Shoukhrat Mitalipov
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Shoukhrat Mitalipov
Shoukhrat Mitalipov (, russian: Шухрат Музапарович Миталипов; born 1961) is an American biologist who heads the Center for Embryonic Cell and Gene Therapy at the Oregon Health & Science University in Portland. He is a well known pioneer of many nuclear transplantation studies and was named in 2013 by journal ''Nature'' as "the cloning chief". Mitalipov is also a godfather of a gene therapy, known as mitochondrial replacement therapy, that prevents inheritance of mitochondrial diseases. He discovered a new way of creating human stem cells from skin cells. Early life Mitalipov was born in 1961 in Almaty, Kazakhstan, then part of the Soviet Union. He is of Uyghur ancestry. He served two years in Soviet military, beginning in 1979, as an army radio technician. Education After the military, Mitalipov studied genetics at the Timiryazev Agricultural Academy in Moscow and also played blues guitar in a cover band to pay the bills. After his graduation from t ...
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The New York Times
''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid digital subscribers. It also is a producer of popular podcasts such as '' The Daily''. Founded in 1851 by Henry Jarvis Raymond and George Jones, it was initially published by Raymond, Jones & Company. The ''Times'' has won 132 Pulitzer Prizes, the most of any newspaper, and has long been regarded as a national " newspaper of record". For print it is ranked 18th in the world by circulation and 3rd in the U.S. The paper is owned by the New York Times Company, which is publicly traded. It has been governed by the Sulzberger family since 1896, through a dual-class share structure after its shares became publicly traded. A. G. Sulzberger, the paper's publisher and the company's chairman, is the fifth generation of the family to head the pa ...
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Kolkhoz
A kolkhoz ( rus, колхо́з, a=ru-kolkhoz.ogg, p=kɐlˈxos) was a form of collective farm in the Soviet Union. Kolkhozes existed along with state farms or sovkhoz., a contraction of советское хозяйство, soviet ownership or state ownership, sovetskoye khozaystvo. Russian plural: ''sovkhozy''; anglicized plural: ''sovkhozes''. These were the two components of the socialized farm sector that began to emerge in Soviet agriculture after the October Revolution of 1917, as an antithesis both to the feudal structure of impoverished serfdom and aristocratic landlords and to individual or family farming. The 1920s were characterized by spontaneous emergence of collective farms, under influence of traveling propaganda workers. Initially, a collective farm resembled an updated version of the traditional Russian "commune", the generic "farming association" (''zemledel’cheskaya artel’''), the Association for Joint Cultivation of Land (TOZ), and finally the kolkhoz. T ...
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National Geographic (magazine)
''National Geographic'' (formerly the ''National Geographic Magazine'', sometimes branded as NAT GEO) is a popular American monthly magazine published by National Geographic Partners. Known for its photojournalism, it is one of the most widely read magazines of all time. The magazine was founded in 1888 as a scholarly journal, nine months after the establishment of the society, but is now a popular magazine. In 1905, it began including pictures, a style for which it became well-known. Its first color photos appeared in the 1910s. During the Cold War, the magazine committed itself to present a balanced view of the physical and human geography of countries beyond the Iron Curtain. Later, the magazine became outspoken on environmental issues. Since 2019, controlling interest has been held by The Walt Disney Company. Topics of features generally concern geography, history, nature, science, and world culture. The magazine is well known for its distinctive appearance: a thick squa ...
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Discover (magazine)
''Discover'' is an American general audience science magazine launched in October 1980 by Time Inc. It has been owned by Kalmbach Publishing since 2010. History Founding ''Discover'' was created primarily through the efforts of ''Time'' magazine editor Leon Jaroff. He noticed that magazine sales jumped every time the cover featured a science topic. Jaroff interpreted this as a considerable public interest in science, and in 1971, he began agitating for the creation of a science-oriented magazine. This was difficult, as a former colleague noted, because "Selling science to people who graduated to be managers was very difficult".Hevesi, Dennis"Leon Jaroff, Editor at Time and Discover Magazines, Dies at 85" ''The New York Times'', 21 October 2012 Jaroff's persistence finally paid off, and ''Discover'' magazine published its first edition in 1980. ''Discover'' was originally launched into a burgeoning market for science magazines aimed at educated non-professionals, intended to ...
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Time (magazine)
''Time'' (stylized in all caps) is an American news magazine based in New York City. For nearly a century, it was published Weekly newspaper, weekly, but starting in March 2020 it transitioned to every other week. It was first published in New York City on March 3, 1923, and for many years it was run by its influential co-founder, Henry Luce. A European edition (''Time Europe'', formerly known as ''Time Atlantic'') is published in London and also covers the Middle East, Africa, and, since 2003, Latin America. An Asian edition (''Time Asia'') is based in Hong Kong. The South Pacific edition, which covers Australia, New Zealand, and the Pacific Islands, is based in Sydney. Since 2018, ''Time'' has been published by Time USA, LLC, owned by Marc Benioff, who acquired it from Meredith Corporation. History ''Time'' has been based in New York City since its first issue published on March 3, 1923, by Briton Hadden and Henry Luce. It was the first weekly news magazine in the United St ...
