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Syrette
A syrette is a single-use device for injecting liquid through a needle. It is similar to a syringe except that it has a sealed squeeze tube instead of a rigid tube and piston. It was developed by the pharmaceutical manufacturer E.R. Squibb & Sons (eventually merged into the current day Bristol-Myers Squibb) just prior to World War II (WWII). In WWII, the morphine syrette was included in first aid kits. It had a wire loop with a guard at the end of a hollow needle that was used to break a seal where the needle was attached to the tube. The wire loop was then removed and the needle was inserted under the skin at a shallow angle and the tube slowly squeezed from the sealed end (see subcutaneous injection). After injection the used tube was often pinned to the receiving soldier's collar to inform others of the dose administered. The syrette was adopted for use by the United States Army in 1940. The US military also distributed atropine in syrettes. Chemical treatment was subsequen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Syringe
A syringe is a simple reciprocating pump consisting of a plunger (though in modern syringes, it is actually a piston) that fits tightly within a cylindrical tube called a barrel. The plunger can be linearly pulled and pushed along the inside of the tube, allowing the syringe to take in and expel liquid or gas through a discharge orifice at the front (open) end of the tube. The open end of the syringe may be fitted with a hypodermic needle, a nozzle or tubing to direct the flow into and out of the barrel. Syringes are frequently used in clinical medicine to administer injections, infuse intravenous therapy into the bloodstream, apply compounds such as glue or lubricant, and draw/measure liquids. There are also prefilled syringes (disposable syringes marketed with liquid inside). The word "syringe" is derived from the Greek σῦριγξ ('' syrinx'', meaning "Pan flute", "tube"). Medical syringes Medical syringes include disposable and safety syringes, injectio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autoinjector
An autoinjector (or auto-injector) is a medical device for injection of a premeasured dose of a particular drug. Most autoinjectors are one-use, disposable, spring-loaded syringes (prefilled syringes). By design, autoinjectors are easy to use and are intended for self-administration by patients, administration by untrained personnel, or easy use by healthcare professionals; they can also overcome the hesitation associated with self-administration using a needle. The site of injection depends on the drug, but it typically is administered into the thigh or the buttocks. Autoinjectors are sharps waste. History Automatic syringes are known since the 1910s, and many spring-loaded devices with needle protectors were patented in the first half of the 20th century, but it was not until 1970s when they became economically feasible to mass-produce (simple syrettes were used instead before). In 2023 an open source autoinjector was developed that could be digitally replicated with a lo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uniject
Uniject is a disposable, pre-filled, single-use syringe which was developed to promote vaccination in developing countries. It was developed by PATH as part of the solution to the problem of delivering vaccines to areas which have insufficient medical workers to meet the needs of traditional, doctor-mediated vaccination programs. History The Uniject was invented by PATH in 1987. In 2003 PATH accepted a Tech Award from The Tech Museum of Innovation for its development of the Uniject. Use To activate the device, the user would first shake the device to homogenize the liquid suspension. Then, the tamper-evident seal would be twisted. After that, with "a firm, rapid motion" the needle shield would be pushed into the port until the "gap between the needle shield and port closes completely". To actually use the device, the needle shield needs to be removed, exposing the needle. The user would then push the needle into the skin. Almost simultaneously, the reservoir would be pushed down i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United Kingdom
The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of European mainland, the continental mainland. It comprises England, Scotland, Wales and Northern Ireland. The UK includes the island of Great Britain, the north-eastern part of the island of Ireland, and most of List of islands of the United Kingdom, the smaller islands within the British Isles, covering . Northern Ireland shares Republic of Ireland–United Kingdom border, a land border with the Republic of Ireland; otherwise, the UK is surrounded by the Atlantic Ocean, the North Sea, the English Channel, the Celtic Sea and the Irish Sea. It maintains sovereignty over the British Overseas Territories, which are located across various oceans and seas globally. The UK had an estimated population of over 68.2 million people in 2023. The capital and largest city of both England and the UK is London. The cities o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Papaveretum
Papaveretum ( BAN) is a preparation containing a mixture of hydrochloride salts of opium alkaloids. Since 1993, papaveretum has been defined in the British Pharmacopoeia (BP) as a mixture of 253 parts morphine hydrochloride, 23 parts papaverine hydrochloride, and 20 parts codeine hydrochloride. It is commonly marketed to medical agencies under the trade name Omnopon. Although the use of papaveretum is now relatively uncommon following the wide availability of single-component opiates and synthetic opioids (e.g. pethidine), it is still used to relieve moderate to severe pain and for pre-operative sedation. In clinical settings, papaveretum is usually administered to patients via subcutaneous, intramuscular, or intravenous routes. Additionally, the morphine syrettes found in combat medical kits issued to military personnel actually contain Omnopon. Prior to 1993, papaveretum also contained noscapine, though this component was removed from the BP formulation due to the genotoxic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morphine
Morphine, formerly also called morphia, is an opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies (''Papaver somniferum''). It is mainly used as an analgesic (pain medication). There are multiple methods used to administer morphine: oral; sublingual administration, sublingual; via inhalation; intramuscular, injection into a muscle, Subcutaneous injection, injection under the skin, or injection into the spinal cord area; transdermal; or via rectal administration, rectal suppository. It acts directly on the central nervous system (CNS) to induce analgesia and alter perception and emotional response to pain. Physical and psychological dependence and tolerance may develop with repeated administration. It can be taken for both acute pain and chronic pain and is frequently used for pain from myocardial infarction, kidney stones, and during Childbirth, labor. Its maximum effect is reached after about 20 minutes when administ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tube (container)
