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Scintillation Counter
A scintillation counter is an instrument for detecting and measuring ionizing radiation by using the Electron excitation, excitation effect of incident radiation on a Scintillation (physics), scintillating material, and detecting the resultant light pulses. It consists of a scintillator which generates photons in response to incident radiation, a sensitive photodetector (usually a photomultiplier tube (PMT), a charge-coupled device (CCD) camera, or a photodiode), which converts the light to an electrical signal and electronics to process this signal. Scintillation counters are widely used in radiation protection, assay of radioactive materials and physics research because they can be made inexpensively yet with good quantum efficiency, and can measure both the intensity and the Electronvolt, energy of incident radiation. History The first electronic scintillation counter was invented in 1944 by Samuel Curran, Sir Samuel Curran whilst he was working on the Manhattan Project at th ...
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Phosphorescence
Phosphorescence is a type of photoluminescence related to fluorescence. When exposed to light (radiation) of a shorter wavelength, a phosphorescent substance will glow, absorbing the light and reemitting it at a longer wavelength. Unlike fluorescence, a phosphorescent material does not immediately reemit the radiation it absorbs. Instead, a phosphorescent material absorbs some of the radiation energy and reemits it for a much longer time after the radiation source is removed. In a general sense, there is no distinct boundary between the emission times of fluorescence and phosphorescence (i.e.: if a substance glows under a black light it is generally considered fluorescent, and if it glows in the dark it is often simply called phosphorescent). In a modern, scientific sense, the phenomena can usually be classified by the three different mechanisms that produce the light, and the typical timescales during which those mechanisms emit light. Whereas fluorescent materials stop emitti ...
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Anthracene
Anthracene is a solid polycyclic aromatic hydrocarbon (PAH) of formula C14H10, consisting of three fused benzene rings. It is a component of coal tar. Anthracene is used in the production of the red dye alizarin and other dyes, as a scintillator to detect high energy particles, as production of pharmaceutical drugs. Anthracene is colorless but exhibits a blue (400–500 nm peak) fluorescence under ultraviolet radiation. History and etymology Crude anthracene (with a melting point of only 180°) was discovered in 1832 by Jean-Baptiste Dumas and Auguste Laurent who crystalized it from a fraction of coal tar later known as "anthracene oil". Since their (inaccurate) measurements showed the proportions of carbon and hydrogen of it to be the same as in naphthalene, Laurent called it ''paranaphtaline'' in his 1835 publication of the discovery, which is translated to English as paranaphthalene. Two years later, however, he decided to rename the compound to its modern name d ...
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Crystal
A crystal or crystalline solid is a solid material whose constituents (such as atoms, molecules, or ions) are arranged in a highly ordered microscopic structure, forming a crystal lattice that extends in all directions. In addition, macroscopic single crystals are usually identifiable by their geometrical shape, consisting of flat faces with specific, characteristic orientations. The scientific study of crystals and crystal formation is known as crystallography. The process of crystal formation via mechanisms of crystal growth is called crystallization or solidification. The word ''crystal'' derives from the Ancient Greek word (), meaning both "ice" and " rock crystal", from (), "icy cold, frost". Examples of large crystals include snowflakes, diamonds, and table salt. Most inorganic solids are not crystals but polycrystals, i.e. many microscopic crystals fused together into a single solid. Polycrystals include most metals, rocks, ceramics, and ice. A third cat ...
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Charge Amplifier
A charge amplifier is an electronic electric current, current integrator that produces a voltage output proportional to the integrated value of the input current, or the total charge injected. The amplifier offsets the input current using a feedback reference capacitor, and produces an output voltage inversely proportional to the value of the reference capacitor but proportional to the total input charge flowing during the specified time period. The circuit therefore acts as a charge-to-voltage converter. The gain of the circuit depends on the values of the feedback capacitor. The charge amplifier was invented by Walter Kistler in 1950. Design Charge amplifiers are usually constructed using an operational amplifier or other high gain semiconductor circuit with a negative feedback capacitor ''Cf''. Into the inverting node flow the input charge signal ''qin'' and the feedback charge ''qf'' from the output. According to Kirchhoff's circuit laws they compensate each other. :q_=- ...
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Pair Production
Pair production is the creation of a subatomic particle and its antiparticle from a neutral boson. Examples include creating an electron and a positron, a muon and an antimuon, or a proton and an antiproton. Pair production often refers specifically to a photon creating an electron–positron pair near a nucleus. As energy must be conserved, for pair production to occur, the incoming energy of the photon must be above a threshold of at least the total rest mass energy of the two particles created. (As the electron is the lightest, hence, lowest mass/energy, elementary particle, it requires the least energetic photons of all possible pair-production processes.) Conservation of energy and momentum are the principal constraints on the process. All other conserved quantum numbers ( angular momentum, electric charge, lepton number) of the produced particles must sum to zero thus the created particles shall have opposite values of each other. For instance, if one partic ...
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Compton Scattering
Compton scattering (or the Compton effect) is the quantum theory of high frequency photons scattering following an interaction with a charged particle, usually an electron. Specifically, when the photon hits electrons, it releases loosely bound electrons from the outer valence shells of atoms or molecules. The effect was discovered in 1923 by Arthur Holly Compton while researching the scattering of X-rays by light elements, and earned him the Nobel Prize in Physics in 1927. The Compton effect significantly deviated from dominating classical theories, using both special relativity and quantum mechanics to explain the interaction between high frequency photons and charged particles. Photons can interact with matter at the atomic level (e.g. photoelectric effect and Rayleigh scattering), at the nucleus, or with just an electron. Pair production and the Compton effect occur at the level of the electron. When a high frequency photon scatters due to an interaction with a charged part ...
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Photoelectric Effect
The photoelectric effect is the emission of electrons from a material caused by electromagnetic radiation such as ultraviolet light. Electrons emitted in this manner are called photoelectrons. The phenomenon is studied in condensed matter physics, solid state, and quantum chemistry to draw inferences about the properties of atoms, molecules and solids. The effect has found use in electronic devices specialized for light detection and precisely timed electron emission. The experimental results disagree with classical electromagnetism, which predicts that continuous light waves transfer energy to electrons, which would then be emitted when they accumulate enough energy. An alteration in the intensity of light would theoretically change the kinetic energy of the emitted electrons, with sufficiently dim light resulting in a delayed emission. The experimental results instead show that electrons are dislodged only when the light exceeds a certain frequency—regardless of the ligh ...
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Scintillation Detector
A scintillator ( ) is a material that exhibits scintillation (physics), scintillation, the property of luminescence, when excited by ionizing radiation. Luminescent materials, when struck by an incoming particle, absorb its energy and scintillate (i.e. re-emit the absorbed energy in the form of light). Sometimes, the excited state is Metastability, metastable, so the relaxation back down from the excited state to lower states is delayed (necessitating anywhere from a few nanoseconds to hours depending on the material). The process then corresponds to one of two phenomena: delayed fluorescence or phosphorescence. The correspondence depends on the type of transition and hence the wavelength of the emitted optical photon. Principle of operation A scintillation detector or scintillation counter is obtained when a scintillator is coupled to an electronic light sensor such as a photomultiplier tube (PMT), photodiode, or silicon photomultiplier. PMTs absorb the light emitted by the sc ...
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Scintillation Counter Schematic
Scintillation can refer to: *Scintillation (astronomy), atmospheric effects which influence astronomical observations *Interplanetary scintillation, fluctuations of radio waves caused by the solar wind *Scintillation (physics), a flash of light produced in certain materials when they absorb ionizing radiation * Scintillation (radar), an apparent rapid target displacement occurring on radar displays * Scintillation (medicine), a rapidly oscillating pattern of visual distortions, often associated with migraine aura *Scintillation counter, a device that measures ionizing radiation * Scintillating grid illusion, an image in which compounded color contrasts cause an optical illusion of visual artifacts See also *Scintillate (horse) Scintillate (foaled 24 January 1976) was a British Thoroughbred racehorse and Horse breeding#terminology, broodmare best known for winning the British Classic Races, classic Oaks Stakes in 1979. She showed promising form as a two-year-old altho ...
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In Vitro
''In vitro'' (meaning ''in glass'', or ''in the glass'') Research, studies are performed with Cell (biology), cells or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, known as clinical trials, and whole plants. Definition ''In vitro'' (Latin language, Latin for "in glass"; often not italicized in English usage) studies are conducted ...
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In Vivo
Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. Examples of investigations ''in vivo'' include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of non-antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of ''in vivo'' research. ''In vivo'' testing is often employed over ''in vitro'' because it is better suited for observing the overall effects of an experiment on a living subject. In drug discovery, for example, verification of efficacy ''in vivo'' is crucial, because ''in vitro'' assays can sometimes yield misleading results with drug c ...
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