Shire Plc
Shire plc was a UK-founded Jersey-registered specialty biopharmaceutical company. Originating in the United Kingdom with an operational base in the United States, its brands and products included Vyvanse, Lialda, and Adderall XR. Shire was acquired by Takeda Pharmaceutical Company on 8 January 2019. Shire was a global biotechnology company focused on serving people with rare diseases and other highly specialized conditions. The company's products were available in more than 100 countries across core therapeutic areas including Hematology, Immunology, Neuroscience, Lysosomal Storage Disorders, Gastrointestinal / Internal Medicine / Endocrine and Hereditary Angioedema; a growing franchise in Oncology; and an emerging, innovative pipeline in Ophthalmics. The original corporate headquarters was located in Basingstoke, Hampshire, England. Main offices are located in Dublin, Ireland, the United States in Cambridge, Massachusetts, and Chicago, Illinois, and in Zug, Switzerland. In ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Subsidiary
A subsidiary, subsidiary company or daughter company is a company owned or controlled by another company, which is called the parent company or holding company. Two or more subsidiaries that either belong to the same parent company or having a same management being substantially controlled by same entity/group are called sister companies. The subsidiary can be a company (usually with limited liability) and may be a government- or state-owned enterprise. They are a common feature of modern business life, and most multinational corporations organize their operations in this way. Examples of holding companies are Berkshire Hathaway, Jefferies Financial Group, The Walt Disney Company, Warner Bros. Discovery, or Citigroup; as well as more focused companies such as IBM, Xerox, and Microsoft. These, and others, organize their businesses into national and functional subsidiaries, often with multiple levels of subsidiaries. Details Subsidiaries are separate, distinct legal entities f ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Osteoporosis
Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to bone fragility, and consequent increase in fracture risk. It is the most common reason for a broken bone among the elderly. Bones that commonly break include the vertebrae in the spine, the bones of the forearm, and the hip. Until a broken bone occurs there are typically no symptoms. Bones may weaken to such a degree that a break may occur with minor stress or spontaneously. After the broken bone heals, the person may have chronic pain and a decreased ability to carry out normal activities. Osteoporosis may be due to lower-than-normal maximum bone mass and greater-than-normal bone loss. Bone loss increases after the menopause due to lower levels of estrogen, and after ' andropause' due to lower levels of testosterone. Osteoporosis may also occur due to a number of diseases or treatments, including alcoholism, anorexia, hyperthyroidism, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Calcichew-D3
Calcium/cholecalciferol is a combination of a calcium salt (usually calcium carbonate) and vitamin D3 (cholecalciferol). It is used to prevent and treat lack of calcium and vitamin D in the elderly, as well for osteoporosis in combination with other medications. 18 February 2021 In 2020, the combination, calcium/vitamin D was the 215th most commonly prescribed medication in the United States, with more than 2million prescriptions. Adverse effects Possible side effects include gastrointestinal problems, for example nausea and constipation. If very high doses are taken, signs of hypercalcaemia (abnormally high blood calcium levels) have been described, such as stomach pain, vomiting, thirst, and tiredness. Extreme or long-term or overdose can theoretically result in hypervitaminosis D, kidney stones, chronic kidney disease, and calcinosis. Interactions Calcium forms complexes with a number of pharmaceutical drugs, reducing their bioavailability; among them are tetracyclines, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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London Stock Exchange
London Stock Exchange (LSE) is a stock exchange in the City of London, England, United Kingdom. , the total market value of all companies trading on LSE was £3.9 trillion. Its current premises are situated in Paternoster Square close to St Paul's Cathedral in the City of London. Since 2007, it has been part of the London Stock Exchange Group (LSEG, that it also lists ()). The LSE was the most-valued stock exchange in Europe from 2003 when records began till Autumn 2022, when the Paris exchange was briefly larger, until the LSE retook its position as Europe’s largest stock exchange 10 days later. History Coffee House The Royal Exchange had been founded by English financier Thomas Gresham and Sir Richard Clough on the model of the Antwerp Bourse. It was opened by Elizabeth I of England in 1571. During the 17th century, stockbrokers were not allowed in the Royal Exchange due to their rude manners. They had to operate from other establishments in the vicinity, notably Jona ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rolf Stahel
Shire plc was a UK-founded Jersey-registered specialty biopharmaceutical company. Originating in the United Kingdom with an operational base in the United States, its brands and products included Vyvanse, Lialda, and Adderall XR. Shire was acquired by Takeda Pharmaceutical Company on 8 January 2019. Shire was a global biotechnology company focused on serving people with rare diseases and other highly specialized conditions. The company's products were available in more than 100 countries across core therapeutic areas including Hematology, Immunology, Neuroscience, Lysosomal Storage Disorders, Gastrointestinal / Internal Medicine / Endocrine and Hereditary Angioedema; a growing franchise in Oncology; and an emerging, innovative pipeline in Ophthalmics. The original corporate headquarters was located in Basingstoke, Hampshire, England. Main offices are located in Dublin, Ireland, the United States in Cambridge, Massachusetts, and Chicago, Illinois, and in Zug, Switzerland. In ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Harry Stratford
