 1873, it became affiliated with the University of California as its Medical Department. In the same year, it incorporated the California College of Pharmacy and in 1881 it established a dentistry school. Its facilities were located in both Berkeley and San Francisco. In 1964, the school gained full administrative independence as a campus of the UC system, headed by its own chancellor, and in 1970 it gained its current name. Historically based at Parnassus Heights with satellite facilities throughout the city, UCSF developed a second major campus in the newly redeveloped Mission Bay district in the early 2000s. '' U.S. N ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Press Release
A press release is an official statement delivered to members of the news media for the purpose of providing information, creating an official statement, or making an announcement directed for public release. Press releases are also considered a primary source, meaning they are original informants for information. A press release is traditionally composed of nine structural elements, including a headline, dateline, introduction, body, and other components. Press releases are typically delivered to news media electronically, ready to use, and often subject to "do not use before" time, known as a news embargo. A special example of a press release is a communiqué (), which is a brief report or statement released by a public agency. A communiqué is typically issued after a high-level meeting of international leaders. Using press release material can benefit media corporations because they help decrease costs and improve the amount of material a media firm can output in a cer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scripps Research
Scripps Research, previously known as The Scripps Research Institute (TSRI), is a nonprofit American medical research facility that focuses on research and education in the biomedical sciences. Headquartered in San Diego, California, the institute has over 170 laboratories employing 2,100 scientists, technicians, graduate students, and administrative and other staff, making it the largest private, non-profit biomedical research organization in the United States and among the largest in the world. The institute holds over 1,100 patents, has produced 11 FDA-approved therapeutics, and has generated over 50 spin-off companies. According to the 2017 Nature Innovation Index, Scripps Research is the #1 most influential research institution in the world. The Scripps Research graduate program is ranked 9th nationally in the biological sciences, 6th for organic chemistry, and 6th for biochemistry. In 2022, their Jupiter, FL campus became a part of the University of Florida. Jupiter-based ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
