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Stormie Jones
Stormie Dawn Jones (May 30, 1977 – November 11, 1990) was the world's first recipient of a successful simultaneous heart and liver organ transplant. On February 14, 1984, under the direction of Dr. Thomas E. Starzl, Drs. Byers W. Shaw Jr. and Henry T. Bahnson replaced the six-year-old's heart and liver at the Children's Hospital of Pittsburgh in Pittsburgh, Pennsylvania.New York Times. February 20, 1990New Liver for Stormie Jones Retrieved on July 2, 2007. Stormie had a condition which raised her blood cholesterol to 10 times normal levels. The condition, a severe form of familial hypercholesterolemia,Time Magazine. Mar. 26, 1984A One-in-a-Million Worst Case Retrieved on July 2, 2007. and the resultant high levels of low density lipoprotein that damaged her organs, gave her two heart attacks when she was six years old.New York Times. October 15, 1985Young Texas transplant patient is among many aided by Nobel research Retrieved on July 2, 2007. The case showed that th ...
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Borger, Texas
Borger ( ) is the largest city in Hutchinson County, Texas, United States. The population was 12,551 at the 2020 census. Borger is named for businessman Asa Philip "Ace" Borger, who also established the Hutchinson County seat of Stinnett and several other small towns in Texas and Oklahoma. History Ace Borger and his business partner John R. Miller purchased a townsite near the Canadian River in March 1926 after the discovery of oil in the vicinity. Within a few months, the boomtown had swollen to a population of 45,000, most lured by sensational advertising and " black gold". In October 1926, the city charter was adopted, and Miller was elected mayor. By this time, the Panhandle & Santa Fe Railway had completed the spur line to Borger, a post office had opened, and a school district was established. The boomtown of Borger soon had steam-generated electricity, telephone service, a hotel, and a jail. Regionalist artist Thomas Hart Benton depicted this period of Borger i ...
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Joseph L
Joseph is a common male given name, derived from the Hebrew Yosef (יוֹסֵף). "Joseph" is used, along with "Josef", mostly in English, French and partially German languages. This spelling is also found as a variant in the languages of the modern-day Nordic countries. In Portuguese and Spanish, the name is "José". In Arabic, including in the Quran, the name is spelled '' Yūsuf''. In Persian, the name is "Yousef". The name has enjoyed significant popularity in its many forms in numerous countries, and ''Joseph'' was one of the two names, along with ''Robert'', to have remained in the top 10 boys' names list in the US from 1925 to 1972. It is especially common in contemporary Israel, as either "Yossi" or "Yossef", and in Italy, where the name "Giuseppe" was the most common male name in the 20th century. In the first century CE, Joseph was the second most popular male name for Palestine Jews. In the Book of Genesis Joseph is Jacob's eleventh son and Rachel's first son, and k ...
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People From Pittsburgh
This article contains a list of notable people who were born or lived a significant amount of time in Pittsburgh, Pennsylvania. The city of Pittsburgh is the second-largest city and the center of the second largest metro area in the U.S. Commonwealth of Pennsylvania. Artists Actresses * Tina Benko * Julie Benz * Lori Cardille * Caitlin Clarke * Dolores Costello * Marpessa Dawn * Barbara Feldon * Rita Gam * Elizabeth Hartman * Gillian Jacobs * Cherie Johnson * Kimmarie Johnson * Shirley Jones * Lorelei King * Christine Laitta * Heather Mazur * Mitzi McCall * Judith McConnell * Anisha Nagarajan * Evelyn Nesbit * Sandra Dee Robinson * Margot Rose * Zelda Rubinstein * Lillian Russell * Rena Sofer * Sam Sorbo * Maddie Ziegler * Lisa Emery Actors * F. Murray Abraham * Tom Atkins * Carl Betz * Christian Borle * Don Brockett * Steve Byrne * Ted Cassidy * David Conrad * Maurice Costello * Rusty Cundieff * John Davidson * Jack Dodson * Charles Esten * ...
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People From Borger, Texas
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ...
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American Children
Youth in the United States can be regarded as one age group in the demographics of the United States. In 2010 it was estimated that 20.2% of the population of the United States were 0–14 years old (30,305,704 females and 31,639,127 males). Concerns from parents According to a survey of parents in 2011, the issues of greatest concern about children are as follows, with percentages of adults who rate each item as a "big problem":
5th annual survey by C.S. Mott Children’s Hospital, the University of Michigan Department of Pediatrics and Communicable Diseases, and the University of Michigan Child Health Evaluation and Research (CHEAR) Unit. # Childhood obesity in the United St ...
