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Strychnos Toxifera
''Strychnos toxifera'', called bush rope and devil doer, is a species of flowering plant in the genus ''Strychnos'', native to Costa Rica, Panama, Colombia, Ecuador, Venezuela, the Guianas, Brazil, Peru and Bolivia. It is the principal source of calabash or gourd curare Curare ( /kʊˈrɑːri/ or /kjʊˈrɑːri/; ''koo-rah-ree'' or ''kyoo-rah-ree'') is a common name for various alkaloid arrow poisons originating from plant extracts. Used as a paralyzing agent by indigenous peoples in Central and South .... Macusine B is an alkaloid inhibitor of adrenergic alpha-receptors and tryptamine receptors that can be isolated from ''Strychnos toxifera''. References Strychnos, toxifera Plants described in 1838 {{Gentianales-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strychnos
''Strychnos'' is a genus of flowering plants, belonging to the family Loganiaceae (sometimes Strychnaceae). The genus includes about 100 accepted species of trees and lianas, and more than 200 that are as yet unresolved. The genus is widely distributed around the world's tropics and is noted for the presence of poisonous indole alkaloids in the roots, stems and leaves of various species. Among these alkaloids are the well-known and virulent poisons strychnine and curare. Etymology The name ''strychnos'' was applied by Pliny the Elder in his '' Natural History'' to ''Solanum nigrum''. The word is derived from the Ancient Greek στρύχνον (''strúkhnon'') – "acrid", "bitter". The meaning of the word ''strychnos'' was not fixed in Ancient Greece, where it could designate a variety of different plants having in common the property of toxicity. Distribution The genus has a pantropical distribution. Taxonomy The genus is divided into 12 sections, though it is conceded that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lindl
John Lindley FRS (5 February 1799 – 1 November 1865) was an English botanist, gardener and orchidologist. Early years Born in Catton, near Norwich, England, John Lindley was one of four children of George and Mary Lindley. George Lindley was a nurseryman and pomologist and ran a commercial nursery garden. Although he had great horticultural knowledge, the undertaking was not profitable and George lived in a state of indebtedness. As a boy he would assist in the garden and also collected wild flowers he found growing in the Norfolk countryside. Lindley was educated at Norwich School. He would have liked to go to university or to buy a commission in the army but the family could not afford either. He became Belgian agent for a London seed merchant in 1815. At this time Lindley became acquainted with the botanist William Jackson Hooker who allowed him to use his botanical library and who introduced him to Sir Joseph Banks who offered him employment as an assistant in his herba ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Guianas
The Guianas, sometimes called by the Spanish loan-word ''Guayanas'' (''Las Guayanas''), is a region in north-eastern South America which includes the following three territories: * French Guiana, an overseas department and region of France * Guyana, formerly known as British Guiana from 1831 until 1966, after the colonies of Berbice, Essequibo, and Demerara, taken from the Netherlands in 1814, were merged into a single colony * Suriname, formerly Dutch Guiana, until 1814 together with Berbice, Essequibo and Demerara In the wider context, the Guianas also includes the following two territories: * Guayana Region in eastern Venezuela ( Amazonas, Bolívar, and Delta Amacuro states), formerly the Guayana Province, alternatively known as Spanish Guayana * State of Amapá in northern Brazil, known as Portuguese Guiana (or Brazilian Guiana) History Pre-colonial period Before the arrival of European colonials, the Guianas were populated by scattered bands of native Arawak ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Curare
Curare ( /kʊˈrɑːri/ or /kjʊˈrɑːri/; ''koo-rah-ree'' or ''kyoo-rah-ree'') is a common name for various alkaloid arrow poisons originating from plant extracts. Used as a paralyzing agent by indigenous peoples in Central and South America for hunting and for therapeutic purposes, curare only becomes active when it contaminates a wound. These poisons cause weakness of the skeletal muscles and, when administered in a sufficient dose, eventual death by asphyxiation due to paralysis of the diaphragm. Curare is prepared by boiling the bark of one of the dozens of plant sources, leaving a dark, heavy paste that can be applied to arrow or dart heads. In medicine, curare has been used as a treatment for tetanus or strychnine poisoning and as a paralyzing agent for surgical procedures. History The word 'curare' is derived from ''wurari'', from the Carib language of the Macusi of Guyana. It has its origins in the Carib phrase "mawa cure" meaning of the Mawa vine, scienti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids xumuk.ru Alkaloids are produced by a large variety of organisms including , , Medicinal plant, plants, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenergic
Adrenergic means "working on adrenaline (epinephrine) or noradrenaline (norepinephrine)" (or on their receptors). When not further qualified, it is usually used in the sense of enhancing or mimicking the effects of epinephrine and norepinephrine in the body. *Adrenergic nervous system, a part of the autonomic nervous system that uses epinephrine or norepinephrine as its neurotransmitter Regarding proteins: * Adrenergic receptor, a receptor type for epinephrine and norepinephrine; subtypes include α1, α2, β1, β2, and β3 receptors * Adrenergic transporter (norepinephrine transporter), a protein transporting norepinephrine from the synaptic cleft into nerve cells Regarding pharmaceutical drugs: * Adrenergic receptor agonist, a type of drug activating one or more subtypes of adrenergic receptors ** This includes drugs regulating blood pressure and antiasthmatic drugs. * Adrenergic receptor antagonist, a type of drug blocking one or more subtypes of adrenergic receptors ** This ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tryptamine
Tryptamine is an indolamine metabolite of the essential amino acid, tryptophan. The chemical structure is defined by an indole ─ a fused benzene and pyrrole ring, and a 2-aminoethyl group at the second carbon (third aromatic atom, with the first one being the heterocyclic nitrogen). The structure of tryptamine is a shared feature of certain aminergic neuromodulators including melatonin, serotonin, bufotenin and psychedelic derivatives such as dimethyltryptamine (DMT), psilocybin, psilocin and others. Tryptamine has been shown to activate trace amine-associated receptors expressed in the mammalian brain, and regulates the activity of dopaminergic, serotonergic and glutamatergic systems. In the human gut, symbiotic bacteria convert dietary tryptophan to tryptamine, which activates 5-HT4 receptors and regulates gastrointestinal motility. Multiple tryptamine-derived drugs have been developed to treat migraines, while trace amine-associated receptors are being explored as a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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