Sterubin
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Sterubin
Sterubin (7-methoxy-3',4',5-trihydroxyflavanone) is a bitter-masking flavanone extracted from Yerba Santa (''Eriodictyon californicum'') a plant growing in America. Sterubin is one of the four flavanones identified by Symrise in this plant which elicit taste-modifying properties. The others are homoeriodictyol, its sodium salt, and eriodictyol Eriodictyol is a bitter-masking flavanone, a flavonoid extracted from yerba santa (''Eriodictyon californicum''), a plant native to North America. Eriodictyol is one of the four flavanones identified in this plant as having taste-modifying proper .... Recent research has demonstrated some neuroprotective properties of Sterubin ''in vitro'', but more research is needed before it can be considered a true drug candidate.Batya Swift Yasgur Medscape. February 2019. References O-methylated flavanones Bitter-masking compounds Taste modifiers Catechols {{aromatic-stub ...
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Eriodictyon Californicum
''Eriodictyon californicum'' is a species of plant within the family Boraginaceae. It is also known as yerba santa (sacred herb), mountain balm, bear's weed, gum bush, gum plant, and consumptive weed.Patricia Kaminski and Richard Katz.Yerba Santa ''Eriodictyon californicum'' Flower Essence Society. Less common names include Herbe des Montagnes, Herbe à Ourse, Herbe Sacrée, Herbe Sainte, Hierba Santa, Holy Herb, and Tarweed. Distribution It is native to California and Oregon, where it grows in several types of habitats, including chaparral and coast redwood forests. Description ''Eriodictyon californicum'' is an evergreen aromatic shrub with woody rhizomes, typically found in clonal stands growing to a height of 3 to 4 feet (1+ meter). The dark green, leathery leaves are narrow, oblong to lanceolate, and up to 15 centimeters in length. Foliage and twigs are covered with shiny resin and are often dusted with black fungi, ''Heterosporium californicum''. It is similar to its Sou ...
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Flavanone
The flavanones, a type of flavonoids, are various aromatic, colorless ketones derived from flavone that often occur in plants as glycosides. List of flavanones * Blumeatin * Butin * Eriodictyol * Hesperetin * Hesperidin * Homoeriodictyol * Isosakuranetin * Naringenin * Naringin * Pinocembrin * Poncirin * Sakuranetin * Sakuranin * Sterubin * Pinostrobin Metabolism The enzyme chalcone isomerase uses a chalcone-like compound to produce a flavanone. Flavanone 4-reductase is an enzyme that uses (2''S'')-flavan-4-ol The flavan-4-ols (3-deoxyflavonoids) are flavone-derived alcohols and a family of flavonoids. Flavan-4-ols are colorless precursor compounds that polymerize to form red phlobaphene pigments. They can be found in the sorghum. Glycosides (abacopteri ... and NADP+ to produce (2''S'')-flavanone, NADPH, and H+. Synthesis Numerous methods exist for the enantioselective chemical and biochemical synthesis of flavanones and related compounds. References External links ...
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Americas
The Americas, which are sometimes collectively called America, are a landmass comprising the totality of North and South America. The Americas make up most of the land in Earth's Western Hemisphere and comprise the New World. Along with their associated islands, the Americas cover 8% of Earth's total surface area and 28.4% of its land area. The topography is dominated by the American Cordillera, a long chain of mountains that runs the length of the west coast. The flatter eastern side of the Americas is dominated by large river basins, such as the Amazon, St. Lawrence River–Great Lakes basin, Mississippi, and La Plata. Since the Americas extend from north to south, the climate and ecology vary widely, from the arctic tundra of Northern Canada, Greenland, and Alaska, to the tropical rain forests in Central America and South America. Humans first settled the Americas from Asia between 42,000 and 17,000 years ago. A second migration of Na-Dene speakers followed later ...
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Symrise
Symrise AG is a major producer of flavours and fragrances with sales of €3.154 billion in 2018. Major competitors include Döhler, Firmenich, Givaudan, International Flavors and Fragrances, and Takasago International. Symrise is a member of the European Flavour Association. In 2021, Symrise was ranked 4th by FoodTalks' Global Top 50 Food Flavours and Fragrances Companies list. History Symrise was founded in 2003 by the merger of Bayer subsidiary Haarmann & Reimer (H&R) and Dragoco, both based in Holzminden, Germany. Haarman & Reimer Haarman & Reimer (H&R) was founded in 1874 by chemists Ferdinand Tiemann and Wilhelm Haarmann after they succeeded in first synthesizing vanillin from coniferin. Holzminden was the site where vanillin was first produced industrially. In 1917, H&R supported Leopold Ružička's unsuccessful three-year project to synthesize irone, a fragrance of violets. In 1953, H&R was acquired by Bayer. Dragoco Dragoco was founded in 1919 by Carl-Wilhelm Gerbe ...
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Homoeriodictyol
Homoeriodictyol is a bitter-masking flavanone extracted from Yerba Santa (''Eriodictyon californicum'') a plant growing in America. Homoeriodictyol (3`-methoxy-4`,5,7-trihydroxyflavanone) is one of the 4 flavanones identified by Symrise in this plant eliciting taste-modifying property: homoeriodictyol sodium salt, eriodictyol and sterubin. Homoeriodictyol Sodium salt elicited the most potent bitter-masking activity by reducing from 10 to 40% the bitterness of salicin, amarogentin, paracetamol and quinine. However no bitter-masking activity was detected with bitter linoleic acid emulsions. According to Symrise's scientists homoeriodictyol sodium salt seems to be a taste-modifier with large potential in food applications and pharmaceuticals. Structural relatives investigation based on eriodictyol and homoeriodictyol, found 2,4-Dihydroxybenzoic acid vanillylamide to elicits bitter-masking activity. At 0.1g/L, this vanillin derivative, was able to reduce the bitterness of a 0.5g/ ...
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Eriodictyol
Eriodictyol is a bitter-masking flavanone, a flavonoid extracted from yerba santa (''Eriodictyon californicum''), a plant native to North America. Eriodictyol is one of the four flavanones identified in this plant as having taste-modifying properties, the other three being homoeriodictyol, its sodium salt, and sterubin. Eriodictyol was also found in the twigs of ''Millettia duchesnei'', in ''Eupatorium arnottianum'', and its glycosides (eriocitrin) in lemons and rose hips The rose hip or rosehip, also called rose haw and rose hep, is the accessory fruit of the various species of rose plant. It is typically red to orange, but ranges from dark purple to black in some species. Rose hips begin to form after pollinat ... (''Rosa canina''). References {{Flavanone Flavanones Bitter-masking compounds Catechols Resorcinols ...
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Taste Modifiers
The gustatory system or sense of taste is the sensory system that is partially responsible for the perception of taste (flavor). Taste is the perception produced or stimulated when a substance in the mouth reacts chemically with taste receptor cells located on taste buds in the oral cavity, mostly on the tongue. Taste, along with olfaction and trigeminal nerve stimulation (registering texture, pain, and temperature), determines flavors of food and other substances. Humans have taste receptors on taste buds and other areas, including the upper surface of the tongue and the epiglottis. The gustatory cortex is responsible for the perception of taste. The tongue is covered with thousands of small bumps called papillae, which are visible to the naked eye. Within each papilla are hundreds of taste buds. The exception to this is the filiform papillae that do not contain taste buds. There are between 2000 and 5000Boron, W.F., E.L. Boulpaep. 2003. Medical Physiology. 1st ed. Elsevier Sc ...
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