Saringosterol
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Saringosterol
Saringosterol is an isolate of ''Lessonia nigrescens'' that has activity against ''Mycobacterium tuberculosis ''Mycobacterium tuberculosis'' (M. tb) is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, ''M. tuberculosis'' has an unusual, waxy coating on its c ...''. References Sterols {{steroid-stub ...
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Lessonia Nigrescens
''Lessonia nigrescens'', the grey weed or giant grey weed, is a South American kelp species in the genus '' Lessonia''. There is at least two populations of the seaweed, marked by the difference in phenolic content. There is a subtidal population with higher phenol content and an intertidal population with a lighter phenol content. The difference in the phenolic content can be explained by the herbivory selection pressure due to the sea snail ''Tegula tridentata''. UV treatment induces the production of phlorotannins that accumulate in physodes. This weed contains the phytosterol saringosterol that shows an inhibitory effect on ''Mycobacterium tuberculosis ''Mycobacterium tuberculosis'' (M. tb) is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, ''M. tuberculosis'' has an unusual, waxy coating on its c ...'' growth.Inhibition of Mycobacterium tuberculosis growth by saringosterol ...
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Mycobacterium Tuberculosis
''Mycobacterium tuberculosis'' (M. tb) is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, ''M. tuberculosis'' has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining, and as a result, ''M. tuberculosis'' can appear weakly Gram-positive. Acid-fastness, Acid-fast stains such as Ziehl–Neelsen stain, Ziehl–Neelsen, or Fluorescence, fluorescent stains such as Auramine O, auramine are used instead to identify ''M. tuberculosis'' with a microscope. The physiology of ''M. tuberculosis'' is highly aerobic organism, aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the Mantoux test, tuberculin skin test, Acid-Fast Stain, acid-fast stain, Microbiological cultu ...
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