Sclerotium Rolfsi
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Sclerotium Rolfsi
A sclerotium (; (), is a compact mass of hardened fungal mycelium containing food reserves. One role of sclerotia is to survive environmental extremes. In some higher fungi such as ergot, sclerotia become detached and remain dormant until favorable growth conditions return. Sclerotia initially were mistaken for individual organisms and described as separate species until Louis René Tulasne proved in 1853 that sclerotia are only a stage in the life cycle of some fungi. Further investigation showed that this stage appears in many fungi belonging to many diverse groups. Sclerotia are important in the understanding of the life cycle and reproduction of fungi, as a food source, as medicine (for example, ergotamine), and in agricultural blight management. Examples of fungi that form sclerotia are ergot (''Claviceps purpurea''), ''Polyporus tuberaster'', ''Psilocybe mexicana'', ''Sclerotium delphinii'' and many species in Sclerotiniaceae. Although not fungal, the plasmodium of slime m ...
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Claviceps Purpurea
''Claviceps purpurea'' is an ergot fungus that grows on the ears of rye and related cereal and forage plants. Consumption of grains or seeds contaminated with the survival structure of this fungus, the ergot sclerotium, can cause ergotism in humans and other mammals. ''C. purpurea'' most commonly affects outcrossing species such as rye (its most common host), as well as triticale, wheat and barley. It affects oats only rarely. Life cycle An ''ergot kernel'' called ''Sclerotium clavus'' develops when a floret of flowering grass or cereal is infected by an ascospore of ''C. purpurea''. The infection process mimics a pollen grain growing into an ovary during fertilization. Because infection requires access of the fungal spore to the stigma, plants infected by ''C. purpurea'' are mainly outcrossing species with open flowers, such as rye (''Secale cereale'') and Alopecurus. The proliferating fungal mycelium then destroys the plant ovary and connects with the vascular bundle o ...
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Cleistothecium
An ascocarp, or ascoma (), is the fruiting body ( sporocarp) of an ascomycete phylum fungus. It consists of very tightly interwoven hyphae and millions of embedded asci, each of which typically contains four to eight ascospores. Ascocarps are most commonly bowl-shaped (apothecia) but may take on a spherical or flask-like form that has a pore opening to release spores (perithecia) or no opening (cleistothecia). Classification The ascocarp is classified according to its placement (in ways not fundamental to the basic taxonomy). It is called ''epigeous'' if it grows above ground, as with the morels, while underground ascocarps, such as truffles, are termed ''hypogeous''. The structure enclosing the hymenium is divided into the types described below (apothecium, cleistothecium, etc.) and this character ''is'' important for the taxonomic classification of the fungus. Apothecia can be relatively large and fleshy, whereas the others are microscopic—about the size of flecks of ...
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Ascospores
An ascus (; ) is the sexual spore-bearing cell produced in ascomycete fungi. Each ascus usually contains eight ascospores (or octad), produced by meiosis followed, in most species, by a mitotic cell division. However, asci in some genera or species can occur in numbers of one (e.g. ''Monosporascus cannonballus''), two, four, or multiples of four. In a few cases, the ascospores can bud off conidia that may fill the asci (e.g. ''Tympanis'') with hundreds of conidia, or the ascospores may fragment, e.g. some '' Cordyceps'', also filling the asci with smaller cells. Ascospores are nonmotile, usually single celled, but not infrequently may be coenocytic (lacking a septum), and in some cases coenocytic in multiple planes. Mitotic divisions within the developing spores populate each resulting cell in septate ascospores with nuclei. The term ocular chamber, or oculus, refers to the epiplasm (the portion of cytoplasm not used in ascospore formation) that is surrounded by the "bourr ...
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Claviceps Purpurea - Köhler–s Medizinal-Pflanzen-185-en
Ergot ( ) or ergot fungi refers to a group of fungi of the genus ''Claviceps''. The most prominent member of this group is ''Claviceps purpurea'' ("rye ergot fungus"). This fungus grows on rye and related plants, and produces alkaloids that can cause ergotism in humans and other mammals who consume grains contaminated with its fruiting structure (called ''ergot sclerotium''). ''Claviceps'' includes about 50 known species, mostly in the tropical regions. Economically significant species include ''C. purpurea'' (parasitic on grasses and cereals), ''C. fusiformis'' (on pearl millet, buffel grass), ''C. paspali'' (on dallis grass), ''C. africana'' (on sorghum), and ''C. lutea'' (on paspalum). ''C. purpurea'' most commonly affects outcrossing species such as rye (its most common host), as well as triticale, wheat, and barley. It affects oats only rarely. ''C. purpurea'' has at least three races or varieties, which differ in their host specificity: *G1 — land grasses of open m ...
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Medicinal Mushrooms
Medicinal fungi are fungi that contain metabolites or can be induced to produce metabolites through biotechnology to develop prescription drugs. Compounds successfully developed into drugs or under research include antibiotics, anti-cancer drugs, cholesterol and ergosterol synthesis inhibitors, psychotropic drugs, immunosuppressants and fungicides. History Although fungi products have long been used in traditional medicine, the ability to identify beneficial properties and then extract the active ingredient started with the discovery of penicillin by Alexander Fleming in 1928. Since that time, many potential antibiotics were discovered and the potential for various fungi to synthesize biologically active molecules useful in various clinical therapies has been under research. Pharmacological research identified antifungal, antiviral, and antiprotozoan compounds from fungi. '' Ganoderma lucidum'', known in Chinese as líng zhī ("spirit plant"), and in Japanese as mannentake ("10 ...
