Signaling Gateway (website)
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Signaling Gateway (website)
Signaling Gateway is a web portal dedicated to signaling pathways powered by the San Diego Supercomputer Center at the University of California, San Diego. It was initiated by a collaboration between the Alliance for Cellular Signaling and Nature Publishing Group, Nature. A primary feature is the Molecule Pages database. Molecule Pages Database (online database journal) Signaling Gateway Molecule Pages is a database containing "essential information on more than 8000 mammalian proteins (Mouse and Human) involved in cellular signaling." The content of molecule pages is authored by invited experts and is peer-reviewed. The published pages are citable by digital object identifiers (DOIs). All data in the Molecule Pages are freely available to the public. Data can be exported to PDF, XML, BioPAX/SBPAX and SBML. MIRIAM Registry Details. Some Published Molecule Pages * * * * References {{Reflist, 2 External links Signaling Gateway Molecule Pages
Cell biology Cell s ...
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Signaling Pathway
In biology, cell signaling (cell signalling in British English) is the process by which a cell interacts with itself, other cells, and the environment. Cell signaling is a fundamental property of all cellular life in both prokaryotes and eukaryotes. Typically, the signaling process involves three components: the signal, the receptor, and the effector. In biology, signals are mostly chemical in nature, but can also be physical cues such as pressure, voltage, temperature, or light. Chemical signals are molecules with the ability to bind and activate a specific receptor. These molecules, also referred to as ligands, are chemically diverse, including ions (e.g. Na+, K+, Ca2+, etc.), lipids (e.g. steroid, prostaglandin), peptides (e.g. insulin, ACTH), carbohydrates, glycosylated proteins (proteoglycans), nucleic acids, etc. Peptide and lipid ligands are particularly important, as most hormones belong to these classes of chemicals. Peptides are usually polar, hydrophilic molecules ...
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San Diego Supercomputer Center
The San Diego Supercomputer Center (SDSC) is an organized research unit of the University of California, San Diego. Founded in 1985, it was one of the five original NSF supercomputing centers. Its research pursuits are high performance computing, grid computing, computational biology, geoinformatics, computational physics, computational chemistry, data management, scientific visualization, cyberinfrastructure, and computer networking. SDSC computational biosciences contributions and earth science and genomics computational approaches are internationally recognized. The current SDSC director is Frank Würthwein, Ph.D., UC San Diego physics professor and a founding faculty member of the Halıcıoğlu Data Science Institute of UC San Diego. Würthwein assumed the role in July 2021. He succeeded Michael L. Norman, also a physics professor at UC San Diego, and who was the SDSC director since September 2010. Divisions and projects SDSC roles include creating and maintaining the Pro ...
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University Of California, San Diego
The University of California, San Diego (UC San Diego in communications material, formerly and colloquially UCSD) is a public university, public Land-grant university, land-grant research university in San Diego, California, United States. Established in 1960 near the pre-existing Scripps Institution of Oceanography in La Jolla, UC San Diego is the southernmost of the ten campuses of the University of California. It offers over 200 undergraduate and graduate degree programs, enrolling 33,096 undergraduate and 9,872 graduate students, with the second largest student housing capacity in the nation. The university occupies near the Pacific coast. UC San Diego consists of 12 undergraduate, graduate, and professional schools as well as 8 undergraduate residential colleges. The university operates 19 organized research units as well as 8 School of Medicine research units, 6 research centers at Scripps Institution of Oceanography, and 2 multi-campus initiatives. UC San Diego is als ...
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Nature Publishing Group
Nature Portfolio (formerly known as Nature Publishing Group and Nature Research) is a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines, online databases, and services in science and medicine. Nature Research's flagship publication is ''Nature'', a weekly multidisciplinary journal first published in 1869. It also publishes the ''Nature-''titled research journals, ''Nature Reviews'' journals (since 2000), society-owned academic journals, and a range of open access journals, including ''Scientific Reports'' and ''Nature Communications''. Springer Nature also publishes ''Scientific American'' in 16 languages, a magazine intended for the general public. In 2013, prior to the merger with Springer and the creation of Springer Nature, Nature Publishing Group's owner, Holtzbrinck Publishing Group, bought a controlling stake in Frontiers. Before Springer Nature was formed in 2015, Nature Research (as the Nature Publi ...
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