St James's University Hospital, Leeds
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St James's University Hospital, Leeds
St James's University Hospital ''Confirming name as "St James's"'' is in Leeds, West Yorkshire, England and is popularly known as Jimmy's. It is one of the United Kingdom's most famous hospitals due to its coverage on television. It is managed by the Leeds Teaching Hospitals NHS Trust. History The hospital has its origins in the Leeds Moral and Industrial Training School built in 1848 (which now forms part of the Lincoln Wing). Subsequent early developments included the Leeds Union Workhouse (which now houses the Thackray Medical Museum) built in 1858. The chapel, which is a Grade II listed building, was completed in 1861 by the firm of Perkin & Beckhouse, of Leeds, and the Leeds Union Infirmary (the site of the present Gledhow Wing) was built in 1874.P. M Pennock ''Publications of the Thoresby Society'', Vol LIX part 2, no 130, pp. 124–76 "The Evolution of St James's 1848–97" By the end of the 19th century, the facilities were largely used for medical care of the poor, ...
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Leeds
Leeds () is a city and the administrative centre of the City of Leeds district in West Yorkshire, England. It is built around the River Aire and is in the eastern foothills of the Pennines. It is also the third-largest settlement (by population) in England, after London and Birmingham. The city was a small manorial borough in the 13th century and a market town in the 16th century. It expanded by becoming a major production centre, including of carbonated water where it was invented in the 1760s, and trading centre (mainly with wool) for the 17th and 18th centuries. It was a major mill town during the Industrial Revolution. It was also known for its flax industry, iron foundries, engineering and printing, as well as shopping, with several surviving Victorian era arcades, such as Kirkgate Market. City status was awarded in 1893, a populous urban centre formed in the following century which absorbed surrounding villages and overtook the nearby York population. It is locate ...
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Leeds General Infirmary
Leeds General Infirmary, also known as the LGI, is a large teaching hospital based in the centre of Leeds, West Yorkshire, England, and is part of the Leeds Teaching Hospitals NHS Trust. Its previous name The General Infirmary at Leeds is still sometimes used. The LGI is a specialist centre for a number of services, including the Major Trauma Centre and hand transplants. It also provides many general acute services like A&E, intensive care and high dependency units, maternity and state-of-the-art operating theatres. Two new hospitals are planned on the site. One will be a maternity unit with capacity to deliver up to 10,500 babies a year. Completion is planned between 2026-2028. It will remove the need to transfer expectant mothers between St James’s Hospital and Leeds General Infirmary. History The first hospital known as Leeds Infirmary was opened in 1771 on what is now the site of the former Yorkshire Bank in Infirmary Street off City Square, Leeds. Notably, the found ...
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Wellcome Trust
The Wellcome Trust is a charitable foundation focused on health research based in London, in the United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of one of the predecessors of GlaxoSmithKline) to fund research to improve human and animal health. The aim of the Trust is to "support science to solve the urgent health challenges facing everyone." It had a financial endowment of Pound sterling, £29.1 billion in 2020, making it the fourth List of wealthiest charitable foundations, wealthiest charitable foundation in the world. In 2012, the Wellcome Trust was described by the ''Financial Times'' as the United Kingdom's largest provider of non-governmental funding for scientific research, and one of the largest providers in the world. According to their annual report, the Wellcome Trust spent GBP Pound sterling, £1.1Bn on charitable activities across their 2019/2020 financial year. According to the OECD, the Wellcome ...
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Oncology
Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is concerned with: * The diagnosis of any cancer in a person (pathology) * Therapy (e.g. surgery, chemotherapy, radiotherapy and other modalities) * Follow-up of cancer patients after successful treatment * Palliative care of patients with terminal malignancies * Ethical questions surrounding cancer care * Screening efforts: ** of populations, or ** of the relatives of patients (in types of cancer that are thought to have a hereditary basis, such as breast cancer) Diagnosis Medical histories remain an important screening tool: the character of the complaints and nonspecific symptoms (such as fatigue, weight loss, unexplained anemia, fever of unknown origin, paraneoplastic phenome ...
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ITV (TV Network)
ITV is a British free-to-air public broadcast television network. It was launched in 1955 as Independent Television to provide competition to BBC Television (established in 1936). ITV is the oldest commercial network in the UK. Since the passing of the Broadcasting Act 1990, it has been legally known as Channel 3 to distinguish it from the other analogue channels at the time, BBC1, BBC2 and Channel 4. ITV was for four decades a network of separate companies which provided regional television services and also shared programmes between each other to be shown on the entire network. Each franchise was originally owned by a different company. After several mergers, the fifteen regional franchises are now held by two companies: ITV plc, which runs the ITV1 channel, and STV Group, which runs the STV channel. The ITV network is a separate entity from ITV plc, the company that resulted from the merger of Granada plc and Carlton Communications in 2004. ITV plc holds the Channel 3 ...
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Yorkshire Television
ITV Yorkshire, previously known as Yorkshire Television and commonly referred to as just YTV, is the British television service provided by ITV Broadcasting Limited for the Yorkshire franchise area on the ITV (TV network), ITV network. Until 1974, this was primarily the historic county of Yorkshire and parts of neighbouring counties served by the Emley Moor transmitting station, Emley Moor transmitter. Following a reorganisation in 1974 the transmission area was extended to include Lincolnshire, northwestern Norfolk and parts of Derbyshire and Nottinghamshire, served by the Belmont transmitting station, Belmont transmitter. Two consortia applied for the franchise, ''Telefusion Yorkshire Ltd'' and ''Yorkshire Independent Television'', the former having large financial backing (supported by the Blackpool-based ''Telefusion'' television rental chain) and the latter having the better plans but fewer resources. On 1 January 2007, the company transferred its programme production bus ...
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Listed Building
In the United Kingdom, a listed building or listed structure is one that has been placed on one of the four statutory lists maintained by Historic England in England, Historic Environment Scotland in Scotland, in Wales, and the Northern Ireland Environment Agency in Northern Ireland. The term has also been used in the Republic of Ireland, where buildings are protected under the Planning and Development Act 2000. The statutory term in Ireland is " protected structure". A listed building may not be demolished, extended, or altered without special permission from the local planning authority, which typically consults the relevant central government agency, particularly for significant alterations to the more notable listed buildings. In England and Wales, a national amenity society must be notified of any work to a listed building which involves any element of demolition. Exemption from secular listed building control is provided for some buildings in current use for worship, ...
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Cystic Fibrosis
Cystic fibrosis (CF) is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms. Cystic fibrosis is inherited in an autosomal recessive manner. It is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Those with a single working copy are carriers and otherwise mostly healthy. CFTR is involved in the production of sweat, digestive fluids, and mucus. When the CFTR is not functional, secretions which are usually thin instead become thick. The condition is diagnosed by a sweat test and genetic testing. Screening of infants at bi ...
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Liver Transplantation
Liver transplantation or hepatic transplantation is the replacement of a diseased liver with the healthy liver from another person (allograft). Liver transplantation is a treatment option for end-stage liver disease and acute liver failure, although availability of donor organs is a major limitation. The most common technique is orthotopic transplantation, in which the native liver is removed and replaced by the donor organ in the same anatomic position as the original liver. The surgical procedure is complex, requiring careful harvest of the donor organ and meticulous implantation into the recipient. Liver transplantation is highly regulated, and only performed at designated transplant medical centers by highly trained transplant physicians and supporting medical team. The duration of the surgery ranges from 4 to 18 hours depending on outcome. Favorable outcomes require careful screening for eligible recipient, as well as a well-calibrated live or cadaveric donor match. Medic ...
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Harehills
Harehills is an inner-city area of east Leeds, West Yorkshire, England. It is approximately north east of Leeds city centre. Harehills is situated between the A58 (towards Wetherby) and the A64 (towards York). It sits in the Gipton & Harehills ward of Leeds City Council and the Leeds East parliamentary constituency, between Burmantofts and Gipton, and adjacent to Chapeltown. Its boundaries are defined by the city council as "the boundary of Spencer Place to the West, Harehills Avenue to the North, the boundary of Foundry Place to the East and Compton Road and Stanley Road to the South." As the name suggests, it is a hill area, basically a south-facing slope, with many streets of terraced houses on hills. In the middle is Banstead Park, a grassy slope with trees and play areas, giving a view over the city of Leeds. There are two main shopping streets, Harehills Lane and Harehills Road which join at the junction of Roundhay Road ( A58 road) leading to Oakwood. Also, he ...
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Court Of Appeal Of England And Wales
The Court of Appeal (formally "His Majesty's Court of Appeal in England", commonly cited as "CA", "EWCA" or "CoA") is the highest court within the Courts of England and Wales#Senior Courts of England and Wales, Senior Courts of England and Wales, and second in the legal system of England and Wales only to the Supreme Court of the United Kingdom. The Court of Appeal was created in 1875, and today comprises 39 Lord Justices of Appeal and Lady Justices of Appeal. The court has two divisions, Criminal and Civil, led by the Lord Chief Justice of England and Wales, Lord Chief Justice and the Master of the Rolls, Master of the Rolls and Records of the Chancery of England respectively. Criminal appeals are heard in the Criminal Division, and civil appeals in the Civil Division. The Criminal Division hears appeals from the Crown Court, while the Civil Division hears appeals from the County Court (England and Wales), County Court, High Court of Justice and Family Court (England and Wales ...
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Insulin
Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the ''INS'' gene. It is considered to be the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of glucose from the blood into liver, fat and skeletal muscle cells. In these tissues the absorbed glucose is converted into either glycogen via glycogenesis or fats (triglycerides) via lipogenesis, or, in the case of the liver, into both. Glucose production and secretion by the liver is strongly inhibited by high concentrations of insulin in the blood. Circulating insulin also affects the synthesis of proteins in a wide variety of tissues. It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into large molecules inside the cells. Low insulin levels in the blood have the opposite effect by promoting widespread catabolism, especially o ...
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