Harry Thomas Stratford OBE (born 1948) is the founder of Shire, one of the United Kingdom's largest pharmaceutical businesses. Career Educated at the University of London, Harry Stratford founded Shire Pharmaceticals in 1986 and remained its Chief Executive until 1994. In 1995 he founded ''ProStakan'', another pharmaceutical business, and was Chief Executive there until he became Executive Chairman in 2004; he was then Non-Executive Chairman The chairperson, also chairman, chairwoman or chair, is the presiding officer of an organized group such as a board, committee, or deliberative assembly. The person holding the office, who is typically elected or appointed by members of the grou ... from 2006 until he retired at the end of 2007. In 2008 he became a Non-Executive Director of ''Merrion Pharmaceuticals''. References 1948 births Living people Alumni of the University of London British businesspeople Officers of the Order of the British Empire {{UK-business-bio ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Shire Location In Lexington MA
Shire is a traditional term for an administrative division of land in Great Britain and some other English-speaking countries such as Australia and New Zealand. It is generally synonymous with county. It was first used in Wessex from the beginning of Anglo-Saxon settlement, and spread to most of the rest of England in the tenth century. In some rural parts of Australia, a shire is a local government area; however, in Australia it is not synonymous with a "county", which is a lands administrative division. Etymology The word ''shire'' derives from the Old English , from the Proto-Germanic ( goh, sćira), denoting an 'official charge' a 'district under a governor', and a 'care'. In the UK, ''shire'' became synonymous with ''county'', an administrative term introduced to England through the Norman Conquest in the later part of the eleventh century. In contemporary British usage, the word ''counties'' also refers to shires, mainly in places such as Shire Hall. In regions with ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Deerfield, Illinois
Deerfield is a north shore suburb of Chicago in Lake County, Illinois, United States, with a small portion extending into Cook County, Illinois. The population was 19,196 at the 2020 census. Deerfield is home to the headquarters of Walgreens Boots Alliance, Baxter Healthcare, and Fortune Brands Home & Security. Deerfield is often listed among some of the wealthiest and highest earning places in Illinois and the Midwest. The per capita income of the village is $68,101 and the median household income is $143,729. History Beginnings Originally populated by the Bodéwadmiakiwen ( Potawatomi), Myaamia (Miami), Kiikaapoi ( Kickapoo), Peoria, and Očhéthi Šakówiŋ (Oglala Sioux) Native Americans, the area was settled by Horace Lamb and Jacob B. Cadwell in 1835 and named Cadwell's Corner. A shopping center located on the site of Cadwell's farm at Waukegan Road and Lake Cook Road still bears that name. The area grew because of the navigable rivers in the area, notably the Des Plai ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Social Circle, Georgia
Social Circle is a city in southern Walton County, extending into Newton County, in the U.S. state of Georgia, 45 miles east of Atlanta. History It is unclear why the name "Social Circle" was applied to this place. According to tradition, Social Circle was named from an incident in which a group of people living in the settlement offered water to a weary traveler, whose response was "This certainly is a social circle". The city also officially notes that a citizen of another village community which was already known by the name of Social Circle joined the settlement in its early days. Social Circle was incorporated as a town in 1869, and as a city in 1904. Geographical data According to the United States Census Bureau, the city has a total area of , of which are land and (100%) is water. A CSX Transportation line maintenance facility operates in the city's railroad station. The city's railyard contains one of the relatively few remaining concrete coaling towers in the sout ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lexington, Massachusetts
Lexington is a suburban town in Middlesex County, Massachusetts, United States. It is 10 miles (16 km) from Downtown Boston. The population was 34,454 as of the 2020 census. The area was originally inhabited by Native Americans, and was first settled by Europeans in 1641 as a farming community. Lexington is well known as the site of the first shots of the American Revolutionary War, in the Battle of Lexington on April 19, 1775, where the " Shot heard 'round the world" took place. It is home to Minute Man National Historical Park. History Indigenous history Native Americans inhabited the area that would become Lexington for thousands of years prior to European colonization of the Americas, as attested by a woodland era archaeological site near Loring Hill south of the town center. At the time of European contact, the area may have been a border region between Naumkeag or Pawtucket to the northeast, Massachusett to the south, and Nipmuc to the west, though the land was ev ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chicago
(''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = Country , subdivision_name = United States , subdivision_type1 = State , subdivision_type2 = Counties , subdivision_name1 = Illinois , subdivision_name2 = Cook and DuPage , established_title = Settled , established_date = , established_title2 = Incorporated (city) , established_date2 = , founder = Jean Baptiste Point du Sable , government_type = Mayor–council , governing_body = Chicago City Council , leader_title = Mayor , leader_name = Lori Lightfoot ( D) , leader_title1 = City Clerk , leader_name1 = Anna Valencia ( D) , unit_pref = Imperial , area_footnotes = , area_tot ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |