Sceptrin
Sceptrin is a bioactive marine isolate. It has been isolated from the marine sponge ''Agelas conifera'' and appears to have affinity for the bacterial actin equivalent MreB. As such, this compound possess antibiotic potential. See also * Ageliferin * Prokaryotic cytoskeleton The prokaryotic cytoskeleton is the collective name for all structural filaments in prokaryotes. It was once thought that prokaryotic cells did not possess cytoskeletons, but advances in visualization technology and structure determination led t ... References Imidazoles Bromoarenes Halogen-containing natural products Cyclobutanes Antibiotics Carboxamides {{Antibiotic-stub ...
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Biological Activity
In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter. When a drug is a complex chemical mixture, this activity is exerted by the substance's active ingredient or pharmacophore but can be modified by the other constituents. Among the various properties of chemical compounds, pharmacological/biological activity plays a crucial role since it suggests uses of the compounds in the medical applications. However, chemical compounds may show some adverse and toxic effects which may prevent their use in medical practice. Activity is generally dosage-dependent. Further, it is common to have effects ranging from beneficial to adverse for one substance when going from low to high doses. Activity depends critically on fulfillment of the ADME criteria. To be an effective drug, a compound not only must be active against a target, but also possess the appropriate ADME (Absorption, Distribution, Metabolism, and ...
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