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Sidrón Cave
The Sidrón Cave ( ast, Cueva del Sidrón) is a non-carboniferous limestone karst cave system located in the Piloña municipality of Asturias, northwestern Spain, where Paleolithic rock art and the fossils of more than a dozen Neanderthals were found. Declared a ''"Partial Natural Reserve"'' in 1995, the site also serves as a retreat for five species of bats and is the place of discovery of two species of Coleoptera (beetles). Description The total length of this huge complex is approximately , which contains a central hall of length and the Neanderthal fossil site, called the ''Ossuary Gallery'', which is long and wide. In 1994, human remains were found accidentally in the cave. They were initially suspected to be from the Spanish Civil War because Republican fighters used to hide there; however, later analysis shows that the remains actually belong to Neanderthals. Galería del Osario The primary gallery of interest at the Sidron cave is the ''Ossuary Gallery'' or ''T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Piloña
Piloña () is a municipality in the province and autonomous community of Asturias, northwestern Spain. Its capital is the town of Infiesto. Piloña is bounded to the north by Villaviciosa and Colunga, to the east by Parres, to the west by Nava and Cabranes, and to the south by Ponga, Caso, Sobrescobio and Laviana. The area is semi-mountainous with many small, but deep and narrow valleys. History In prehistoric times there were paleolithic settlements in caves in Piloña such as Aviao (Espinaredo) Cave, Collaréu Cave, and La Peña Ferran (Ferran Rock) which were excavated by the Count de la Vega del Sella in the 1920s. There are several sites with paleolithic rock art and Neanderthal remains, including Sidrón Cave in Borines. Piloña lies in a narrow basin that runs parallel with the coast. Over time it formed part of the natural path between Oviedo and Cangas de Onís, which connects central Asturias with the Asturian east. Piloña was the largest settlement along tha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vertebral Column
The vertebral column, also known as the backbone or spine, is part of the axial skeleton. The vertebral column is the defining characteristic of a vertebrate in which the notochord (a flexible rod of uniform composition) found in all chordata, chordates has been replaced by a segmented series of bone: vertebrae separated by intervertebral discs. Individual vertebrae are named according to their region and position, and can be used as anatomical landmarks in order to guide procedures such as Lumbar puncture, lumbar punctures. The vertebral column houses the spinal canal, a cavity that encloses and protects the spinal cord. There are about 50,000 species of animals that have a vertebral column. The human vertebral column is one of the most-studied examples. Many different diseases in humans can affect the spine, with spina bifida and scoliosis being recognisable examples. The general structure of human vertebrae is fairly typical of that found in mammals, reptiles, and birds. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atapuerca Mountains
The Atapuerca Mountains ( es, Sierra de Atapuerca) is a karstic hill formation near the village of Atapuerca in the province of Burgos (autonomous community of Castile and Leon), northern Spain. In a still ongoing excavation campaign, rich fossil deposits and stone tool assemblages have been discovered which are attributed to the earliest known hominin residents in Western Europe. This "exceptional reserve of data" has been deposited during extensive Lower Paleolithic presence, as the Atapuerca Mountains served as the preferred occupation site of ''Homo erectus'', ''Homo antecessor'', ''Homo heidelbergensis'' and ''Homo neanderthalensis'' communities. The earliest specimen so far unearthed and reliably dated confirm an age between 1.2 million and 630,000 years. The Archaeological site of Atapuerca is a World Heritage Site. Some finds are exhibited in the nearby Museum of Human Evolution, in Burgos. Regional geography Encompassing , the Atapuerca Mountains are a mid-altitu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Fossil Sites
This list of fossil sites is a worldwide list of localities known well for the presence of fossils. Some entries in this list are notable for a single, unique find, while others are notable for the large number of fossils found there. Many of the entries in this list are considered Lagerstätten (sedimentary deposits that exhibits extraordinary fossils with exceptional preservation—sometimes including preserved soft tissues). Lagerstätten are indicated by a note () in the noteworthiness column. Fossils may be found either associated with a geological formation or at a single geographic site. Geological formations consist of rock that was deposited during a specific period of time. They usually extend for large areas, and sometimes there are different important sites in which the same formation is exposed. Such sites may have separate entries if they are considered to be more notable than the formation as a whole. In contrast, extensive formations associated with large areas m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The American Journal Of Human Genetics
The ''American Journal of Human Genetics'' is a monthly peer-reviewed scientific journal in the field of human genetics. It was established in 1948 by the American Society of Human Genetics and covers all aspects of heredity in humans, including the application of genetics in medicine and public policy, as well as the related areas of molecular and cell biology. According to the ''Journal Citation Reports'', the journal has a 2019 impact factor of 10.502. The journal is published by Cell Press an imprint of Elsevier. Bruce R. Korf became the editor-in-chief in the winter of 2017–2018. Past editors-in-chief * 1948–1951 — Charles W. Cotterham * 1952–1954 — Herluf H. Strandskov (1898–1984) * 1955— Laurence H. Snyder * 1956–1961 — Arthur G. Steinberg * 1962–1963 — C. Nash Herndon * 1964–1969 — H. Eldon Sutton * 1970–1975 — Arno Motulsky * 1976–1978 — William J. Mellman * 1979–1986 — David E. Comings * 1986–1993 — Charles J. Epstein * 1993– ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Minor Histocompatibility Antigen
