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Serial Femtosecond Crystallography
Serial femtosecond crystallography (SFX) is a form of X-ray crystallography developed for use at X-ray free-electron lasers (XFELs). Single pulses at free-electron lasers are bright enough to generate resolvable Bragg diffraction from sub-micron crystals. However, these pulses also destroy the crystals, meaning that a full data set involves collecting diffraction from many crystals. This method of data collection is referred to as ''serial'', referencing a row of crystals streaming across the X-ray beam, one at a time. History While the idea of serial crystallography had been proposed earlier, it was first demonstrated with XFELs by Chapman et al. at the Linac Coherent Light Source (LCLS) in 2011. This method has since been extended to solve unknown structures, perform time-resolved experiments, and later even brought back to synchrotron X-ray sources. Methods In comparison to conventional crystallography, where a single (relatively large) crystal is rotated in order to colle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
X-ray Crystallography
X-ray crystallography is the experimental science determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract into many specific directions. By measuring the angles and intensities of these diffracted beams, a crystallographer can produce a three-dimensional picture of the density of electrons within the crystal. From this electron density, the mean positions of the atoms in the crystal can be determined, as well as their chemical bonds, their crystallographic disorder, and various other information. Since many materials can form crystals—such as salts, metals, minerals, semiconductors, as well as various inorganic, organic, and biological molecules—X-ray crystallography has been fundamental in the development of many scientific fields. In its first decades of use, this method determined the size of atoms, the lengths and types of chemical bonds, and the atomic-scale differences among various mat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Free-electron Laser
A free-electron laser (FEL) is a (fourth generation) light source producing extremely brilliant and short pulses of radiation. An FEL functions and behaves in many ways like a laser, but instead of using stimulated emission from atomic or molecular excitations, it employs relativistic electrons as a gain medium. Radiation is generated by a ''bunch'' of electrons passing through a magnetic structure (called undulator or wiggler). In an FEL, this radiation is further amplified as the radiation re-interacts with the electron bunch such that the electrons start to emit coherently, thus allowing an exponential increase in overall radiation intensity. As electron kinetic energy and undulator parameters can be adapted as desired, free-electron lasers are tunable and can be built for a wider frequency range than any other type of laser, currently ranging in wavelength from microwaves, through terahertz radiation and infrared, to the visible spectrum, ultraviolet, and X-ray. The first ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States National Agricultural Library
The United States National Agricultural Library (NAL) is one of the world's largest agricultural research libraries, and serves as a national library of the United States and as the library of the United States Department of Agriculture. Located in Beltsville, Maryland, it is one of five national libraries of the United States (along with the Library of Congress, the National Library of Medicine, the National Transportation Library, and the National Library of Education). It is also the coordinator for the Agriculture Network Information Center (AgNIC), a national network of state land-grant institutions and coordinator for the U.S. Department of Agriculture (USDA) field libraries. NAL was established on May 15, 1862, by the signing of the Organic Act by Abraham Lincoln. It served as a departmental library until 1962, when the Secretary of Agriculture officially designated it as the National Agricultural Library. The first librarian, appointed in 1867, was Aaron B. Grosh, one ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sfx Schematic Dffn
SFX may refer to: Entertainment * Special effects (usually visual), illusions used in film, television, and entertainment * Sound effects, sounds that are artificially created or enhanced * ''SFX'' (magazine), a British magazine covering the topics of science fiction and fantasy * SFX (Science Fiction Expo), a convention in Toronto, Canada * SFX Entertainment, American promoter * ''S-F-X'' (album), a 1984 album by Haruomi Hosono * SFX, a prototype Super NES video game console * Super FX, a coprocessor chip used in some Super NES video game cartridges * Use in comics of onomatopoeic, conventions to convey sound events accompanying visuals and dialogue Computing * Self-extracting archive, a compressed file with an embedded executable to decompress itself * SFX (software), an OpenURL link server * SFX (PSU), a design for a small form factor (SFF) power supply casing * Small form factor (desktop and motherboard), a term covering smaller-than traditional form factors for comput ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Linac Coherent Light Source
SLAC National Accelerator Laboratory, originally named the Stanford Linear Accelerator Center, is a United States Department of Energy National Laboratory operated by Stanford University under the programmatic direction of the U.S. Department of Energy Office of Science and located in Menlo Park, California. It is the site of the Stanford Linear Accelerator, a 3.2 kilometer (2-mile) linear accelerator constructed in 1966 and shut down in the 2000s, that could accelerate electrons to energies of 50 GeV. Today SLAC research centers on a broad program in atomic and solid-state physics, chemistry, biology, and medicine using X-rays from synchrotron radiation and a free-electron laser as well as experimental and theoretical research in elementary particle physics, astroparticle physics, and cosmology. History Founded in 1962 as the Stanford Linear Accelerator Center, the facility is located on of Stanford University-owned land on Sand Hill Road in Menlo Park, Californi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Miller Index
Miller indices form a notation system in crystallography for lattice planes in crystal (Bravais) lattices. In particular, a family of lattice planes of a given (direct) Bravais lattice is determined by three integers ''h'', ''k'', and ''ℓ'', the ''Miller indices''. They are written (hkℓ), and denote the family of (parallel) lattice planes (of the given Bravais lattice) orthogonal to \mathbf_ = h\mathbf + k\mathbf + \ell\mathbf, where \mathbf are the basis or primitive translation vectors of the reciprocal lattice for the given Bravais lattice. (Note that the plane is not always orthogonal to the linear combination of direct or original lattice vectors h\mathbf + k\mathbf + \ell\mathbf because the direct lattice vectors need not be mutually orthogonal.) This is based on the fact that a reciprocal lattice vector \mathbf (the vector indicating a reciprocal lattice point from the reciprocal lattice origin) is the wavevector of a plane wave in the Fourier series of a spatial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gas Dynamic Virtual Nozzle
Gas is one of the four fundamental states of matter (the others being solid, liquid, and plasma). A pure gas may be made up of individual atoms (e.g. a noble gas like neon), elemental molecules made from one type of atom (e.g. oxygen), or compound molecules made from a variety of atoms (e.g. carbon dioxide). A gas mixture, such as air, contains a variety of pure gases. What distinguishes a gas from liquids and solids is the vast separation of the individual gas particles. This separation usually makes a colourless gas invisible to the human observer. The gaseous state of matter occurs between the liquid and plasma states, the latter of which provides the upper temperature boundary for gases. Bounding the lower end of the temperature scale lie degenerative quantum gases which are gaining increasing attention. High-density atomic gases super-cooled to very low temperatures are classified by their statistical behavior as either Bose gases or Fermi gases. For a comprehe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lipid Polymorphism
Polymorphism in biophysics is the ability of lipids to aggregate in a variety of ways, giving rise to structures of different shapes, known as "phases". This can be in the form of sphere of lipid molecules (micelles), pairs of layers that face one another (lamellar phase, observed in biological systems as a lipid bilayer), a tubular arrangement (hexagonal), or various cubic phases (Fdm, Imm, Iam, Pnm, and Pmm being those discovered so far). More complicated aggregations have also been observed, such as rhombohedral, tetragonal and orthorhombic phases. It forms an important part of current academic research in the fields of membrane biophysics (polymorphism), biochemistry (biological impact) and organic chemistry (synthesis). Determination of the topology of a lipid system is possible by a number of methods, the most reliable of which is x-ray diffraction. This uses a beam of x-rays that are scattered by the sample, giving a diffraction pattern as a set of rings. The ratio of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kapton
Structure of poly-oxydiphenylene-pyromellitimide Kapton insulating pads for mounting electronic parts on a heat sink Kapton is a polyimide film used in flexible printed circuits (flexible electronics) and space blankets, which are used on spacecraft, satellites, and various space instruments. Invented by the DuPont Corporation in the 1960s, Kapton remains stable (in isolation) across a wide range of temperatures, from . History Kapton was invented by the DuPont Corporation in the 1960s. The name ''Kapton'' is a registered trademark of E. I. du Pont de Nemours and Company. Chemistry and variants Kapton synthesis is an example of the use of a dianhydride in step polymerization. The intermediate polymer, known as a ''poly(amic acid)'', is soluble because of strong hydrogen bonds to the polar solvents usually employed in the reaction. The ring closure is carried out at high temperatures of . The chemical name for Kapton K and HN is ''poly (4,4'-oxydiphenylene-pyromellit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
