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Sporozoa
The Apicomplexa (also called Apicomplexia) are a large phylum of parasitic alveolates. Most of them possess a unique form of organelle that comprises a type of non-photosynthetic plastid called an apicoplast, and an apical complex structure. The organelle is an adaptation that the apicomplexan applies in penetration of a host cell. The Apicomplexa are unicellular and spore-forming. All species are obligate endoparasites of animals, except '' Nephromyces'', a symbiont in marine animals, originally classified as a chytrid fungus. Motile structures such as flagella or pseudopods are present only in certain gamete stages. The Apicomplexa are a diverse group that includes organisms such as the coccidia, gregarines, piroplasms, haemogregarines, and plasmodia. Diseases caused by Apicomplexa include: * Babesiosis ('' Babesia'') * Malaria (''Plasmodium'') * Cryptosporidiosis (''Cryptosporidium parvum'') * Cyclosporiasis ('' Cyclospora cayetanensis'') * Cystoisosporiasis ('' Cystoi ...
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Coccidia
Coccidia (Coccidiasina) are a subclass of microscopic, spore-forming, single-celled obligate intracellular parasites belonging to the apicomplexan class Conoidasida. As obligate intracellular parasites, they must live and reproduce within an animal cell. Coccidian parasites infect the intestinal tracts of animals, and are the largest group of apicomplexan protozoa. Infection with these parasites is known as coccidiosis. Coccidia can infect all mammals, some birds, some fish, some reptiles, and some amphibians. Most species of coccidia are species-specific in their host. An exception is ''Toxoplasma gondii'', which can infect all mammals, although it can only undergo sexual reproduction in cats. Depending on the species of coccidia, infection can cause fever, vomiting, diarrhea, muscle pain, and nervous system effects and changes to behavior, and may lead to death. Healthy adults may recover without medication—but those who are immunocompromised or young almost certainly re ...
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Coccidiasina
Coccidia (Coccidiasina) are a subclass of microscopic, spore-forming, single-celled obligate intracellular parasites belonging to the apicomplexan class Conoidasida. As obligate intracellular parasites, they must live and reproduce within an animal cell. Coccidian parasites infect the intestinal tracts of animals, and are the largest group of apicomplexan protozoa. Infection with these parasites is known as coccidiosis. Coccidia can infect all mammals, some birds, some fish, some reptiles, and some amphibians. Most species of coccidia are species-specific in their host. An exception is ''Toxoplasma gondii'', which can infect all mammals, although it can only undergo sexual reproduction in cats. Depending on the species of coccidia, infection can cause fever, vomiting, diarrhea, muscle pain, and nervous system effects and changes to behavior, and may lead to death. Healthy adults may recover without medication—but those who are immunocompromised or young almost certainly requi ...
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Piroplasm
Piroplasmida is an order of parasites in the phylum Apicomplexa. They divide by binary fission and as sporozoan parasites they possess sexual and asexual phases (sexual reproduction occurs in the tick gut). They include the tick parasites '' Babesia'' and ''Theileria''. Description They are minute rounded or pyriform parasites found within erythrocytes, or other circulating or endothelial cells of vertebrates, where they reproduce by merogony. The trophozoite stage is separated from erythrocyte by a single membrane. This distinguishes them from other blood parasites that usually have at least two membranes. An apical complex with a polar ring and rhopteries occurs, but without a conoid and usually without associated pellicular microtubules. They lack flagella and do not form either oocysts or spores. The known vectors are ticks or leeches in which they undergo sporogony; sexual reproduction probably occurs in the vector. See also * Babesiosis Babesiosis or piro ...
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Coccidia
Coccidia (Coccidiasina) are a subclass of microscopic, spore-forming, single-celled obligate intracellular parasites belonging to the apicomplexan class Conoidasida. As obligate intracellular parasites, they must live and reproduce within an animal cell. Coccidian parasites infect the intestinal tracts of animals, and are the largest group of apicomplexan protozoa. Infection with these parasites is known as coccidiosis. Coccidia can infect all mammals, some birds, some fish, some reptiles, and some amphibians. Most species of coccidia are species-specific in their host. An exception is ''Toxoplasma gondii'', which can infect all mammals, although it can only undergo sexual reproduction in cats. Depending on the species of coccidia, infection can cause fever, vomiting, diarrhea, muscle pain, and nervous system effects and changes to behavior, and may lead to death. Healthy adults may recover without medication—but those who are immunocompromised or young almost certainly re ...
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Aconoidasida
The Aconoidasida are a class of apicomplexan parasites created by Mehlhorn ''et al'' in 1980. Description Organisms in this class bear a tip at one end of their outer membrane. This apical complex includes vesicles called rhoptries and micronemes, which open at the anterior of the cell. These secrete enzymes that allow the parasite to enter other cells. The tip is surrounded by a band of microtubule Microtubules are polymers of tubulin that form part of the cytoskeleton and provide structure and shape to eukaryotic cells. Microtubules can be as long as 50 micrometres, as wide as 23 to 27  nm and have an inner diameter between 11 an ...s, called the polar ring. As the name indicates, Aconoidasida (from Greek: negative prefix ''a-'' = "lacking") lack a conoid (they do have one only during the ookinete stage) in contrast to the class Conoidasida which have one throughout their life cycle. See also * Haemosporidiasina References Alveolata classes ...