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Science (magazine)
''Science'', also widely referred to as ''Science Magazine'', is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, is currently circulated weekly and has a subscriber base of around 130,000. Because institutional subscriptions and online access serve a larger audience, its estimated readership is over 400,000 people. ''Science'' is based in Washington, D.C., United States, with a second office in Cambridge, UK. Contents The major focus of the journal is publishing important original scientific research and research reviews, but ''Science'' also publishes science-related news, opinions on science policy and other matters of interest to scientists and others who are concerned with the wide implications of science and technology. Unlike most scientific journals, which focus on a specific field, ''Science'' and its rival ''Nature'' cover the full rang ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ...
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Cell (journal)
''Cell'' is a peer-reviewed scientific journal publishing research papers across a broad range of disciplines within the life sciences. Areas covered include molecular biology, cell biology, systems biology, stem cells, developmental biology, genetics and genomics, proteomics, cancer research, immunology, neuroscience, structural biology, microbiology, virology, physiology, biophysics, and computational biology. The journal was established in 1974 by Benjamin LewinElsevier: ''Cell'': Home
(accessed 12 December 2008)
and is published twice monthly by , an imprint of

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Rhesus Macaque
The rhesus macaque (''Macaca mulatta''), colloquially rhesus monkey, is a species of Old World monkey. There are between six and nine recognised subspecies that are split between two groups, the Chinese-derived and the Indian-derived. Generally brown or grey in colour, it is in length with a tail and weighs . It is native to South, Central, and Southeast Asia and has the widest geographic range of all non-human primates, occupying a great diversity of altitudes and a great variety of habitats, from grasslands to arid and forested areas, but also close to human settlements. Feral colonies are found in the United States, thought to be either released by humans or escapees after hurricanes destroyed zoo and wildlife park facilities. The rhesus macaque is diurnal, arboreal, and terrestrial. It is mostly herbivorous, mainly eating fruit, but will also consume seeds, roots, buds, bark, and cereals. Studies show almost 100 different plant species in its diet. Rhesus macaques are gener ...
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Three-parent Baby
Mitochondrial replacement therapy (MRT), sometimes called mitochondrial donation, is the replacement of mitochondria in one or more cells to prevent or ameliorate disease. MRT originated as a special form of in vitro fertilisation in which some or all of the future baby's mitochondrial DNA (mtDNA) comes from a third party. This technique is used in cases when mothers carry genes for mitochondrial diseases. The therapy is approved for use in the United Kingdom.Index page
with links to summaries includin
one page summary flyer
A second ...
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Spindle Transfer
Mitochondrial replacement therapy (MRT), sometimes called mitochondrial donation, is the replacement of Mitochondrion, mitochondria in one or more cells to prevent or ameliorate disease. MRT originated as a special form of in vitro fertilisation in which some or all of the future baby's mitochondrial DNA (mtDNA) comes from a third party. This technique is used in cases when mothers carry genes for mitochondrial diseases. The therapy is approved for use in the United Kingdom. the HFEA issued their regulations in December 2016 and granted their first license (to Centre for Life, Newcastle Fertility Centre; Newcastle upon Tyne Hospital NHS Foundation Trust lead by Dr Jane Stewart as Person Responsible to the HFEA) in March 2017. Between August 2017 and January 2019, the HFEA received 15 requests from women to undergo MRT, of which 14 were granted. As of 2020, if children have been born from these procedures, the details have not been published because of the wishes of the parents. Dou ...
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Mitochondrial Disease
Mitochondrial disease is a group of disorders caused by mitochondrial dysfunction. Mitochondria are the organelles that generate energy for the cell and are found in every cell of the human body except red blood cells. They convert the energy of food molecules into the ATP that powers most cell functions. Mitochondrial diseases take on unique characteristics both because of the way the diseases are often inherited and because mitochondria are so critical to cell function. A subclass of these diseases that have neuromuscular symptoms are known as mitochondrial myopathies. Types Examples of mitochondrial diseases include: * Mitochondrial myopathy * Diabetes mellitus and deafness (DAD) ** this combination at an early age can be due to mitochondrial disease ** Diabetes mellitus and deafness can be found together for other reasons * Leber's hereditary optic neuropathy (LHON) ** visual loss beginning in young adulthood ** eye disorder characterized by progressive loss of central v ...
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