Minor histocompatibility antigen (also known as MiHA) are receptors on the cellular surface of donated organs that are known to give an immunological response in some organ transplants. They cause problems of rejection less frequently than those of the major histocompatibility complex (MHC). Minor histocompatibility antigens (MiHAs) are diverse, short segments of proteins and are referred to as peptides . These peptides are normally around 9-12 amino acids in length and are bound to both the major histocompatibility complex (MHC) class I and class II proteins. Peptide sequences can differ among individuals and these differences arise from SNPs in the coding region of genes, gene deletions, frameshift mutations, or insertions. About a third of the characterized MiHAs come from the Y chromosome. The proteins are composed of a single immunogenic HLA allele . Prior to becoming a short peptide sequence, the proteins expressed by these polymorphic or diverse genes need to be digested ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Y Chromosome
The Y chromosome is one of two sex chromosomes (allosomes) in therian mammals, including humans, and many other animals. The other is the X chromosome. Y is normally the sex-determining chromosome in many species, since it is the presence or absence of Y that determines the male or female sex of offspring produced in sexual reproduction. In mammals, the Y chromosome contains the gene SRY, which triggers male development. The DNA in the human Y chromosome is composed of about 59 million base pairs, making it similar in size to chromosome 19. The Y chromosome is passed only from father to son. With a 30% difference between humans and chimpanzees, the Y chromosome is one of the fastest-evolving parts of the human genome. The human Y chromosome carries an estimated 100–200 genes, with between 45 and 73 of these being protein-coding. All single-copy Y-linked genes are hemizygous (present on only one chromosome) except in cases of aneuploidy such as XYY syndrome or XXYY syndrome. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FOXP2
Forkhead box protein P2 (FOXP2) is a protein that, in humans, is encoded by the ''FOXP2'' gene. FOXP2 is a member of the forkhead box family of transcription factors, proteins that regulate gene expression by binding to DNA. It is expressed in the brain, heart, lungs and digestive system. ''FOXP2'' is found in many vertebrates, where it plays an important role in mimicry in birds (such as birdsong) and echolocation in bats. ''FOXP2'' is also required for the proper development of speech and language in humans. In humans, mutations in ''FOXP2'' cause the severe speech and language disorder developmental verbal dyspraxia. Studies of the gene in mice and songbirds indicate that it is necessary for vocal imitation and the related motor learning. Outside the brain, ''FOXP2'' has also been implicated in development of other tissues such as the lung and digestive system. Initially identified in 1998 as the genetic cause of a speech disorder in a British family designated the KE fami ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Exon
An exon is any part of a gene that will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing. The term ''exon'' refers to both the DNA sequence within a gene and to the corresponding sequence in RNA transcripts. In RNA splicing, introns are removed and exons are covalently joined to one another as part of generating the mature RNA. Just as the entire set of genes for a species constitutes the genome, the entire set of exons constitutes the exome. History The term ''exon'' derives from the expressed region and was coined by American biochemist Walter Gilbert in 1978: "The notion of the cistron… must be replaced by that of a transcription unit containing regions which will be lost from the mature messengerwhich I suggest we call introns (for intragenic regions)alternating with regions which will be expressedexons." This definition was originally made for protein-coding transcripts that are spliced before being translated. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MtDNA
Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, such as adenosine triphosphate (ATP). Mitochondrial DNA is only a small portion of the DNA in a eukaryotic cell; most of the DNA can be found in the cell nucleus and, in plants and algae, also in plastids such as chloroplasts. Human mitochondrial DNA was the first significant part of the human genome to be sequenced. This sequencing revealed that the human mtDNA includes 16,569 base pairs and encodes 13 proteins. Since animal mtDNA evolves faster than nuclear genetic markers, it represents a mainstay of phylogenetics and evolutionary biology. It also permits an examination of the relatedness of populations, and so has become important in anthropology and biogeography. Origin Nuclear and mitochondrial DNA are thought to be of separate evolutionary origin, with the mtDNA being derived from t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atlas (anatomy)
In anatomy, the atlas (C1) is the most superior (first) cervical vertebra of the spine and is located in the neck. It is named for Atlas of Greek mythology because, just as Atlas supported the globe, it supports the entire head. The atlas is the topmost vertebra and, with the axis (the vertebra below it), forms the joint connecting the skull and spine. The atlas and axis are specialized to allow a greater range of motion than normal vertebrae. They are responsible for the nodding and rotation movements of the head. The atlanto-occipital joint allows the head to nod up and down on the vertebral column. The dens acts as a pivot that allows the atlas and attached head to rotate on the axis, side to side. The atlas's chief peculiarity is that it has no body. It is ring-like and consists of an anterior and a posterior arch and two lateral masses. The atlas and axis are important neurologically because the brainstem extends down to the axis. Structure Anterior arch The anterio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thoracic Vertebrae
In vertebrates, thoracic vertebrae compose the middle segment of the vertebral column, between the cervical vertebrae and the lumbar vertebrae. In humans, there are twelve thoracic vertebra (anatomy), vertebrae and they are intermediate in size between the cervical and lumbar vertebrae; they increase in size going towards the lumbar vertebrae, with the lower ones being much larger than the upper. They are distinguished by the presence of Zygapophysial joint, facets on the sides of the bodies for Articulation (anatomy), articulation with the head of rib, heads of the ribs, as well as facets on the transverse processes of all, except the eleventh and twelfth, for articulation with the tubercle (rib), tubercles of the ribs. By convention, the human thoracic vertebrae are numbered T1–T12, with the first one (T1) located closest to the skull and the others going down the spine toward the lumbar region. General characteristics These are the general characteristics of the second throu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