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Liver Transplant Recipients
The liver is a major organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and biochemicals necessary for digestion and growth. In humans, it is located in the right upper quadrant of the abdomen, below the diaphragm. Its other roles in metabolism include the regulation of glycogen storage, decomposition of red blood cells, and the production of hormones. The liver is an accessory digestive organ that produces bile, an alkaline fluid containing cholesterol and bile acids, which helps the breakdown of fat. The gallbladder, a small pouch that sits just under the liver, stores bile produced by the liver which is later moved to the small intestine to complete digestion. The liver's highly specialized tissue, consisting mostly of hepatocytes, regulates a wide variety of high-volume biochemical reactions, including the synthesis and breakdown of small and complex molecules, many o ...
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Heart Transplant Recipients
The heart is a muscular organ in most animals. This organ pumps blood through the blood vessels of the circulatory system. The pumped blood carries oxygen and nutrients to the body, while carrying metabolic waste such as carbon dioxide to the lungs. In humans, the heart is approximately the size of a closed fist and is located between the lungs, in the middle compartment of the chest. In humans, other mammals, and birds, the heart is divided into four chambers: upper left and right atria and lower left and right ventricles. Commonly the right atrium and ventricle are referred together as the right heart and their left counterparts as the left heart. Fish, in contrast, have two chambers, an atrium and a ventricle, while most reptiles have three chambers. In a healthy heart blood flows one way through the heart due to heart valves, which prevent backflow. The heart is enclosed in a protective sac, the pericardium, which also contains a small amount of fluid. The wall of t ...
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1990 Deaths
Year 199 ( CXCIX) was a common year starting on Monday (link will display the full calendar) of the Julian calendar. At the time, it was sometimes known as year 952 '' Ab urbe condita''. The denomination 199 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Mesopotamia is partitioned into two Roman provinces divided by the Euphrates, Mesopotamia and Osroene. * Emperor Septimius Severus lays siege to the city-state Hatra in Central-Mesopotamia, but fails to capture the city despite breaching the walls. * Two new legions, I Parthica and III Parthica, are formed as a permanent garrison. China * Battle of Yijing: Chinese warlord Yuan Shao defeats Gongsun Zan. Korea * Geodeung succeeds Suro of Geumgwan Gaya, as king of the Korean kingdom of Gaya (traditional date). By topic Religion * Pope Zephyrinus succeeds Pope Victor I, as ...
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1977 Births
Events January * January 8 – Three bombs explode in Moscow within 37 minutes, killing seven. The bombings are attributed to an Armenian separatist group. * January 10 – Mount Nyiragongo erupts in eastern Zaire (now the Democratic Republic of the Congo). * January 17 ** 49 marines from the and are killed as a result of a collision in Barcelona harbour, Spain. * January 18 ** Scientists identify a previously unknown bacterium as the cause of the mysterious Legionnaires' disease. ** Australia's worst railway disaster at Granville, a suburb of Sydney, leaves 83 people dead. ** SFR Yugoslavia Prime minister Džemal Bijedić, his wife and 6 others are killed in a plane crash in Bosnia and Herzegovina. * January 19 – An Ejército del Aire CASA C-207C Azor (registration T.7-15) plane crashes into the side of a mountain near Chiva, on approach to Valencia Airport in Spain, killing all 11 people on board. * January 20 – Jimmy Carter is sworn in as the 39th Pres ...
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Immunosuppressant
Immunosuppressive drugs, also known as immunosuppressive agents, immunosuppressants and antirejection medications, are drugs that inhibit or prevent activity of the immune system. Classification Immunosuppressive drugs can be classified into five groups: * glucocorticoids * cytostatics * antibodies * drugs acting on immunophilins * other drugs Glucocorticoids In pharmacologic (supraphysiologic) doses, glucocorticoids, such as prednisone, dexamethasone, and hydrocortisone are used to suppress various allergic, inflammatory, and autoimmune disorders. They are also administered as posttransplantory immunosuppressants to prevent the acute transplant rejection and graft-versus-host disease. Nevertheless, they do not prevent an infection and also inhibit later reparative processes. Immunosuppressive mechanism Glucocorticoids suppress cell-mediated immunity. They act by inhibiting genes that code for the cytokines Interleukin 1 (IL-1), IL-2, IL-3, IL-4, IL-5, IL- ...
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LDL-cholesterol
Low-density lipoprotein (LDL) is one of the five major groups of lipoprotein that transport all fat molecules around the body in extracellular water. These groups, from least dense to most dense, are chylomicrons (aka ULDL by the overall density naming convention), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL delivers fat molecules to cells. LDL is involved in atherosclerosis, a process in which it is oxidized within the walls of arteries. Overview Lipoproteins transfer lipids (fats) around the body in the extracellular fluid, making fats available to body cells for receptor-mediated endocytosis. Lipoproteins are complex particles composed of multiple proteins, typically 80–100 proteins per particle (organized by a single apolipoprotein B for LDL and the larger particles). A single LDL particle is about 220–275 angstroms in diameter, typically transporting 3,000 to 6,000 fat ...
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Nobel Prize In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2022, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates, 214 men and 12 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucidati ...
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