Splice (2009 Film)
''Splice'' is a 2009 science fiction horror film directed by Vincenzo Natali and starring Adrien Brody, Sarah Polley, and Delphine Chanéac. The story concerns experiments in genetic engineering being done by a young scientific couple, who attempt to introduce human DNA into their work of splicing animal genes. Guillermo del Toro, Don Murphy, and Joel Silver are the executive producers of this film. Theatrically released on June 4, 2010, the film received generally positive reviews from critics but grossed just $27 million against a $30 million production budget. Plot Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by splicing animal DNA to create hybrids for medical use at the company N.E.R.D. (Nucleic Exchange Research and Development). Their work has yielded Fred and Ginger, two large vermiform creatures intended as mates for each other. After successfully mating them, Clive and Elsa plan to create a revolutionary human-animal hybrid. Their employers Joa ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Vincenzo Natali
Vincenzo Natali (born 1969) is an American-born Canadian film director and screenwriter, known for writing and directing Science fiction film, science fiction and horror films such as ''Cube (1997 film), Cube'', ''Cypher (film), Cypher'', ''Nothing (film), Nothing'', and ''Splice (film), Splice''. Early life and education Natali was born in Detroit, to a nursery school teacher/painter mother and a photographer father. He is of Italian and English descent. He moved to Toronto, along with his family, at the age of one. During his time at Royal St. George's College, Natali befriended British-born Canadian actor David Hewlett, who has appeared in the majority of films that Natali has directed. Natali also attended the film programme at Ryerson Polytechnical Institute. He was eventually hired as a storyboard artist at the Nelvana Animation Studios. His cinematic influences included Samuel Beckett, David Cronenberg, and Terry Gilliam. Career Natali's directing debut came in 1997, when ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Guillermo Del Toro
Guillermo del Toro Gómez (; born October 9, 1964) is a Mexican filmmaker, author, and actor. He directed the Academy Award–winning fantasy films ''Pan's Labyrinth'' (2006) and ''The Shape of Water'' (2017), winning the Academy Awards for Best Director and Best Picture for the latter. Throughout his career, del Toro has shifted between Spanish-language films—such as '' Cronos'' (1993), ''The Devil's Backbone'' (2001), and ''Pan's Labyrinth—''and English-language films, including ''Mimic'' (1997), ''Blade II'' (2002), ''Hellboy'' (2004), '' Hellboy II: The Golden Army'' (2008), ''Pacific Rim'' (2013), ''Crimson Peak'' (2015), ''The Shape of Water'' (which he later novelized), '' Nightmare Alley'' (2021), and the stop-motion animated film ''Pinocchio'' (2022). As a producer or writer, he worked on the films '' The Orphanage'' (2007), '' Don't Be Afraid of the Dark'' (2010), ''The Hobbit'' film series (2012–2014), ''Mama'' (2013), '' The Book of Life'' (2014), '' Pacific ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
David Hewlett
David Ian Hewlett (born 18 April 1968) is a British-born Canadian actor, writer, and director known for his role as Dr. Rodney McKay in the '' Stargate'' science-fiction franchise. He first gained fame for his roles as Grant Jansky in the Canadian TV series '' Traders'' (1996—2000) and as David Worth in the Canadian psychological horror film ''Cube'' (1997). He had earlier appeared in the horror film ''Pin'' (1988) and the science-fiction film '' Scanners II: The New Order'' (1991). More recently, Hewlett had a prominent supporting role in ''Rise of the Planet of the Apes'' (2011), portraying bad-tempered airplane pilot Douglas Hunsiker opposite John Lithgow and Andy Serkis. Hewlett played the character Fleming in the multi-Academy Award winning film ''The Shape of Water'' (2017). Early life Hewlett was born in Redhill, England, and moved with his family to Canada at the age of four. Hewlett received his first computer in his mid-teens and became a self-described "comput ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Patents
A patent is a type of intellectual property that gives its owner the legal right to exclude others from making, using, or selling an invention for a limited period of time in exchange for publishing an enabling disclosure of the invention."A patent is not the grant of a right to make or use or sell. It does not, directly or indirectly, imply any such right. It grants only the right to exclude others. The supposition that a right to make is created by the patent grant is obviously inconsistent with the established distinctions between generic and specific patents, and with the well-known fact that a very considerable portion of the patents granted are in a field covered by a former relatively generic or basic patent, are tributary to such earlier patent, and cannot be practiced unless by license thereunder." – ''Herman v. Youngstown Car Mfg. Co.'', 191 F. 579, 584–85, 112 CCA 185 (6th Cir. 1911) In most countries, patent rights fall under private law and the patent holder mus ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Carnivorous
A carnivore , or meat-eater (Latin, ''caro'', genitive ''carnis'', meaning meat or "flesh" and ''vorare'' meaning "to devour"), is an animal or plant whose food and energy requirements derive from animal tissues (mainly muscle, fat and other soft tissues) whether through hunting or scavenging. Nomenclature Mammal order The technical term for mammals in the order Carnivora is ''carnivoran'', and they are so-named because most member species in the group have a carnivorous diet, but the similarity of the name of the order and the name of the diet causes confusion. Many but not all carnivorans are meat eaters; a few, such as the large and small cats (felidae) are ''obligate'' carnivores (see below). Other classes of carnivore are highly variable. The Ursids, for example: While the Arctic polar bear eats meat almost exclusively (more than 90% of its diet is meat), almost all other bear species are omnivorous, and one species, the giant panda, is nearly exclusively herbivorous. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Sequential Hermaphroditism
Sequential hermaphroditism (called dichogamy in botany) is a type of hermaphroditism that occurs in many fish, gastropods, and plants. Sequential hermaphroditism occurs when the individual changes its sex at some point in its life. In particular, a sequential hermaphrodite produces eggs (female gametes) and sperm (male gametes) at different stages in life. Species that can undergo these changes from one sex to another do so as a normal event within their reproductive cycle that is usually cued by either social structure or the achievement of a certain age or size. In animals, the different types of change are male to female (protandry or protandrous hermaphroditism), female to male (protogyny or protogynous hermaphroditism), bidirectional (serial or bidirectional hermaphroditism). Both protogynous and protandrous hermaphroditism allow the organism to switch between functional male and functional female. Bidirectional hermaphrodites have the capacity for sex change in either directi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Nurturant Parent Model
The nurturant parent model also "Nurturing Parent" is a metaphor, for a belief system, which is built upon an underlying value system. In this Nurturant Parenting contrasts with Stern Father parenting (Strict Father) as two distinct metaphors each used as icons of contrasting value and political systems, i.e. conservative (Strict Father) and liberal (Nurturing Parent). The Nurturant Parent metaphor draws on parenting style. The ideal, effective Nurturing Parent gives his children both "roots in the ground and wings to fly." He or she does this by imparting, conveying, role-modeling and enforcing boundaries which encourage the child towards personal freedom (try out your new wings). The Nurturant Parent model has a healthy respect for children's inherent intelligence. As safe and appropriate, they can and should be allowed to explore their environment. Parents are responsible for protecting their child from serious mistakes, by offering guidance. A child will be picked up if t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Amphibious
Amphibious means able to use either land or water. In particular it may refer to: Animals * Amphibian, a vertebrate animal of the class Amphibia (many of which live on land and breed in water) * Amphibious caterpillar * Amphibious fish, a fish that is able to leave water for extended periods of time * Amphibious insect, an insect which lives in the air or on land and breeds in water * Amphibious rat (other) * ''Scolopendra cataracta'', a species of amphibious centipede Arts and media * ''Amphibious'' (2010 film), a thriller film * ''Amphibious'' (2020 film), a drama film * Amphibius (comics), a minor comic book character Technology * Amphibious aircraft, an aircraft capable of landing on either water or land * Amphibious vehicle, a vehicle capable of being driven on both land and water * Amphibious warfare Amphibious warfare is a type of offensive military operation that today uses naval ships to project ground and air power onto a hostile or potentially host ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Prepubescent
Preadolescence is a stage of human development following middle childhood and preceding adolescence.New Oxford American Dictionary. 2nd Edition. 2005. Oxford University Press. It commonly ends with the beginning of puberty. Preadolescence is commonly defined as ages 9–12 ending with the major onset of puberty. It may also be defined as simply the 2-year period before the major onset of puberty. Preadolescence can bring its own challenges and anxieties. Terminology A term used to refer to the preadolescent stage in everyday speech is tween and its perhaps older variants tweenie, tweeny, tweenager, and tweener. It's a blend (portmanteau) of the words "teen" and "between" in the sense of "between childhood and adolescence" and refers to 8-, 9-, or 10- to 12-year-olds. Sometimes the terms ''tweenie'' and ''tweenager'' are used to differentiate between older (10 to 15) and younger (7 to 11) age groups, respectively. While known as ''preadolescent'' in psychology, the terms ''pre ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Viability Selection
Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the heritable traits characteristic of a population over generations. Charles Darwin popularised the term "natural selection", contrasting it with artificial selection, which in his view is intentional, whereas natural selection is not. Variation exists within all populations of organisms. This occurs partly because random mutations arise in the genome of an individual organism, and their offspring can inherit such mutations. Throughout the lives of the individuals, their genomes interact with their environments to cause variations in traits. The environment of a genome includes the molecular biology in the cell, other cells, other individuals, populations, species, as well as the abiotic environment. Because individuals with certain variants of the trait tend to survive and reproduce more than individuals with o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Vermiform
Vermiform (ˈvərməˌfôrm) describes something shaped like a worm. The expression is often employed in biology and anatomy to describe usually soft body parts or animals that are more or less tubular or cylindrical. The word root is Latin, ''vermes'' (worms) and ''formes'' (shaped). A well known example is the vermiform appendix, a small, blind section of the gut in humans and a number of other mammals. A number of soft-bodied animal phyla are typically described as vermiform. The better-known ones are undoubtedly the annelids (earthworm and relatives) and the roundworms (a very common, mainly parasitic group), but a number of less-well-known phyla answer to the same description. Examples range from the minute parasitic mesozoans to the larger-bodied free-living phyla like ribbon worms, peanut worms, and priapulids Priapulida (priapulid worms, from Gr. πριάπος, ''priāpos'' ' Priapus' + Lat. ''-ul-'', diminutive), sometimes referred to as penis worms, is a phylum o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |