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Steps Ahead Members
Step(s) or STEP may refer to: Common meanings * Stairs#Step, Steps, making a staircase * Walking * Dance move * Military step, or march ** Marching Arts Films and television * Steps (TV series), ''Steps'' (TV series), Hong Kong * Step (film), ''Step'' (film), US, 2017 Literature * Steps (novel), ''Steps'' (novel), by Jerzy Kosinski * Systematic Training for Effective Parenting, a book series Music * Step (music), pitch change * Steps (pop group), UK * Step (Kara album), ''Step'' (Kara album), 2011, South Korea ** Step (Kara song), "Step" (Kara song) * Step (Meg album), ''Step'' (Meg album), 2007, Japan * Step (Vampire Weekend song), "Step" (Vampire Weekend song) * Step (ClariS song), "Step" (ClariS song) Organizations * Society of Trust and Estate Practitioners, international professional body for advisers who specialise in inheritance and succession planning * Board on Science, Technology, and Economic Policy of the U.S. National Academies * Solving the E-waste Problem, a UN ...
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Stairs
Stairs are a structure designed to bridge a large vertical distance between lower and higher levels by dividing it into smaller vertical distances. This is achieved as a diagonal series of horizontal platforms called steps which enable passage to the other level by stepping from one to another step in turn. Steps are very typically rectangular. Stairs may be straight, round, or may consist of two or more straight pieces connected at angles. Types of stairs include staircases (also called stairways), ladders, and escalators. Some alternatives to stairs are elevators (also called lifts), stairlifts, inclined moving walkways, and ramps. A stairwell is a vertical shaft or opening that contains a staircase. A flight (of stairs) is an inclined part of a staircase consisting of steps (and their lateral supports if supports are separate from steps). Components and terms A ''stair'', or a ''stairstep'', is one step in a flight of stairs.R.E. Putnam and G.E. Carlson, ''Architectural a ...
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Board On Science, Technology, And Economic Policy
The United States National Academy of Sciences' Board on Science, Technology, and Economic Policy (STEP) is a board of the United States National Academy of Sciences. The mandate of the Board is to integrate understanding of scientific, technological, and economic elements in the formulation of national policies affecting the economic well-being of the United States. The program’s focus is on the dynamics of the macroeconomic and microeconomic variables, their relationship to the industrial structure of the economy, effect on high-technology manufacturing and service sectors, and influence on U.S. scientific and technological advancement through examination of trade, human resources, fiscal, research and development, intellectual property and other policies. Policymakers responsible for these areas in the executive branch and Congress are the audience for the STEP Board’s work in the form of consensus reports, conferences, and workshops. The current Executive Director is Stephe ...
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Staggered Extension Process
The staggered extension process (also referred to as StEP) is a common technique used in biotechnology and molecular biology to create new, mutated genes with qualities of one or more initial genes. The technique itself is a modified polymerase chain reaction with very short (approximately 10 seconds) cycles. In these cycles the elongation of DNA is very quick (only a few hundred base pairs) and synthesized fragments anneal with complementary fragments of other strands. In this way, mutations of the initial genes are shuffled and in the end genes with new combinations of mutations are amplified. The StEP protocol has been found to be useful as a method of directed evolution Directed evolution (DE) is a method used in protein engineering that mimics the process of natural selection to steer proteins or nucleic acids toward a user-defined goal. It consists of subjecting a gene to iterative rounds of mutagenesis ( ... for the discovery of enzymes useful to industry. References ...
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Sustainable Transport Energy For Perth
The Fuel Cell Bus Club comprised the participants of the projects CUTE (2001-2006), ECTOS (2001-2005) and STEP (2001-2005) which were pioneering demonstration projects for fuel cell bus fleets in Europe and Australia. The projects have been successfully completed. There were three buses in each of the 11 cities in the trial. The buses were a Mercedes-Benz Citaro and used hydrogen fuel cells from Ballard Power Systems. At the time they claimed to be the largest fleet of fuel cell buses in the world. The buses were estimated to cost US$ 1.2 million each and have a range of and carry around 70 passengers. Projects CUTE CUTE stands for ''Clean Urban Transport for Europe''. This European Union initiative was responsible for the fuel cell buses in all but two of the cities: Hamburg, London, Barcelona, Stockholm, Porto, Stuttgart, Amsterdam, Luxembourg, and Madrid. It was supported by a consortium of transportation operators, hydrogen infrastructure and fuel cell developers, universi ...
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ISO 10303
ISO 10303 is an ISO standard for the computer-interpretable representation and exchange of product manufacturing information. It is an ASCII-based format. Its official title is: ''Automation systems and integration — Product data representation and exchange''. It is known informally as "STEP", which stands for "Standard for the Exchange of Product model data". ISO 10303 can represent 3D objects in Computer-aided design (CAD) and related information. Overview The objective of the international standard is to provide a mechanism that is capable of describing product data throughout the life cycle of a product, independent from any particular system. The nature of this description makes it suitable not only for neutral file exchange, but also as a basis for implementing and sharing product databases and archiving. STEP can be typically used to exchange data between CAD, computer-aided manufacturing, computer-aided engineering, product data management/enterprise data modelin ...
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STEP Library
STEP (Standard Template for Electronic Publishing) is a standard file format used to distribute Biblical software from various publishers. STEP was conceived in 1995 by Craig Rairdin of Parsons Technology and Jim VanDuzer of Loizeaux Brothers Publishers. Rairdin and VanDuzer formed a consortium of Biblical software publishers called the Bible Software Industry Standards Group (BSISG) to oversee the development of the STEP specification and to develop common tools to be used by developers and publishers interested in implementing STEP compatibility in their programs or publishing books in the STEP format. The STEP logo was originally a trademark of Parsons Technology, Inc., now of FindEx, Inc., the current publisher of QuickVerse Bible Software. Format specification The files use Microsoft's Rich Text Format (RTF) with special STEP tags added. While not fully open format, as was sometimes claimed, the specifications have been publicly released, enabling third parties to write the ...
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STEP (satellite)
The Satellite Test of the Equivalence Principle (STEP) is a proposed () space science experiment to test the equivalence principle of general relativity. The experiment is thought to be sensitive enough to test Einstein's theory of gravity and other theories. The basic configuration is that of a drag-free satellite where an outer shell around an inner test mass is used to block solar wind, atmospheric drag, the Earth's magnetic field and other effects which might disturb the motion of a freely-falling inner object. It is designed for an expected sensitivity of one part in 1018. "Research on the STEP accelerometers began in 1971 at Stanford University, and has been supported since 1977 with NASA funding. STEP has been studied twice by ESA at the Phase-A level and has led two other space agencies (CNES and ASI) to study projects aimed at testing the Equivalence Principle in space. STEP is currently undergoing a Phase A study for NASA's office of Space Science Small Explorer program." ...
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Spherical Tokamak For Energy Production
Spherical Tokamak for Energy Production (STEP) is a spherical tokamak fusion plant concept proposed by the United Kingdom Atomic Energy Authority and funded by UK government. The project is a proposed DEMO-class successor device to the ITER tokamak proof-of-concept of a fusion plant, the most advanced tokamak fusion reactor to date, which is scheduled to achieve a 'burning plasma' in 2035. STEP aims to produce net electricity from fusion on a timescale of 2040. Jacob Rees-Mogg, the UK Secretary of State for Business, Energy and Industrial Strategy, announced West Burton A power station in Nottinghamshire as its site on 3 October 2022 during the Conservative Party Conference. A coal-fired power station at the site ceased production a few days earlier. Plans In September 2019, the United Kingdom announced a planned £200-million (US$248-million) investment to produce a design for STEP. The funding covers the initial five year concept design phase, while the total capital costs are e ...
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Serial Transverse Enteroplasty
Serial transverse enteroplasty (STEP) is a surgical procedure used primarily in the treatment of short bowel syndrome (SBS). In STEP, by making cuts in the intestine and creating a zigzag pattern, surgeons lengthen the amount of bowel available to absorb nutrients. The procedure was first performed in 2003 and more than 100 patients had undergone the surgery by 2013. Background Short bowel syndrome (SBS) is the condition in which a patient cannot absorb adequate nutrients because a portion of the small intestine is damaged or absent. SBS commonly affects pediatric patients who have undergone surgery, such as premature infants with necrotizing enterocolitis and infants with gastrointestinal defects such as gastroschisis. In adults, Crohn's disease is a possible cause of SBS. If they are unable to absorb nutrients in the gut, patients must be given parenteral nutrition (PN) intravenously, but long-term PN can be associated with liver failure. History The procedure was studied by re ...
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Striatal-enriched Protein Tyrosine Phosphatase
Protein tyrosine phosphatase non-receptor type 5 is an enzyme that in humans is encoded by the ''PTPN5'' gene. Protein tyrosine phosphatase ( PTP), non-receptor type 5, also known as STEP (STriatal-Enriched protein tyrosine Phosphatase), was the first brain-specific PTP discovered. The human STEP locus maps to chromosome 11p15.2-p15.1 and the murine STEP gene to chromosome 7B3-B5. The single STEP gene is alternatively spliced to produce several isoforms, the best characterized of which are the cytosolic STEP46 protein and the membrane-associated STEP61 protein. Substrates Seven known targets of STEP have been identified as of 2015, including ERK1/2, p38, Fyn, Pyk2, PTPα, and the glutamate receptor subunits GluN2B and GluA2. STEP dephosphorylation of the kinases (ERK1/2, p38, Fyn, and Pyk2) occurs at a regulatory tyrosine within the kinase activation loop and leads to their inactivation. Dephosphorylation of a regulatory tyrosine on PTPα prevents the translocation of PTPα ...
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