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Simian Sarcoma Virus
Woolly monkey sarcoma virus (WMSV), with synonym Simian sarcoma virus (often abbreviated by SSV, but this may also stand for some species called ' Sulfolobus spindle-shaped virus', that belong to different genera in family Fuselloviridae) is a species of gammaretrovirus that infects primates. First isolation was from a fibrosarcoma in a woolly monkey The woolly monkeys are the genus ''Lagothrix'' of New World monkeys, usually placed in the family Atelidae. Both species in this genus originate from the rainforests of South America. They have prehensile tails and live in relatively large soci ... (genus ''Lagothrix''). For its reproduction the virus needs a helper or associated virus which is called Simian sarcoma associated virus (SSAV).Zoologix
Simian sarcoma virus (SSV) and simian sarcoma associated virus (SSAV)


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Sulfolobus Spindle-shaped Virus
''Sulfolobus'' is a genus of microorganism in the family Sulfolobaceae. It belongs to the archaea domain. ''Sulfolobus'' species grow in volcanic springs with optimal growth occurring at pH 2-3 and temperatures of 75-80 °C, making them acidophiles and thermophiles respectively. ''Sulfolobus'' cells are irregularly shaped and flagellar. Species of ''Sulfolobus'' are generally named after the location from which they were first isolated, e.g. ''Sulfolobus solfataricus'' was first isolated in the Solfatara volcano. Other species can be found throughout the world in areas of volcanic or geothermal activity, such as geological formations called mud pots, which are also known as ''solfatare'' (plural of solfatara). ''Sulfolobus'' as a model to study the molecular mechanisms of DNA replication When the first Archaeal genome, ''Methanococcus jannaschii'', had been sequenced completely in 1996, it was found that the genes in the genome of ''Methanococcus jannaschii'' involved i ...
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Fuselloviridae
''Fuselloviridae'' is a family of viruses. Sulfolobus species, specifically shibatae, solfataricus, and islandicus, serve as natural hosts. There are two genera and nine species in the family. The ''Fuselloviridae'' are ubiquitous in high-temperature (≥70 °C), acidic (pH ≤4) hot spring A hot spring, hydrothermal spring, or geothermal spring is a spring produced by the emergence of geothermally heated groundwater onto the surface of the Earth. The groundwater is heated either by shallow bodies of magma (molten rock) or by c ...s around the world. Taxonomy The family contains the following genera and species: * '' Alphafusellovirus'' ** '' Sulfolobus spindle-shaped virus 1'' ** '' Sulfolobus spindle-shaped virus 2'' ** '' Sulfolobus spindle-shaped virus 4'' ** '' Sulfolobus spindle-shaped virus 5'' ** '' Sulfolobus spindle-shaped virus 7'' ** '' Sulfolobus spindle-shaped virus 8'' ** '' Sulfolobus spindle-shaped virus 9'' * '' Betafusellovirus'' ** '' Acidianus s ...
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Gammaretrovirus
Gammaretrovirus is a genus in the ''Retroviridae'' Family (biology), family. Example species are the murine leukemia virus and the feline leukemia virus. They cause various sarcomas, leukemias and immune deficiencies in mammals, reptiles and birds. Introduction Many endogenous retroviruses, closely related to exogenous gammaretroviruses, are present in the DNA of mammals (including humans), birds, reptiles and amphibians. Many also share a conserved RNA structural element called a Gammaretrovirus core encapsidation signal, core encapsidation signal. The avian reticuloendotheliosis viruses are not strictly avian viruses—it appears that reticuloendotheliosis viruses are mammalian viruses that were accidentally introduced into birds in the 1930s during research on malaria. As a potential vector for gene therapy, gammaretroviruses have some advantages over Lentiviral vector in gene therapy#Use as a vector, HIV as a lentiviral vector. Specifically, the gammaretroviral packaging s ...
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Primates
Primates are a diverse order of mammals. They are divided into the strepsirrhines, which include the lemurs, galagos, and lorisids, and the haplorhines, which include the tarsiers and the simians (monkeys and apes, the latter including humans). Primates arose 85–55 million years ago first from small terrestrial mammals, which adapted to living in the trees of tropical forests: many primate characteristics represent adaptations to life in this challenging environment, including large brains, visual acuity, color vision, a shoulder girdle allowing a large degree of movement in the shoulder joint, and dextrous hands. Primates range in size from Madame Berthe's mouse lemur, which weighs , to the eastern gorilla, weighing over . There are 376–524 species of living primates, depending on which classification is used. New primate species continue to be discovered: over 25 species were described in the 2000s, 36 in the 2010s, and three in the 2020s. Primates have large bra ...
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Fibrosarcoma
Fibrosarcoma (fibroblastic sarcoma) is a malignant mesenchymal tumour derived from fibrous connective tissue and characterized by the presence of immature proliferating fibroblasts or undifferentiated anaplastic spindle cells in a storiform pattern. Fibrosarcomas mainly arise in people between the ages of 25–79 It originates in fibrous tissues of the bone and invades long or flat bones such as the femur, tibia, and mandible. It also involves the periosteum and overlying muscle. Presentation Adult-type Individuals presenting with fibrosarcoma are usually adults thirty to fifty-five years old, often presenting with pain. Among adults, fibrosarcomas develop equally in men and women. Infantile-type In infants, fibrosarcoma (often termed congenital infantile fibrosarcoma) is usually congenital. Infants presenting with this fibrosarcoma usually do so in the first two years of their life. Cytogenetically, congenital infantile fibrosarcoma is characterized by the majority of cases ...
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Woolly Monkey
The woolly monkeys are the genus ''Lagothrix'' of New World monkeys, usually placed in the family Atelidae. Both species in this genus originate from the rainforests of South America. They have prehensile tails and live in relatively large social groups. Taxonomy The following 2 species and 5 subspecies are currently considered to be within the genus: *Yellow-tailed woolly monkey, ''L. flavicauda'' (formerly placed in genus ''Oreonax'') * Common woolly monkey, ''L. lagothricha'' ** Gray woolly monkey, ''L. l. cana'' **Brown woolly monkey, ''L. l. lagothricha'' ** Colombian woolly monkey, ''L. l. lugens'' ** Silvery woolly monkey, ''L. l. poeppigii'' ** Peruvian woolly monkey, ''L. l. tschudii'' Description Woolly monkeys are closely related to spider monkeys. They have a thick brown coat with dark gray appendages. The stomach area is black and heads are light brown. The fur color is the same for both males and females. Variation in color exist among subspecies. A prehensile ...
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HL23V
HL23V was reputedly a type C RNA tumor virus first isolated in 1975 from cultured human acute myelogenous leukaemia peripheral blood leukocytes in the laboratory of Robert Gallo, which would have been the first cancer-causing retrovirus isolated from human sera. It was later shown to be a laboratory contaminant of three monkey viruses. The journal ''Nature'', which had published the original research, later retracted the article. Investigative journalist John Crewdson, writing in 2003, described how Gallo pretended mysterious laboratory accidents such as the unplugging of a laboratory freezer to excuse his failure to share samples of "HL23V" to researchers. As "HL23V" would have been the first human retrovirus discovered, bringing attention to Gallo and thus scientific prizes, observers noted that "23" was the number of Robert Gallo's birthday. Later in 1986, Max Essex of Harvard would announce the "discovery" of "HTLV-IV" in Senegalese women, supposedly a type C relative of HIV (th ...
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