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Pseudopod
A pseudopod or pseudopodium (plural: pseudopods or pseudopodia) is a temporary arm-like projection of a eukaryotic cell membrane that is emerged in the direction of movement. Filled with cytoplasm, pseudopodia primarily consist of actin filaments and may also contain microtubules and intermediate filaments. Pseudopods are used for motility and ingestion. They are often found in amoebas. Different types of pseudopodia can be classified by their distinct appearances. Lamellipodia are broad and thin. Filopodia are slender, thread-like, and are supported largely by microfilaments. Lobopodia are bulbous and amoebic. Reticulopodia are complex structures bearing individual pseudopodia which form irregular nets. Axopodia are the phagocytosis type with long, thin pseudopods supported by complex microtubule arrays enveloped with cytoplasm; they respond rapidly to physical contact. Some pseudopodial cells are able to use multiple types of pseudopodia depending on the situation: Most of ...
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Cryptosporidium Parvum
''Cryptosporidium parvum'' is one of several species that cause cryptosporidiosis, a parasitic disease of the mammalian intestinal tract. Primary symptoms of ''C. parvum'' infection are acute, watery, and nonbloody diarrhea. ''C. parvum'' infection is of particular concern in immunocompromised patients, where diarrhea can reach 10–15 times per day. Other symptoms may include anorexia, nausea/vomiting, and abdominal pain. Extra-intestinal sites include the lung, liver, and gall bladder, where it causes respiratory cryptosporidiosis, hepatitis, and cholecystitis, respectively. Infection is caused by ingestion of sporulated oocysts transmitted by the faecal-oral route. In healthy human hosts, the median infective dose is 132 oocysts. The general ''C. parvum'' lifecycle is shared by other members of the genus. Invasion of the apical tip of ileal enterocytes by sporozoites and merozoites causes pathology seen in the disease. Infection is generally self-limiting in immu ...
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Cryptosporidiosis
Cryptosporidiosis, sometimes informally called crypto, is a parasitic disease caused by '' Cryptosporidium'', a genus of protozoan parasites in the phylum Apicomplexa. It affects the distal small intestine and can affect the respiratory tract in both immunocompetent (i.e., individuals with a normal functioning immune system) and immunocompromised (e.g., persons with HIV/AIDS or autoimmune disorders) individuals, resulting in watery diarrhea with or without an unexplained cough. In immunosuppressed individuals, the symptoms are particularly severe and can be fatal. It is primarily spread through the fecal-oral route, often through contaminated water; recent evidence suggests that it can also be transmitted via fomites contaminated with respiratory secretions. ''Cryptosporidium'' is commonly isolated in HIV-positive patients presenting with diarrhea. Despite not being identified until 1976, it is one of the most common waterborne diseases and is found worldwide. The infection ...
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Plasmodium
''Plasmodium'' is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects. The life cycles of ''Plasmodium'' species involve development in a blood-feeding insect host which then injects parasites into a vertebrate host during a blood meal. Parasites grow within a vertebrate body tissue (often the liver) before entering the bloodstream to infect red blood cells. The ensuing destruction of host red blood cells can result in malaria. During this infection, some parasites are picked up by a blood-feeding insect ( mosquitoes in majority cases), continuing the life cycle. ''Plasmodium'' is a member of the phylum Apicomplexa, a large group of parasitic eukaryotes. Within Apicomplexa, ''Plasmodium'' is in the order Haemosporida and family Plasmodiidae. Over 200 species of ''Plasmodium'' have been described, many of which have been subdivided into 14 subgenera based on parasite morphology and host range. Evolutionary relationships among different ' ...
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Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the '' Plasmodium'' group. It is spread exclusively through bites of infected '' Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spr ...
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Babesia
''Babesia'', also called ''Nuttallia'', is an apicomplexan parasite that infects red blood cells and is transmitted by ticks. Originally discovered by the Romanian bacteriologist Victor Babeș in 1888, over 100 species of ''Babesia'' have since been identified. ''Babesia'' comprises more than 100 species of tick-borne parasites that infect erythrocytes (red blood cells) in many vertebrate hosts. ''Babesia'' species infect livestock worldwide, wild and domestic vertebrate animals, and occasionally humans, where they cause the disease babesiosis. In the United States, ''B. microti'' is the most common strain of the few which have been documented to cause disease in humans. Classification ''Babesia'' is a protozoan parasite found to infect vertebrate animals, mostly livestock mammals and birds, but also occasionally humans. Common names of the disease that ''Babesia microti'' causes are Texas cattle fever, redwater fever, tick fever, and Nantucket fever. The disease it cause ...
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Babesiosis
Babesiosis or piroplasmosis is a malaria-like parasitic disease caused by infection with a eukaryotic parasite in the order Piroplasmida, typically a '' Babesia'' or ''Theileria'', in the phylum Apicomplexa. Human babesiosis transmission via tick bite is most common in the Northeastern and Midwestern United States and parts of Europe, and sporadic throughout the rest of the world. It occurs in warm weather. People can get infected with ''Babesia'' parasites by the bite of an infected tick, by getting a blood transfusion from an infected donor of blood products, or by congenital transmission (an infected mother to her baby). Ticks transmit the human strain of babesiosis, so it often presents with other tick-borne illnesses such as Lyme disease. After trypanosomes, ''Babesia'' is thought to be the second-most common blood parasite of mammals. They can have major adverse effects on the health of domestic animals in areas without severe winters. In cattle the disease is known ...
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