Streptomyces Misakiensis
''Kitasatospora misakiensis'' is a bacterium species from the genus of ''Kitasatospora'' which has been isolated from soil in Japan.Deutsche Sammlung von Mikroorganismen und Zellkulturenbr>/ref> ''Kitasatospora misakiensis'' produces tubermycin A, tubermycin B, misakimycin and the endothelin receptor antagonist An endothelin receptor antagonist (ERA) is a drug that blocks endothelin receptors. Three main kinds of ERAs exist: * selective ETA receptor antagonists ( sitaxentan, ambrisentan, atrasentan, BQ-123, zibotentan, edonentan), which affect e ... BE-18257B. Further reading * * * * * * References External linksType strain of ''Streptomyces misakiensis'' at Bac''Dive'' - the Bacterial Diversity Metadatabase Streptomycineae Bacteria described in 1961 {{Actinobacteria-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Kitasatospora
''Kitasatospora'' is an Actinobacteria genus in the family Streptomycetaceae. The genus name comes from Shibasaburo Kitasato, a Japanese bacteriologist. Species ''Kitasatospora'' comprises the following genera: * '' K. aburaviensis'' (Nishimura et al. 1957) Labeda et al. 2017 * '' K. acidiphila'' Kim et al. 2020 * '' K. albolonga'' (Tsukiura et al. 1964) Labeda et al. 2017 * '' K. arboriphila'' Groth et al. 2004 * '' K. atroaurantiaca'' (Nakagaito et al. 1993) Li et al. 2009 * '' K. aureofaciens'' (Duggar 1948) Labeda et al. 2017 * '' K. azatica'' corrig. (Nakagaito et al. 1993) Zhang et al. 1997 * '' K. cheerisanensis'' Chung et al. 1999 * '' K. cineracea'' Tajima et al. 2001 * '' K. cinereorecta'' (Terekhova and Preobrazhenskaya 1986) Labeda et al. 2017 * '' K. cystarginea'' corrig. Kusakabe and Isono 1992 * "'' K. fumigata''" (Frommer 1959) Labeda et al. 2017 * '' K. gansuensis'' Groth et al. 2004 * '' K. griseola'' corrig. Takahashi et al. 1985 * '' K. herbaricolor'' (K ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Japan
Japan ( ja, 日本, or , and formally , ''Nihonkoku'') is an island country in East Asia. It is situated in the northwest Pacific Ocean, and is bordered on the west by the Sea of Japan, while extending from the Sea of Okhotsk in the north toward the East China Sea, Philippine Sea, and Taiwan in the south. Japan is a part of the Ring of Fire, and spans Japanese archipelago, an archipelago of List of islands of Japan, 6852 islands covering ; the five main islands are Hokkaido, Honshu (the "mainland"), Shikoku, Kyushu, and Okinawa Island, Okinawa. Tokyo is the Capital of Japan, nation's capital and largest city, followed by Yokohama, Osaka, Nagoya, Sapporo, Fukuoka, Kobe, and Kyoto. Japan is the List of countries and dependencies by population, eleventh most populous country in the world, as well as one of the List of countries and dependencies by population density, most densely populated and Urbanization by country, urbanized. About three-fourths of Geography of Japan, the c ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Deutsche Sammlung Von Mikroorganismen Und Zellkulturen
The Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH (German: ''Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH''), located in Braunschweig, is a research infrastructure in the Leibniz Association. Also the DSMZ is the world's most diverse collection of bioresources (status 2021: 75,000 bioresources). These include microorganisms (including more than 32,000 bacterial strains, 690 archaeal strains, 7,000 strains of yeasts and fungi) as well as more than 840 human and animal cell cultures, over 1. 500 plant viruses, over 940 bacteriophages, and 250 plasmids (status 2021). Since 2010, the scientific director of the Leibniz Institute DSMZ has been Jörg Overmann, a microbiologist with a PhD. He holds a professorship in microbiology at the Technical University of Braunschweig. Since August 2018, he has led the institute in a dual leadership with Bettina Fischer as administrative director. History Structure ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Endothelin Receptor Antagonist
An endothelin receptor antagonist (ERA) is a drug that blocks endothelin receptors. Three main kinds of ERAs exist: * selective ETA receptor antagonists ( sitaxentan, ambrisentan, atrasentan, BQ-123, zibotentan, edonentan), which affect endothelin A receptors. * dual antagonists (bosentan, macitentan, tezosentan), which affect both endothelin A and B receptors. * selective ETB receptor antagonists (BQ-788 and A192621) which affect endothelin B receptors are used in research but have not yet reached the clinical trial stage. Sitaxentan, ambrisentan and bosentan are mainly used for the treatment of pulmonary arterial hypertension, while atrasentan is an experimental anti-cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ... drug. References {{cardiova ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Streptomycineae
The ''Streptomycetaceae'' are a family of ''Actinomycetota'', making up the monotypic order ''Streptomycetales''. It includes the important genus '' Streptomyces''. This was the original source of many antibiotics, namely streptomycin, the first antibiotic against tuberculosis. Genomics Sequence alignments of actinomycetotal genomes have led to the identification of three conserved signature indels which are unique to the order Streptomycetales. The enzyme PBGD contains a four-amino-acid insertion which is present in all ''Streptomyces'' species and ''Kitasatospora setae'', but not any other Actinomycetota. Similarly, a one- amino-acid insertion is present in a conserved region of adenylate kinase and is found in all ''Streptomyces'' species and '' K. setae'', but is not found in any other Actinomycetota. Five conserved signature proteins have also been identified which are present in various sequenced ''Streptomyces'' species, but not in ''K. setae''; however, as the complete ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |