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Spirocerca Lupi
Epidemiology ''S. lupi'' is endemic (occurs naturally) from southern Africa all the way up to Israel, Turkey, Greece and India; faecal evidence also exists for it in the southern USA. Although early reports of the disease were American 1-3, few reports emerge any longer from this country. This may be because a commonly-used insecticide wiped out a lot of the hosts, before being banned – so never reached Israel or SA (anecdotal). This parasite has a complex 110-day life cycle with both intermediate and paratenic (=transport) hosts. Coprophagous (“dung”) beetles are the intermediate hosts, ingesting the eggs which contain the L1 larvae. Within this host, the eggs encysts and develop into the infectious L3 larvae in 2 months. The infectious process can be direct (ingestion of an infected beetle) or indirect (ingestion by a paratenic host such as wild birds and poultry, lizards and rodents, rabbits ...
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Animal
Animals are multicellular, eukaryotic organisms in the Kingdom (biology), biological kingdom Animalia. With few exceptions, animals Heterotroph, consume organic material, Cellular respiration#Aerobic respiration, breathe oxygen, are Motility, able to move, can Sexual reproduction, reproduce sexually, and go through an ontogenetic stage in which their body consists of a hollow sphere of Cell (biology), cells, the blastula, during Embryogenesis, embryonic development. Over 1.5 million Extant taxon, living animal species have been Species description, described—of which around 1 million are Insecta, insects—but it has been estimated there are over 7 million animal species in total. Animals range in length from to . They have Ecology, complex interactions with each other and their environments, forming intricate food webs. The scientific study of animals is known as zoology. Most living animal species are in Bilateria, a clade whose members have a Symmetry in biology#Bilate ...
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Nematoda
The nematodes ( or grc-gre, Νηματώδη; la, Nematoda) or roundworms constitute the phylum Nematoda (also called Nemathelminthes), with plant-parasitic nematodes also known as eelworms. They are a diverse animal phylum inhabiting a broad range of environments. Less formally, they are categorized as Helminths, but are taxonomically classified along with arthropods, tardigrades and other moulting animals in the clade Ecdysozoa, and unlike flatworms, have tubular digestive systems with openings at both ends. Like tardigrades, they have a reduced number of Hox genes, but their sister phylum Nematomorpha has kept the ancestral protostome Hox genotype, which shows that the reduction has occurred within the nematode phylum. Nematode species can be difficult to distinguish from one another. Consequently, estimates of the number of nematode species described to date vary by author and may change rapidly over time. A 2013 survey of animal biodiversity published in the mega jou ...
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Secernentea
Secernentea was a class of nematodes in the Classical Phylogeny System (Chitwood, 1958) and is no longer in use. This morphological-based classification system has been replaced by the Modern Phylogeny system, where taxonomy assignment is based on small subunit ribosomal DNA (SSU rDNA). Characteristics of Secernentea are: * Amphid apertures are pore/slit-like * Derids are present in some; located near nerve ring * Phasmids are present; posterior * Excretory system is tubular * Cuticle is striated in two to four layers; lateral field is present * Three esophageal glands; esophageal structure varies * Males generally have one testis * Caudal alae are common * Sensory papillae are cephalic only; may be caudal papillae in males * Mostly terrestrial * Rarely found in fresh or marine water Systematics Subclasses and orders of Secernentea are:Tree of Life Web Project (ToL) (2002)Nematoda. Version of January 1, 2002. Retrieved November 2, 2008. * Subclass Rhabditia (paraphyletic?) ...
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Spirurida
Spirurida is an order of spirurian nematodes. Like all nematodes, they have neither a circulatory nor a respiratory system. Some Spirurida, like the genus ''Gongylonema'', can cause disease in humans. One such disease is a skin infection with Spirurida larvae, called "creeping disease". Some species are known as eyeworms and infect the orbital cavity of animal hosts. Systematics The Camallanida are sometimes included herein as a suborder, and the Drilonematida are sometimes placed here as a superfamily. There are doubts about the internal systematics of the Spirurida, and some groups placed herein might belong to other spirurian or even secernentean lineages.ToL (2002) The following superfamilies are at least provisionally placed in the Spirurida: * Acuarioidea * Aproctoidea * Diplotriaenoidea * Filarioidea * Gnathostomatoidea * Habronematoidea * Physalopteroidea * Rictularioidea * Spiruroidea * Thelazioidea Thelazioidea is a superfamily of spirurian nematodes in th ...
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Spirocercidae
Spirocercidae is a family of nematodes belonging to the order Spirurida Spirurida is an order of spirurian nematodes. Like all nematodes, they have neither a circulatory nor a respiratory system. Some Spirurida, like the genus ''Gongylonema'', can cause disease in humans. One such disease is a skin infection with .... Genera Genera: * '' Ascarops'' van Beneden, 1873 * '' Cyathospirura'' Baylis, 1934 * '' Didelphonema'' Wolfgang, 1953 References {{Taxonbar, from=Q21293698 Nematodes ...
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Spirocerca
''Spirocerca'' is a genus of nematodes belonging to the family Spirocercidae. The genus has cosmopolitan distribution. Species: *'' Spirocerca arctica'' *''Spirocerca lupi Epidemiology ''S. lupi'' is endemic (occurs naturally) from southern Africa all the way up to Israel, Turkey, Greece and India; faecal evidence also exists for it in the southern USA. Although early reports of the disease were American 1-3, few ...'' References {{Taxonbar, from=Q18520309 Nematodes ...
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Moxidectin
Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms (helminths), such as heartworm and intestinal worms, in dogs, cats, horses, cattle and sheep. Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels. These channels are vital to the function of invertebrate nerve and muscle cells; when moxidectin binds to the channels, it disrupts neurotransmission, resulting in paralysis and death of the parasite. Medical uses Moxidectin was approved for onchocerciasis (river-blindness) in 2018 for people over the age of 11 in the United States based on two studies. There is a need for additional trials, with long-term follow-up, to assess whether moxidectin is safe and effective for treatment of nematode infection in children and women of childbearing potential. Moxidectin is predicted to be helpful to achieve elimination goals of this disease. * Dogs: Prevention ...
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Nematode
The nematodes ( or grc-gre, Νηματώδη; la, Nematoda) or roundworms constitute the phylum Nematoda (also called Nemathelminthes), with plant-Parasitism, parasitic nematodes also known as eelworms. They are a diverse animal phylum inhabiting a broad range of environments. Less formally, they are categorized as Helminths, but are taxonomically classified along with Arthropod, arthropods, Tardigrade, tardigrades and other moulting animalia, animals in the clade Ecdysozoa, and unlike platyhelminthe, flatworms, have tubular digestion, digestive systems with openings at both ends. Like tardigrades, they have a reduced number of Hox genes, but their sister phylum Nematomorpha has kept the ancestral protostome Hox genotype, which shows that the reduction has occurred within the nematode phylum. Nematode species can be difficult to distinguish from one another. Consequently, estimates of the number of nematode species described to date vary by author and may change rapidly over ...
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Esophagus
The esophagus (American English) or oesophagus (British English; both ), non-technically known also as the food pipe or gullet, is an organ in vertebrates through which food passes, aided by peristaltic contractions, from the pharynx to the stomach. The esophagus is a fibromuscular tube, about long in adults, that travels behind the trachea and heart, passes through the diaphragm, and empties into the uppermost region of the stomach. During swallowing, the epiglottis tilts backwards to prevent food from going down the larynx and lungs. The word ''oesophagus'' is from Ancient Greek οἰσοφάγος (oisophágos), from οἴσω (oísō), future form of φέρω (phérō, “I carry”) + ἔφαγον (éphagon, “I ate”). The wall of the esophagus from the lumen outwards consists of mucosa, submucosa (connective tissue), layers of muscle fibers between layers of fibrous tissue, and an outer layer of connective tissue. The mucosa is a stratified squamous epithel ...
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Doramectin
Doramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle. It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of ivermectin. Similarly to other drugs of this family, it is produced by fermentation by selected strains of ''Streptomyces avermitilis''. Its spectrum includes: ''Haemonchus, Ostertagia, Trichostrongylus, Cooperia'', and ''Oesophagostomum'' species and ''Dictyocaulus viviparus'', ''Dermatobia hominis, Boophilus microplus'', and ''Psoroptes bovis'', among many other internal and external parasites. It is available as an injection and as a 5-mg/ml topical solution. Doramectin is also marketed in many Latin-American and some Asia and Africa countries as Doramec L.A. (manufacture ...
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