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Ethnomycology
Ethnomycology is the study of the historical uses and sociological impact of fungi and can be considered a subfield of ethnobotany or ethnobiology. Although in theory the term includes fungi used for such purposes as tinder, medicine (medicinal mushrooms) and food (including yeast), it is often used in the context of the study of psychoactive mushrooms such as psilocybin mushrooms, the ''Amanita muscaria'' mushroom, and the ergot fungus. American banker Robert Gordon Wasson pioneered interest in this field of study in the late 1950s, when he and his wife became the first Westerners on record allowed to participate in a mushroom ''velada'', held by the Mazatec '' curandera'' María Sabina. The biologist Richard Evans Schultes is also considered an ethnomycological pioneer. Later researchers in the field include Terence McKenna, Albert Hofmann, Ralph Metzner, Carl Ruck, Blaise Daniel Staples, Giorgio Samorini, Keewaydinoquay Peschel, John Marco Allegro, Clark Heinrich, John W. Allen ...
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Pleurotus Tuber-regium
''Pleurotus tuber-regium'', the king tuber mushroom, is an edible gilled fungus native to the tropics, including Africa, Asia, and Australasia. It has been shown to be a distinct species incapable of cross-breeding and phylogenetically removed from other species of ''Pleurotus''. ''Pleurotustuber-regium'' is a saprotroph found on dead wood, including '' Daniellia'' trees in Africa. As the fungus consumes the wood, it produces a sclerotium, or storage tuber, either within the decaying wood or in the underlying soil. These sclerotia are round, dark brown with white interiors, and up to 30 cm wide. The fruiting bodies then emerge from the sclerotium. Both the sclerotium and the fruiting bodies are edible. In addition to being saprotrophic, ''P. tuber-regium'' is also nematophagous, catching nematodes by paralyzing them with a toxin. ''Pleurotus tuber-regium'' has a history of economic importance in Africa as food and as a medicinal mushroom. Industrial cultivation is not yet ...
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Edema
Edema, also spelled oedema, and also known as fluid retention, dropsy, hydropsy and swelling, is the build-up of fluid in the body's Tissue (biology), tissue. Most commonly, the legs or arms are affected. Symptoms may include skin which feels tight, the area may feel heavy, and joint stiffness. Other symptoms depend on the underlying cause. Causes may include Chronic venous insufficiency, venous insufficiency, heart failure, kidney problems, hypoalbuminemia, low protein levels, liver problems, deep vein thrombosis, infections, angioedema, certain medications, and lymphedema. It may also occur after prolonged sitting or standing and during menstruation or pregnancy. The condition is more concerning if it starts suddenly, or pain or shortness of breath is present. Treatment depends on the underlying cause. If the underlying mechanism involves Hypernatremia, sodium retention, decreased salt intake and a diuretic may be used. Elevating the legs and support stockings may be useful ...
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Alkaloids
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids
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Alkaloids are produced by a large variety of organisms including , ,

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Ergotism
Ergotism (pron. ) is the effect of long-term ergot poisoning, traditionally due to the ingestion of the alkaloids produced by the ''Claviceps purpurea'' fungus—from the Latin "club" or clavus "nail" and for "head", i.e. the purple club-headed fungus—that infects rye and other cereals, and more recently by the action of a number of ergoline-based drugs. It is also known as ergotoxicosis, ergot poisoning, and Saint Anthony's fire. Signs and symptoms The symptoms can be roughly divided into convulsive symptoms and gangrenous symptoms. Convulsive Convulsive symptoms include painful seizures and spasms, diarrhea, paresthesias, itching, mental effects including mania or psychosis, headaches, nausea and vomiting. Usually the gastrointestinal effects precede central nervous system effects. Gangrenous The dry gangrene is a result of vasoconstriction induced by the ergotamine-ergocristine alkaloids of the fungus. It affects the more poorly vascularized distal structures, such as ...
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Middle Ages
In the history of Europe, the Middle Ages or medieval period lasted approximately from the late 5th to the late 15th centuries, similar to the post-classical period of global history. It began with the fall of the Western Roman Empire and transitioned into the Renaissance and the Age of Discovery. The Middle Ages is the middle period of the three traditional divisions of Western history: classical antiquity, the medieval period, and the modern period. The medieval period is itself subdivided into the Early, High, and Late Middle Ages. Population decline, counterurbanisation, the collapse of centralized authority, invasions, and mass migrations of tribes, which had begun in late antiquity, continued into the Early Middle Ages. The large-scale movements of the Migration Period, including various Germanic peoples, formed new kingdoms in what remained of the Western Roman Empire. In the 7th century, North Africa and the Middle East—most recently part of the Eastern Ro ...
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Edmond Tulasne
Louis René Étienne Tulasne, a.k.a. Edmond Tulasne (12 September 1815 – 22 December 1885) was a French botanist and mycologist born in Azay-le-Rideau. He originally studied law at Poitiers, but his interest later turned to botany. As a young man he assisted botanist Auguste de Saint-Hilaire (1779–1853) with studies of Brazilian flora. From 1842 until 1872 he worked as a naturalist at the Muséum national d'histoire naturelle in Paris. In 1854 he succeeded Adrien-Henri de Jussieu (1797–1853) as a member of the Académie des sciences. He died in Hyères on 22 December 1885, age 70. Tulasne's specialized study was the science of mycology. His microscopic investigation of fungi, particularly parasitic species, contributed much to the understanding on the complexities of their nature and development. He is credited with introducing the concept of " pleomorphy" in regard to fungi.
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