A tube, squeeze tube, or collapsible tube is a collapsible Packaging, package which can be used for viscous liquids such as toothpaste, artist's paint, adhesive, caulk, ointment, & ointments. Basically, a tube is a cylindrical, hollow piece with a round or oval profile, made of plastic, paperboard, aluminum, or other metal. In general, on one end of the tube body there is a round orifice, which can be closed by different caps and Closure (container), closures. The orifice can be shaped in many different ways: plastic nozzles in various styles and lengths are most typical. The other end is sealed either by welding or by folding. Typical tube sizes range from 3ml to 300ml. Most tubes are designed to be dispensed with hand pressure, but some are used with a tube key at the base to help roll them up. History John Goffe Rand, an American portrait painter, invented the squeezable metal tube in 1841 for paint."Collapsible", ''The New Yorker'', August 6, 1960, p. 20 Toothpaste in a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Piston
A piston is a component of reciprocating engines, reciprocating pumps, gas compressors, hydraulic cylinders and pneumatic cylinders, among other similar mechanisms. It is the moving component that is contained by a cylinder (engine), cylinder and is made gas-tight by piston rings. In an engine, its purpose is to transfer force from expanding gas in the cylinder to the crankshaft via a piston rod and/or connecting rod. In a pump, the function is reversed and force is transferred from the crankshaft to the piston for the purpose of compressing or ejecting the fluid in the cylinder. In some engines, the piston also acts as a valve by covering and uncovering Porting (engine)#Two-stroke porting, ports in the cylinder. __TOC__ Piston engines Internal combustion engines An internal combustion piston engine, internal combustion engine is acted upon by the pressure of the expanding combustion gases in the combustion chamber space at the top of the cylinder. This force then acts dow ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmaceutical Industry
The pharmaceutical industry is a medical industry that discovers, develops, produces, and markets pharmaceutical goods such as medications and medical devices. Medications are then administered to (or self-administered by) patients for curing or preventing disease or for alleviating symptoms of illness or injury. Pharmaceutical companies may deal in generic drugs, branded drugs, or both, in different contexts. Generic materials are without the involvement of intellectual property, whereas branded materials are protected by chemical patents. The industry's various subdivisions include distinct areas, such as manufacturing biologics and total synthesis. The industry is subject to a variety of laws and regulations that govern the patenting, efficacy testing, safety evaluation, and marketing of these drugs. The global pharmaceutical market produced treatments worth a total of $1,228.45 billion in 2020. The sector showed a compound annual growth rate (CAGR) of 1.8% in 2021, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bristol-Myers Squibb
The Bristol-Myers Squibb Company, doing business as Bristol Myers Squibb (BMS), is an American multinational pharmaceutical company. Headquartered in Princeton, New Jersey, BMS is one of the world's largest pharmaceutical companies and consistently ranks on the ''Fortune'' 500 list of the largest U.S. corporations. For fiscal 2022, it had a total revenue of $46.2 billion. Bristol Myers Squibb manufactures prescription pharmaceuticals and biologics in several therapeutic areas, including cancer, HIV/AIDS, cardiovascular disease, diabetes, hepatitis, rheumatoid arthritis, and psychiatric disorders. BMS's primary research and development (R&D) sites are located in Lawrence, New Jersey (formerly Squibb, near Princeton), Summit, New Jersey, formerly HQ of Celgene, New Brunswick, New Jersey; Redwood City, California; and Seville in Spain, with other sites in Devens and Cambridge, Massachusetts; Braine-l'Alleud, Belgium; Tokyo, Japan; Hyderabad; Bangalore, India and Wirr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Subcutaneous Injection
Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion. A subcutaneous injection is administered as a bolus (medicine), bolus into the subcutis, the layer of skin directly below the dermis and Epidermis (skin), epidermis, collectively referred to as the Cutis (anatomy), cutis. The instruments are usually a hypodermic needle and a syringe. Subcutaneous injections are highly effective in administering medications such as insulin, morphine, heroin, diacetylmorphine and goserelin. Subcutaneous administration may be List of medical abbreviations, abbreviated as SC, SQ, subcu, sub-Q, SubQ, or subcut. Subcut is the preferred abbreviation to reduce the risk of misunderstanding and potential errors. Subcutaneous tissue has few blood vessels and so drugs injected into it are intended for slow, sustained rates of absorption, often with some amount of depot injection, depot effect. Compared with other route of administration, routes of ad ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States Army
The United States Army (USA) is the primary Land warfare, land service branch of the United States Department of Defense. It is designated as the Army of the United States in the United States Constitution.Article II, section 2, clause 1 of the United States Constitution (1789).See alsTitle 10, Subtitle B, Chapter 301, Section 3001 It operates under the authority, direction, and control of the United States Secretary of Defense, United States secretary of defense. It is one of the six armed forces and one of the eight uniformed services of the United States. The Army is the most senior branch in order of precedence amongst the armed services. It has its roots in the Continental Army, formed on 14 June 1775 to fight against the British for independence during the American Revolutionary War (1775–1783). After the Revolutionary War, the Congress of the Confederation created the United States Army on 3 June 1784 to replace the disbanded Continental Army.Library of CongressJournals ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
